Manal F. Abdelmalek, MD

Professor of Medicine
Campus mail 03119 Hosp South, Suite 03107, Room 03125, Durham, NC 27710
Phone (919) 684-3262
Email address manal.abdelmalek@duke.edu

My research interests include metabolic liver disease, particularly obesity-related liver disease and its association with complications of the insulin resistance syndrome. I am interested in studying the clinical, environmental, and genetic risk factors for nonalcoholic fatty liver disease, new therapeutic options for treatment, and evaluating the impact of NAFLD from a public health perspective.

In Their Words

Education and Training

  • Fellow in Gastroenterology, Medicine, Mayo School of Health Sciences, 1995 - 1998
  • Medical Resident, Medicine, Mayo School of Health Sciences, 1992 - 1995
  • M.D., University Missouri Kansas City, 1992

Publications

Henao, R, Hasanaliyeva, N, Bell, LN, Wulff, J, Perichon, R, Moylan, CA, Lu, JT, Guy, CD, Diehl, AM, and Abdelmalek, MF. "Plasma Metabolomic Profiles Predict Advanced Hepatic Fibrosis in Patients with Nonalcoholic Fatty Liver Disease." October 2015.

Scholars@Duke

Moylan, CA, Murphy, SK, Grenier, C, Abdelmalek, MF, and Diehl, AM. "DNA Methylation Profiles of Fibrosis-Associated Gene in Blood Reflects Liver Fibrosis Severity in Human Nonalcoholic Fatty Liver Disease." October 2015.

Scholars@Duke

Hasanaliyeva, N, Patel, K, Guy, CD, Gruss, HJ, Streilein, R, Hall, R, Diehl, AM, and Abdelmalek, MF. "IL-8 and MCP1 are Independently Associated with Hepatic Fibrosis in Patients with Nonalcoholic Fatty Liver Disease." October 2015.

Scholars@Duke

Sanyal, AJ, Goodman, ZD, Abdelmalek, MF, Harrison, SA, Rockey, DC, Diehl, AM, Caldwell, SH, Shiffman, ML, Myers, RP, Schall, REA, Subramanian, M, McHutchison, JG, Ratziu, V, Afdhal, NH, and Bosch, J. "Clinical and histologic correlates of the hepatic venous pressure gradient (HVPG) in patients with compensated cirrhosis due to nonalcoholic steatohepatitis (NASH)." October 2015.

Scholars@Duke

Ratziu, V, Sanyal, AJ, Loomba, R, Caldwell, SH, Ghalib, RH, Torres, DM, McCullough, AJ, Muir, AJ, Myers, RP, Schall, REA, Subramanian, M, McHutchison, JG, Bosch, J, Harrison, SA, and Abdelmalek, MF. "Characterization of insulin resistance in patients with advanced fibrosis due to nonalcoholic steatohepatitis (NASH)." October 2015.

Scholars@Duke

Sanyal, AJ, Harrison, SA, Francque, SM, Bedossa, P, Serfaty, L, Romero-Gomez, M, Cales, P, Abdelmalek, MF, Caldwell, SH, Drenth, J, Anstee, QM, Hum, DW, Hanf, R, Roudot, A, Megnien, S, Staels, B, and Ratziu, V. "The hepatic and extra-hepatic profile of resolution of steatohepatitis induced by GFT-505." October 2015.

Scholars@Duke

Bosch, J, Ratziu, V, Rockey, DC, Ghalib, RH, Thuluvath, PJ, Schiefke, I, Flamm, SL, Abdelmalek, MF, Myers, RP, Schall, REA, Subramanian, M, McHutchison, JG, Goodman, ZD, Sanyal, AJ, and Afdhal, NH. "Correlation between noninvasive markers of fibrosis and the hepatic venous pressure gradient (HVPG) in patients with compensated cirrhosis due to nonalcoholic steatohepatitis (NASH)." October 2015.

Scholars@Duke

Abdelmalek, MF, and Day, C. "Sugar sweetened beverages and fatty liver disease: Rising concern and call to action." Journal of Hepatology 63, no. 2 (August 2015): 306-308.

PMID
26036988
Full Text

Deng, Y, Palmeri, ML, Rouze, NC, Rosenzweig, SJ, Abdelmalek, MF, and Nightingale, KR. "Analyzing the Impact of Increasing Mechanical Index and Energy Deposition on Shear Wave Speed Reconstruction in Human Liver." Ultrasound in medicine & biology 41, no. 7 (July 2015): 1948-1957.

PMID
25896024
Full Text

Guy, C, Suzuki, A, Abdelmalek, M, Burchette, J, and Diehl, AM. "Reply." Hepatology 61, no. 5 (May 2015): 1770-1771.

Full Text

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