Lesley H. Curtis, PhD

Professor in Population Health Sciences
Professor in Medicine
Interim Executive Director, Duke Clinical Research Institute
Chair in the Department of Population Health Sciences
Member in the Duke Clinical Research Institute
Campus mail 2200 West Main Street, Suite 720-A, Erwin Square Building, Durham, NC 27705
Phone (919) 681-6709
Email address lesley.curtis@duke.edu

Dr. Curtis is a health services researcher who oversees a portfolio of projects that use observational data to address questions related to clinical and comparative effectiveness, pharmacoepidemiology, health care delivery, and epidemiological trends across a broad array of clinical conditions and clinical care settings. An expert in the use of Medicare claims data for health services and clinical outcomes research, she has led the linkage of Medicare claims with several large clinical registries and epidemiological cohort studies including the Framingham Heart Study and the Cardiovascular Health Study. 

Dr Curtis directs the Center for Pragmatic Health Systems Research at the Duke Clinical Research Institute and leads the Distributed Research Network Operations Center for PCORI’s National Clinical Research Network (PCORnet), working with health systems and patient networks to develop a harmonized data infrastructure for robust observational and interventional research.

Areas of expertise: Health Services Research and Health Policy

 

Education and Training

  • Ph.D., University of Rochester, 2000

Publications

Parikh, KS, Greiner, MA, Suzuki, T, DeVore, AD, Blackshear, C, Maher, JF, Curtis, LH, Hernandez, AF, O'Brien, EC, and Mentz, RJ. "Resting Heart Rate and Long-term Outcomes Among the African American Population Insights From the Jackson Heart Study." JAMA CARDIOLOGY 2, no. 2 (February 2017): 172-180.

Full Text

Cowie, MR, Blomster, JI, Curtis, LH, Duclaux, S, Ford, I, Fritz, F, Goldman, S, Janmohamed, S, Kreuzer, J, Leenay, M, Michel, A, Ong, S, Pell, JP, Southworth, MR, Stough, WG, Thoenes, M, Zannad, F, and Zalewski, A. "Electronic health records to facilitate clinical research." Clinical Research in Cardiology : Official Journal of the German Cardiac Society 106, no. 1 (January 2017): 1-9. (Review)

PMID
27557678
Full Text

Cooper, LB, Mi, X, Mentz, RJ, Green, JB, Anstrom, KJ, Hernandez, AF, and Curtis, LH. "Management of newly treated diabetes in Medicare beneficiaries with and without heart failure." Clinical Cardiology 40, no. 1 (January 2017): 38-45.

PMID
27783884
Full Text

Al-Khatib, SM, Yancy, CW, Solis, P, Becker, L, Benjamin, EJ, Carrillo, RG, Ezekowitz, JA, Fonarow, GC, Kantharia, BK, Kleinman, M, Nichol, G, and Varosy, PD. "2016 AHA/ACC Clinical Performance and Quality Measures for Prevention of Sudden Cardiac Death: A Report of the American College of Cardiology/American Heart Association Task Force on Performance Measures." Circulation. Cardiovascular Quality and Outcomes 10, no. 1 (January 2017): e000022-null. (Review)

PMID
27993943
Full Text

Cooper, LB, Hammill, BG, Peterson, ED, Pitt, B, Maciejewski, ML, Curtis, LH, and Hernandez, AF. "Characterization of Mineralocorticoid Receptor Antagonist Therapy Initiation in High-Risk Patients With Heart Failure." Circulation. Cardiovascular Quality and Outcomes 10, no. 1 (January 2017).

PMID
28073850
Full Text

Randolph, TC, Greiner, MA, Egwim, C, Hernandez, AF, Thomas, KL, Curtis, LH, Muntner, P, Wang, W, Mentz, RJ, and O'Brien, EC. "Associations Between Blood Pressure and Outcomes Among Blacks in the Jackson Heart Study." Journal of the American Heart Association 5, no. 12 (December 7, 2016).

PMID
27927632
Full Text

Mi, X, Hammill, BG, Curtis, LH, Lai, EC-C, and Setoguchi, S. "Use of the landmark method to address immortal person-time bias in comparative effectiveness research: a simulation study." Statistics in Medicine 35, no. 26 (November 2016): 4824-4836.

PMID
27350312
Full Text

Levine, GN, Bates, ER, Bittl, JA, Brindis, RG, Fihn, SD, Fleisher, LA, Granger, CB, Lange, RA, Mack, MJ, Mauri, L, Mehran, R, Mukherjee, D, Newby, LK, O'Gara, PT, Sabatine, MS, Smith, PK, Smith, SC, Halperin, JL, Al-Khatib, SM, Birtcher, KK, Bozkurt, B, Cigarroa, JE, Curtis, LH, Gentile, F, Gidding, S, Hlatky, MA, Ikonomidis, JS, Joglar, JA, Pressler, SJ, and Wijeysundera, DN. "2016 ACC/AHA guideline focused update on duration of dual antiplatelet therapy in patients with coronary artery disease: A report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines." The Journal of Thoracic and Cardiovascular Surgery 152, no. 5 (November 2016): 1243-1275.

PMID
27751237
Full Text

Maciejewski, ML, Mi, X, Curtis, LH, Ng, J, Haffer, SC, and Hammill, BG. "Few Disparities in Baseline Laboratory Testing After the Diuretic or Digoxin Initiation by Medicare Fee-For-Service Beneficiaries." Circulation. Cardiovascular Quality and Outcomes 9, no. 6 (November 2016): 714-722.

PMID
27756796
Full Text

Jones, WS, Roe, MT, Antman, EM, Pletcher, MJ, Harrington, RA, Rothman, RL, Oetgen, WJ, Rao, SV, Krucoff, MW, Curtis, LH, Hernandez, AF, and Masoudi, FA. "The Changing Landscape of Randomized Clinical Trials in Cardiovascular Disease." Journal of the American College of Cardiology 68, no. 17 (October 2016): 1898-1907. (Review)

PMID
27765193
Full Text

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