Lesley H. Curtis, PhD

Professor in Population Health Sciences
Professor in Medicine
Interim Executive Director, Duke Clinical Research Institute
Chair in the Department of Population Health Sciences
Member in the Duke Clinical Research Institute
Campus mail 215 Morris Street, Suite 210, Durham, NC 27701
Phone (919) 681-6709
Email address lesley.curtis@duke.edu

Dr. Curtis is a health services researcher who oversees a portfolio of projects that use observational data to address questions related to clinical and comparative effectiveness, pharmacoepidemiology, health care delivery, and epidemiological trends across a broad array of clinical conditions and clinical care settings. An expert in the use of Medicare claims data for health services and clinical outcomes research, she has led the linkage of Medicare claims with several large clinical registries and epidemiological cohort studies including the Framingham Heart Study and the Cardiovascular Health Study. 

Dr Curtis directs the Center for Pragmatic Health Systems Research at the Duke Clinical Research Institute and leads the Distributed Research Network Operations Center for PCORI’s National Clinical Research Network (PCORnet), working with health systems and patient networks to develop a harmonized data infrastructure for robust observational and interventional research.

Areas of expertise: Health Services Research and Health Policy

 

Education and Training

  • Ph.D., University of Rochester, 2000

Publications

Vemulapalli, Sreekanth, Luqin Deng, Manesh R. Patel, Meredith L. Kilgore, W Schuyler Jones, Lesley H. Curtis, Marguerite Ryan Irvin, et al. “National patterns in intensity and frequency of outpatient care for apparent treatment-resistant hypertension..” Am Heart J 186 (April 2017): 29–39. https://doi.org/10.1016/j.ahj.2017.01.008.

PMID
28454830
Full Text

Gerhard-Herman, Marie D., Heather L. Gornik, Coletta Barrett, Neal R. Barshes, Matthew A. Corriere, Douglas E. Drachman, Lee A. Fleisher, et al. “2016 AHA/ACC Guideline on the Management of Patients With Lower Extremity Peripheral Artery Disease: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines..” Circulation 135, no. 12 (March 21, 2017): e686–725. https://doi.org/10.1161/CIR.0000000000000470.

PMID
27840332
Full Text

Parikh, Kishan S., Melissa A. Greiner, Takeki Suzuki, Adam D. DeVore, Chad Blackshear, Joseph F. Maher, Lesley H. Curtis, Adrian F. Hernandez, Emily C. O’Brien, and Robert J. Mentz. “Resting Heart Rate and Long-term Outcomes Among the African American Population: Insights From the Jackson Heart Study..” Jama Cardiol 2, no. 2 (February 1, 2017): 172–80. https://doi.org/10.1001/jamacardio.2016.3234.

PMID
27681113
Full Text

Cowie, Martin R., Juuso I. Blomster, Lesley H. Curtis, Sylvie Duclaux, Ian Ford, Fleur Fritz, Samantha Goldman, et al. “Electronic health records to facilitate clinical research..” Clin Res Cardiol 106, no. 1 (January 2017): 1–9. https://doi.org/10.1007/s00392-016-1025-6.

PMID
27557678
Full Text

Cooper, Lauren B., Xiaojuan Mi, Robert J. Mentz, Jennifer B. Green, Kevin J. Anstrom, Adrian F. Hernandez, and Lesley H. Curtis. “Management of newly treated diabetes in Medicare beneficiaries with and without heart failure..” Clin Cardiol 40, no. 1 (January 2017): 38–45. https://doi.org/10.1002/clc.22603.

PMID
27783884
Full Text

Al-Khatib, Sana M., Clyde W. Yancy, Penelope Solis, Lance Becker, Emelia J. Benjamin, Roger G. Carrillo, Justin A. Ezekowitz, et al. “2016 AHA/ACC Clinical Performance and Quality Measures for Prevention of Sudden Cardiac Death: A Report of the American College of Cardiology/American Heart Association Task Force on Performance Measures..” Circ Cardiovasc Qual Outcomes 10, no. 1 (January 2017). https://doi.org/10.1161/HCQ.0000000000000022.

PMID
27993943
Full Text

Cooper, Lauren B., Bradley G. Hammill, Eric D. Peterson, Bertram Pitt, Matthew L. Maciejewski, Lesley H. Curtis, and Adrian F. Hernandez. “Characterization of Mineralocorticoid Receptor Antagonist Therapy Initiation in High-Risk Patients With Heart Failure..” Circ Cardiovasc Qual Outcomes 10, no. 1 (January 2017). https://doi.org/10.1161/CIRCOUTCOMES.116.002946.

PMID
28073850
Full Text

Marsolo, Keith, Laura G. Qualls, Bradley G. Hammill, Jeffrey S. Brown, and Lesley H. Curtis. “The PCORnet Learning Cycle..” In Amia. AMIA, 2017.

Scholars@Duke

Randolph, Tiffany C., Melissa A. Greiner, Chidiebube Egwim, Adrian F. Hernandez, Kevin L. Thomas, Lesley H. Curtis, Paul Muntner, Wei Wang, Robert J. Mentz, and Emily C. O’Brien. “Associations Between Blood Pressure and Outcomes Among Blacks in the Jackson Heart Study..” J Am Heart Assoc 5, no. 12 (December 7, 2016). https://doi.org/10.1161/JAHA.116.003928.

PMID
27927632
Full Text

Mi, Xiaojuan, Bradley G. Hammill, Lesley H. Curtis, Edward Chia-Cheng Lai, and Soko Setoguchi. “Use of the landmark method to address immortal person-time bias in comparative effectiveness research: a simulation study..” Stat Med 35, no. 26 (November 20, 2016): 4824–36. https://doi.org/10.1002/sim.7019.

PMID
27350312
Full Text

Pages