Kevin J Wiehe, PhD

Publications

Bonsignori, Mattia, Kevin Wiehe, Sebastian K. Grimm, Rebecca Lynch, Guang Yang, Daniel M. Kozink, Florence Perrin, et al. “An autoreactive antibody from an SLE/HIV-1 individual broadly neutralizes HIV-1.” J Clin Invest 124, no. 4 (April 2014): 1835–43. https://doi.org/10.1172/JCI73441.

PMID
24614107
Full Text

Song, Hongshuo, Bhavna Hora, Tanmoy Bhattacharya, Nilu Goonetilleke, Michael K. P. Liu, Kevin Wiehe, Hui Li, et al. “Reversion and T cell escape mutations compensate the fitness loss of a CD8+ T cell escape mutant in their cognate transmitted/founder virus.” Plos One 9, no. 7 (2014): e102734. https://doi.org/10.1371/journal.pone.0102734.

PMID
25028937
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Hwang, Kwan-Ki, Ashley M. Trama, Daniel M. Kozink, Xi Chen, Kevin Wiehe, Abby J. Cooper, Shi-Mao Xia, et al. “IGHV1-69 B cell chronic lymphocytic leukemia antibodies cross-react with HIV-1 and hepatitis C virus antigens as well as intestinal commensal bacteria.” Plos One 9, no. 3 (2014): e90725. https://doi.org/10.1371/journal.pone.0090725.

PMID
24614505
Full Text

Kepler, Thomas B., Supriya Munshaw, Kevin Wiehe, Ruijun Zhang, Jae-Sung Yu, Christopher W. Woods, Thomas N. Denny, et al. “Reconstructing a B-Cell Clonal Lineage. II. Mutation, Selection, and Affinity Maturation.” Front Immunol 5 (2014): 170. https://doi.org/10.3389/fimmu.2014.00170.

PMID
24795717
Full Text

Liao, Hua-Xin, Rebecca Lynch, Tongqing Zhou, Feng Gao, S Munir Alam, Scott D. Boyd, Andrew Z. Fire, et al. “Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus.” Nature 496, no. 7446 (April 25, 2013): 469–76. https://doi.org/10.1038/nature12053.

PMID
23552890
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Liao, Hua-Xin, Mattia Bonsignori, S Munir Alam, Jason S. McLellan, Georgia D. Tomaras, M Anthony Moody, Daniel M. Kozink, et al. “Vaccine induction of antibodies against a structurally heterogeneous site of immune pressure within HIV-1 envelope protein variable regions 1 and 2.” Immunity 38, no. 1 (January 24, 2013): 176–86. https://doi.org/10.1016/j.immuni.2012.11.011.

PMID
23313589
Full Text

Hwang, Howook, Thom Vreven, Troy W. Whitfield, Kevin Wiehe, and Zhiping Weng. “A machine learning approach for the prediction of protein surface loop flexibility.” Proteins 79, no. 8 (August 2011): 2467–74. https://doi.org/10.1002/prot.23070.

PMID
21633973
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Wiehe, K., T. B. Kepler, and S. C. Schmidler. “P19-50. Simulation of an MPER peptide samples epitope conformations of two broadly neutralizing antibodies.” Retrovirology 6, no. SUPPL. 3 (October 22, 2009). https://doi.org/10.1186/1742-4690-6-S3-P370.

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Wiehe, Kevin, Brian Pierce, Wei Wei Tong, Howook Hwang, Julian Mintseris, and Zhiping Weng. “The performance of ZDOCK and ZRANK in rounds 6-11 of CAPRI.” Proteins 69, no. 4 (December 1, 2007): 719–25. https://doi.org/10.1002/prot.21747.

PMID
17803212
Full Text

Pages