Manal F. Abdelmalek, MD

Professor of Medicine
Campus mail 03119 Hosp South, Suite 03107, Room 03125, Durham, NC 27710
Phone (919) 684-3262
Email address manal.abdelmalek@duke.edu

My research interests include metabolic liver disease, particularly obesity-related liver disease and its association with complications of the insulin resistance syndrome. I am interested in studying the clinical, environmental, and genetic risk factors for nonalcoholic fatty liver disease, new therapeutic options for treatment, and evaluating the impact of NAFLD from a public health perspective.

In Their Words

Education and Training

  • Fellow in Gastroenterology, Medicine, Mayo School of Health Sciences, 1995 - 1998
  • Medical Resident, Medicine, Mayo School of Health Sciences, 1992 - 1995
  • M.D., University Missouri Kansas City, 1992

Publications

Garrett, ME, Abdelmalek, MF, Ashley-Koch, A, Hauser, MA, Moylan, CA, Pang, H, Diehl, AM, and Tillmann, HL. "IL28B rs12979860 is not associated with histologic features of NAFLD in a cohort of Caucasian North American patients." J Hepatol 58, no. 2 (February 2013): 402-403. (Letter)

PMID
23063570
Full Text

Youssef, NA, Abdelmalek, MF, Binks, M, Guy, CD, Omenetti, A, Smith, AD, Diehl, AME, and Suzuki, A. "Associations of depression, anxiety and antidepressants with histological severity of nonalcoholic fatty liver disease." Liver International 33, no. 7 (2013): 1062-1070.

Full Text

Garrett, ME, Abdelmalek, MF, Ashley-Koch, A, Hauser, MA, Moylan, CA, Pang, H, Diehl, AM, and Tillmann, HL. "IL28B rs12979860 is not associated with histologic features of NAFLD in a cohort of Caucasian North American patients." Journal of Hepatology 58, no. 2 (2013): 402-403.

Full Text

Swiderska-Syn, M, Suzuki, A, Guy, CD, Schwimmer, JB, Abdelmalek, MF, Lavine, JE, and Diehl, AM. "Hedgehog pathway and pediatric nonalcoholic fatty liver disease." Hepatology 57, no. 5 (2013): 1814-1825.

Full Text

Garrett, ME, Moylan, CA, Gibson, J, Yang, H, Pang, H, Dellinger, A, Suzuki, A, Tillmann, HL, Guy, CD, Abdelmalek, MF, Murphy, SK, Diehl, AM, Hauser, M, and Ashley-Koch, AE. "Expression QTL analysis of a gene expression signature which predicts advanced non-alcoholic fatty liver disease." October 2012.

Scholars@Duke

Suzuki, A, Pang, H, Guy, CD, Smith, AD, Diehl, AM, and Abdelmalek, MF. "Gender and Menopause Impact Severity of Fibrosis among Patients with Nonalcoholic Steatohepatitis." October 2012.

PMID
24123276
Scholars@Duke

Suzuki, A, Guy, CD, Pang, H, Smith, AD, Diehl, AM, and Abdelmalek, MF. "Impact of Gender and Menopause on Histologic Severity of Inflammation and Injury in patients with Nonalcoholic Fatty Liver Disease." October 2012.

Scholars@Duke

Syn, W-K, Agboola, KM, Swiderska, M, Michelotti, GA, Liaskou, E, Pang, H, Xie, G, Philips, G, Chan, IS, Karaca, GF, Pereira, TDA, Chen, Y, Mi, Z, Kuo, PC, Choi, SS, Guy, CD, Abdelmalek, MF, and Diehl, AM. "NKT-associated hedgehog and osteopontin drive fibrogenesis in non-alcoholic fatty liver disease." Gut 61, no. 9 (September 2012): 1323-1329.

PMID
22427237
Full Text

Abdelmalek, MF, Lazo, M, Horska, A, Bonekamp, S, Lipkin, EW, Balasubramanyam, A, Bantle, JP, Johnson, RJ, Diehl, AM, Clark, JM, and Fatty Liver Subgroup of Look AHEAD Research Group, . "Higher dietary fructose is associated with impaired hepatic adenosine triphosphate homeostasis in obese individuals with type 2 diabetes." Hepatology 56, no. 3 (September 2012): 952-960.

PMID
22467259
Full Text

Suzuki, A, Abdelmalek, MF, Schwimmer, JB, Lavine, JE, Scheimann, AO, Unalp-Arida, A, Yates, KP, Sanyal, AJ, Guy, CD, Diehl, AM, and Nonalcoholic Steatohepatitis Clinical Research Network, . "Association between puberty and features of nonalcoholic fatty liver disease." Clin Gastroenterol Hepatol 10, no. 7 (July 2012): 786-794.

PMID
22343513
Full Text

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