Lesley H. Curtis, PhD

Professor in Population Health Sciences
Professor in Medicine
Interim Executive Director, Duke Clinical Research Institute
Chair in the Department of Population Health Sciences
Member in the Duke Clinical Research Institute
Campus mail 215 Morris Street, Suite 210, Durham, NC 27701
Phone (919) 681-6709
Email address lesley.curtis@duke.edu

Dr. Curtis is a health services researcher who oversees a portfolio of projects that use observational data to address questions related to clinical and comparative effectiveness, pharmacoepidemiology, health care delivery, and epidemiological trends across a broad array of clinical conditions and clinical care settings. An expert in the use of Medicare claims data for health services and clinical outcomes research, she has led the linkage of Medicare claims with several large clinical registries and epidemiological cohort studies including the Framingham Heart Study and the Cardiovascular Health Study. 

Dr Curtis directs the Center for Pragmatic Health Systems Research at the Duke Clinical Research Institute and leads the Distributed Research Network Operations Center for PCORI’s National Clinical Research Network (PCORnet), working with health systems and patient networks to develop a harmonized data infrastructure for robust observational and interventional research.

Areas of expertise: Health Services Research and Health Policy

 

Education and Training

  • Ph.D., University of Rochester, 2000

Publications

Jones, W Schuyler, Xiaojuan Mi, Laura G. Qualls, Ryan S. Turley, Sreekanth Vemulapalli, Eric D. Peterson, Manesh R. Patel, and Lesley H. Curtis. “Significant variation in P2Y12 inhibitor use after peripheral vascular intervention in Medicare beneficiaries..” Am Heart J 179 (September 2016): 10–18. https://doi.org/10.1016/j.ahj.2016.06.002.

PMID
27595675
Full Text

WRITING COMMITTEE MEMBERS, Amer Heart, and Amer Heart ACC/AHA TASK FORCE MEMBERS. “2016 ACC/AHA/HFSA Focused Update on New Pharmacological Therapy for Heart Failure: An Update of the 2013 ACCF/AHA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Failure Society of America..” J Card Fail 22, no. 9 (September 2016): 659–69. https://doi.org/10.1016/j.cardfail.2016.07.001.

PMID
27394189
Full Text

Maciejewski, Matthew L., Xiaojuan Mi, Lesley H. Curtis, Judy Ng, Samuel C. Haffer, and Bradley G. Hammill. “Frequency of Disparities in Laboratory Testing After Statin Initiation in Subjects ≥65 Years..” Am J Cardiol 118, no. 3 (August 1, 2016): 376–82. https://doi.org/10.1016/j.amjcard.2016.05.019.

PMID
27289297
Full Text

Krishnamoorthy, Arun, Melissa A. Greiner, Alain G. Bertoni, Zubin J. Eapen, Emily C. O’Brien, Lesley H. Curtis, Adrian F. Hernandez, and Robert J. Mentz. “The Obesity and Heart Failure Epidemics Among African Americans: Insights From the Jackson Heart Study..” J Card Fail 22, no. 8 (August 2016): 589–97. https://doi.org/10.1016/j.cardfail.2016.03.004.

PMID
26975941
Full Text

Hyland, Kristen A., Melissa A. Greiner, Laura G. Qualls, Robert M. Califf, Adrian F. Hernandez, and Lesley H. Curtis. “TRENDS IN THE CARE AND OUTCOMES OF MEDICARE BENEFICIARIES WITH TYPE 2 DIABETES, 2002-2011..” Endocr Pract 22, no. 8 (August 2016): 920–34. https://doi.org/10.4158/EP15807.OR.

PMID
27042746
Full Text

DeVore, Adam D., Melissa A. Greiner, Puza P. Sharma, Laura G. Qualls, Phillip J. Schulte, Lauren B. Cooper, Robert J. Mentz, et al. “Development and validation of a risk model for in-hospital worsening heart failure from the Acute Decompensated Heart Failure National Registry (ADHERE)..” Am Heart J 178 (August 2016): 198–205. https://doi.org/10.1016/j.ahj.2016.04.021.

PMID
27502870
Full Text

Cooper, Lauren B., Bradley G. Hammill, Eric D. Peterson, Bertram Pitt, Matthew L. Maciejewski, Lesley H. Curtis, and Adrian F. Hernandez. “Laboratory Monitoring after Inpatient and Outpatient Initiation of Mineralocorticoid Receptor Antagonist Therapy in Patients with Heart Failure.” In Journal of Cardiac Failure, 22:S26–S26. Elsevier BV, 2016. https://doi.org/10.1016/j.cardfail.2016.06.087.

Full Text

Patel, Priyesh A., Li Liang, Prateeti Khazanie, Bradley G. Hammill, Gregg C. Fonarow, Clyde W. Yancy, Deepak L. Bhatt, Lesley H. Curtis, and Adrian F. Hernandez. “Antihyperglycemic Medication Use Among Medicare Beneficiaries With Heart Failure, Diabetes Mellitus, and Chronic Kidney Disease..” Circ Heart Fail 9, no. 7 (July 2016). https://doi.org/10.1161/CIRCHEARTFAILURE.115.002638.

PMID
27413035
Full Text

Heidenreich, Paul A., Penelope Solis, N. A. Mark Estes, Gregg C. Fonarow, Corrine Y. Jurgens, Joseph E. Marine, David D. McManus, and Robert L. McNamara. “2016 ACC/AHA Clinical Performance and Quality Measures for Adults With Atrial Fibrillation or Atrial Flutter: A Report of the American College of Cardiology/American Heart Association Task Force on Performance Measures..” Circ Cardiovasc Qual Outcomes 9, no. 4 (July 2016): 443–88. https://doi.org/10.1161/HCQ.0000000000000018.

PMID
27354018
Full Text

Khazanie, Prateeti, Melissa A. Greiner, Sana M. Al-Khatib, Jonathan P. Piccini, Mintu P. Turakhia, Paul D. Varosy, Frederick A. Masoudi, Lesley H. Curtis, Adrian F. Hernandez, and Adrian F. National Cardiovascular Data Registry. “Comparative Effectiveness of Cardiac Resynchronization Therapy Among Patients With Heart Failure and Atrial Fibrillation: Findings From the National Cardiovascular Data Registry's Implantable Cardioverter-Defibrillator Registry..” Circ Heart Fail 9, no. 6 (June 2016). https://doi.org/10.1161/CIRCHEARTFAILURE.115.002324.

PMID
27296396
Full Text

Pages