Lesley Huntley Curtis, PhD

Professor in Medicine
Member in the Duke Clinical Research Institute
Campus mail Box 3850 Med Ctr, Durham, NC 27710
Phone (919) 668-8673
Email address lesley.curtis@duke.edu

Lesley H. Curtis, PhD, is professor in medicine at the Duke University School of Medicine and directs the Center for Pragmatic Health Services Research in the Duke Clinical Research Institute.

A health services researcher by training, Dr. Curtis oversees a portfolio of projects that use observational data to address questions related to clinical and comparative effectiveness, pharmacoepidemiology, health care delivery, and epidemiological trends. Dr. Curtis has considerable experience analyzing Medicare claims data, large clinical registries, and prescription drug data, and has led the linkage of large clinical registries with longitudinal Medicare claims data.  In addition, Dr. Curtis has been responsible for the linkage of those data with longitudinal cohorts in the Cardiovascular Health Study, the Framingham Heart Study, the Jackson Heart Study, and the Multi-Ethnic Study of Atherosclerosis (MESA).

Experienced in facilitating large-scale multi-institutional research through the use of distributed health data networks, Curtis co-leads the Data Core for the FDA’s Mini-Sentinel Initiative, co-leads the Electronic Health Record Core for the NIH’s Health Care Systems Collaboratory, and co-leads the Data Standards, Security, Networking, and Infrastructure Task Force for the Patient-Centered Outcomes Research Initiative’s National Clinical Research Network.

Education and Training

  • Ph.D., University of Rochester, 2000

Publications

Steinberg, BA, Hammill, BG, Daubert, JP, Bahnson, TD, Douglas, PS, Qualls, LG, Pokorney, SD, Calkins, H, Curtis, LH, and Piccini, JP. "Periprocedural imaging and outcomes after catheter ablation of atrial fibrillation." Heart (British Cardiac Society) 100, no. 23 (December 2014): 1871-1877.

PMID
25082794
Full Text

Lad, EM, Hammill, BG, Qualls, LG, Wang, F, Cousins, SW, and Curtis, LH. "Anti-VEGF treatment patterns for neovascular age-related macular degeneration among medicare beneficiaries." American journal of ophthalmology 158, no. 3 (September 2014): 537-43.e2.

PMID
24857687
Full Text

Nishimura, RA, Otto, CM, Bonow, RO, Carabello, BA, Erwin, JP, Guyton, RA, O’Gara, PT, Ruiz, CE, Skubas, NJ, Sorajja, P, Sundt, TM, Thomas, JD, Anderson, JL, Halperin, JL, Albert, NM, Bozkurt, B, Brindis, RG, Creager, MA, Curtis, LH, DeMets, D, Guyton, RA, Hochman, JS, Kovacs, RJ, Ohman, EM, Pressler, SJ, Sellke, FW, Shen, W-K, Stevenson, WG, and Yancy, CW. "2014 AHA/ACC guideline for the management of patients with valvular heart disease." The Journal of Thoracic and Cardiovascular Surgery 148, no. 1 (July 2014): e1-e132.

Full Text

Pokorney, SD, Hammill, BG, Qualls, LG, Steinberg, BA, Curtis, LH, and Piccini, JP. "Cost analysis of periprocedural imaging in patients undergoing catheter ablation for atrial fibrillation." The American journal of cardiology 114, no. 2 (July 2014): 266-271.

PMID
24952929
Full Text

Al-Khatib, SM, Hellkamp, AS, Fonarow, GC, Mark, DB, Curtis, LH, Hernandez, AF, Anstrom, KJ, Peterson, ED, Sanders, GD, Al-Khalidi, HR, Hammill, BG, Heidenreich, PA, and Hammill, SC. "Association between prophylactic implantable cardioverter-defibrillators and survival in patients with left ventricular ejection fraction between 30% and 35%." JAMA 311, no. 21 (June 2014): 2209-2215.

PMID
24893088
Full Text

Anderson, JL, Heidenreich, PA, Barnett, PG, Creager, MA, Fonarow, GC, Gibbons, RJ, Halperin, JL, Hlatky, MA, Jacobs, AK, Mark, DB, Masoudi, FA, Peterson, ED, and Shaw, LJ. "ACC/AHA statement on cost/value methodology in clinical practice guidelines and performance measures: a report of the American College of Cardiology/American Heart Association Task Force on Performance Measures and Task Force on Practice Guidelines." Circulation 129, no. 22 (June 2014): 2329-2345.

PMID
24677315
Full Text

Nishimura, RA, Otto, CM, Bonow, RO, Carabello, BA, Erwin, JP, Guyton, RA, O'Gara, PT, Ruiz, CE, Skubas, NJ, Sorajja, P, Sundt, TM, and Thomas, JD. "2014 AHA/ACC Guideline for the Management of Patients With Valvular Heart Disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines." Circulation 129, no. 23 (June 2014): e521-e643.

PMID
24589853
Full Text

Nishimura, RA, Otto, CM, Bonow, RO, Carabello, BA, Erwin, JP, Guyton, RA, O'Gara, PT, Ruiz, CE, Skubas, NJ, Sorajja, P, Sundt, TM, and Thomas, JD. "2014 AHA/ACC Guideline for the Management of Patients With Valvular Heart Disease: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines." Circulation 129, no. 23 (June 2014): 2440-2492.

PMID
24589852
Full Text

Raebel, MA, Haynes, K, Woodworth, TS, Saylor, G, Cavagnaro, E, Coughlin, KO, Curtis, LH, Weiner, MG, Archdeacon, P, and Brown, JS. "Electronic clinical laboratory test results data tables: lessons from Mini-Sentinel." Pharmacoepidemiology and drug safety 23, no. 6 (June 2014): 609-618.

PMID
24677577
Full Text

Masoudi, FA, Mi, X, Curtis, LH, Peterson, PN, Curtis, JP, Fonarow, GC, Hammill, SC, Heidenreich, PA, Al-Khatib, SM, Piccini, JP, Qualls, LG, and Hernandez, AF. "Comparative effectiveness of cardiac resynchronization therapy with an implantable cardioverter-defibrillator versus defibrillator therapy alone: a cohort study." Annals of internal medicine 160, no. 9 (May 2014): 603-611.

PMID
24798523
Full Text

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