Kimberly Lynn Blackwell, MD

Adjunct Professor in the Department of Medicine
Member of the Duke Cancer Institute
Campus mail Duke Box 3893, Durham, NC 27710
Phone (919) 668-1748
Email address

Breast cancer angiogenesis
Breast cancer in younger women
Hormonal therapy
Neoadjurant therapy for breast cancer

Current Clinical Investigations

Principal Investigator, A Phase I-II Study of Neoadjuvant Evacet/Paclitaxel/Hyperthermia in Locally Advanced Breast Cancer Patients.

Investigator, Development of Screening Markers for Breast Cancer using Circulating Immune Complexes: Collaborative Study with Diagen Medical Technologies.

Principal Investigator, Use of Plasma D-Dimer as a Predictive Marker in Colorectal Carcinoma: Correlative Science Study with Genentech, Inc.

Principal Investigator, A randomized, Phase II study of gabapentin or glutamine to prevent the peripheral neuropathy/myalgia associated with weekly taxol administration in metastatic breast and lung cancer.

Investigator, A Phase 2, Randomized, Double-Masked, Multicenter Study of Two Dose Levels of ERA-923 for the treatment of Metastatic Breast Cancer in Postmenopausal Women who have failed Tamoxifen therapy. Genetics Institute.

Investigator, A Phase I Study of Combined Doxil/Hyperthermia in Stage IV Breast Cancer.

Education and Training

  • Fellow in Hematology-Oncology, Medicine, Duke University, 1997 - 2000
  • Medical Resident, Medicine, Duke University, 1994 - 1997
  • M.D., Mayo School of Health Sciences, 1994


Blackwell, KL. "Are all aromatase inhibitors alike?." Breast Cancer Res Treat 112 Suppl 1 (December 2008): 35-43.

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Anders, CK, Hsu, DS, Broadwater, G, Acharya, CR, Foekens, JA, Zhang, Y, Wang, Y, Marcom, PK, Marks, JR, Febbo, PG, Nevins, JR, Potti, A, and Blackwell, KL. "Young age at diagnosis correlates with worse prognosis and defines a subset of breast cancers with shared patterns of gene expression." Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology 26, no. 20 (July 2008): 3324-3330.

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Burstein, HJ, Storniolo, AM, Franco, S, Forster, J, Stein, S, Rubin, S, Salazar, VM, and Blackwell, KL. "A phase II study of lapatinib monotherapy in chemotherapy-refractory HER2-positive and HER2-negative advanced or metastatic breast cancer." Annals of Oncology : Official Journal of the European Society for Medical Oncology 19, no. 6 (June 2008): 1068-1074.

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Bullock, K, and Blackwell, K. "Clinical efficacy of taxane-trastuzumab combination regimens for HER-2-positive metastatic breast cancer." The Oncologist 13, no. 5 (May 2008): 515-525. (Review)

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Anders, C, Marcom, PK, Peterson, B, Gu, L, Unruhe, S, Welch, R, Lyons, P, Behera, M, Copland, S, Kimmick, G, Shaw, H, Snyder, S, Antenos, M, Woodruff, T, and Blackwell, K. "A pilot study of predictive markers of chemotherapy-related amenorrhea among premenopausal women with early stage breast cancer." Cancer Invest 26, no. 3 (April 2008): 286-295.

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Johnston, S, Trudeau, M, Kaufman, B, Boussen, H, Blackwell, K, LoRusso, P, Lombardi, DP, Ben Ahmed, S, Citrin, DL, DeSilvio, ML, Harris, J, Westlund, RE, Salazar, V, Zaks, TZ, and Spector, NL. "Phase II study of predictive biomarker profiles for response targeting human epidermal growth factor receptor 2 (HER-2) in advanced inflammatory breast cancer with lapatinib monotherapy." Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology 26, no. 7 (March 2008): 1066-1072.

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Demark-Wahnefried, W, Case, LD, Blackwell, K, Marcom, PK, Kraus, W, Aziz, N, Snyder, DC, Giguere, JK, and Shaw, E. "Results of a diet/exercise feasibility trial to prevent adverse body composition change in breast cancer patients on adjuvant chemotherapy." Clinical Breast Cancer 8, no. 1 (February 2008): 70-79.

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Herold, CI, and Blackwell, KL. "Aromatase inhibitors for breast cancer: proven efficacy across the spectrum of disease." Clinical Breast Cancer 8, no. 1 (February 2008): 50-64. (Review)

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Anders, CK, Acharya, CR, Hsu, DS, Broadwater, G, Garman, K, Foekens, JA, Zhang, Y, Wang, Y, Marcom, K, Marks, JR, Mukherjee, S, Nevins, JR, Blackwell, KL, and Potti, A. "Age-specific differences in oncogenic pathway deregulation seen in human breast tumors. (Published online)" PLoS One 3, no. 1 (January 2, 2008): e1373-.

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Blackwell, KL. "The significance of distant metastases in breast cancer." Breast (Edinburgh, Scotland) 17 Suppl 1 (January 1, 2008).