Manal F. Abdelmalek, MD

Professor of Medicine
Campus mail 03119 Hosp South, Suite 03107, Room 03125, Durham, NC 27710
Phone (919) 684-3262
Email address manal.abdelmalek@duke.edu

My research interests include metabolic liver disease, particularly obesity-related liver disease and its association with complications of the insulin resistance syndrome. I am interested in studying the clinical, environmental, and genetic risk factors for nonalcoholic fatty liver disease, new therapeutic options for treatment, and evaluating the impact of NAFLD from a public health perspective.

In Their Words

Education and Training

  • Fellow in Gastroenterology, Medicine, Mayo School of Health Sciences, 1995 - 1998
  • Medical Resident, Medicine, Mayo School of Health Sciences, 1992 - 1995
  • M.D., University Missouri Kansas City, 1992

Publications

Moylan, CA, Choi, SS, Dellinger, A, Pang, H, Abdelmalek, MF, Hampton, D, Chen, Y, Omenetti, A, Suzuki, A, Tillmann, HL, Acharya, CR, Potti, A, Hauser, MA, and Diehl, AM. "CONSERVED GENE EXPRESSION PATTERNS IN MYOFIBROBLASTIC MURINE AND HUMAN HEPATIC STELLATE CELLS AND NAFLD PATIENTS WITH LIVER FIBROSIS COMPATIBLE WITH EPITHELIAL-TO-MESENCHYMAL LIKE TRANSITION." October 2010.

Scholars@Duke

Moylan, CA, Abdelmalek, MF, Pang, H, Dellinger, A, Choi, SS, Omenetti, A, Chen, Y, Hampton, D, Syn, W-K, Suzuki, A, Tillmann, HL, Acharya, CR, Potti, A, Hauser, MA, and Diehl, AM. "SIGNALS FROM THE FIBROTIC LIVER IN PATIENTS WITH NAFLD MAY PROMOTE DIABETES AND OBESITY." October 2010.

Scholars@Duke

Piercy, DL, Suzuki, A, Feng, J, Pan, Y, Guy, CD, Diehl, AM, Chiang, AA, and Abdelmalek, MF. "OBSTRUCTIVE SLEEP APNEA WORSENS HEPATIC INFLAMMATION AND FIBROSIS IN PATIENTS WITH NONALCOHOLIC FATTY LIVER DISEASE." October 2010.

Scholars@Duke

Abdelmalek, MF, Suzuki, A, Guy, C, Unalp-Arida, A, Colvin, R, Johnson, RJ, Diehl, AM, and Nonalcoholic Steatohepatitis Clinical Research Network, . "Increased fructose consumption is associated with fibrosis severity in patients with nonalcoholic fatty liver disease." Hepatology (Baltimore, Md.) 51, no. 6 (June 2010): 1961-1971.

PMID
20301112
Full Text

Corbin, KD, Spencer, MD, da Costa, K-A, Sha, W, Abdelmalek, MF, Pan, Y, Suzuki, A, Guy, CD, Cardona, DM, Torquati, A, Diehl, AM, and Zeisel, SH. "Genotype-based hierarchical clustering reveals a panel of polymorphisms in one carbon metabolism that are associated with obesity." FASEB JOURNAL 24 (April 2010).

Scholars@Duke

Lavine, JE, Schwimmer, JB, Molleston, JP, Scheimann, AO, Murray, KF, Abrams, SH, Rosenthal, P, Sanyal, AJ, Robuck, PR, Brunt, EM, Unalp, A, Tonascia, J, and Nonalcoholic Steatohepatitis Clinical Research Network Research Group, . "Treatment of nonalcoholic fatty liver disease in children: TONIC trial design." Contemporary Clinical Trials 31, no. 1 (January 2010): 62-70.

PMID
19761871
Full Text

Abdelmalek, MF. "Is oil red-O staining and digital image analysis the gold standard for quantifying steatosis in the liver? Reply." Hepatology 51, no. 5 (2010): 1859-1860.

PMID
20432267
Full Text

Sánchez-Lozada, LG, Mu, W, Roncal, C, Sautin, YY, Abdelmalek, M, Reungjui, S, Le, M, Nakagawa, T, Lan, HY, Yu, X, and Johnson, RJ. "Comparison of free fructose and glucose to sucrose in the ability to cause fatty liver." European Journal of Nutrition 49, no. 1 (2010): 1-9.

PMID
19626358
Full Text

Abdelmalek, MF, Sanderson, SO, Angulo, P, Soldevila-Pico, C, Liu, C, Peter, J, Keach, J, Cave, M, Chen, T, McClain, CJ, and Lindor, KD. "Betaine for nonalcoholic fatty liver disease: results of a randomized placebo-controlled trial." Hepatology (Baltimore, Md.) 50, no. 6 (December 2009): 1818-1826.

PMID
19824078
Full Text

Suzuki, A, Guy, CD, Smith, AD, DeMaria, EJ, Pan, Y, Smith, MM, Diehl, AM, and Abdelmalek, MF. "GENDER AND HORMONAL STATUS ARE ASSOCIATED WITH SEVERITY OF HISTOLOGIC FEATURES AMONG PATIENTS WITH NON-ALCOHOLIC FATTY LIVER DISEASE." October 2009.

Scholars@Duke

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