Mark Andrew Herman, MD

Assistant Professor of Medicine
Assistant Research Professor in Pharmacology and Cancer Biology
Member of Duke Molecular Physiology Institute
Campus mail 300 N. Duke Street, Carmichael Building, Durham, NC 27701
Email address mark.herman@duke.edu

Education and Training

  • Endocrinology Fellowship, Beth Israel Deaconess Medical Center, 2003 - 2006
  • Internal Medicine Residency, University of Texas Southwestern Medical Center at Dallas Southwestern Medical School, 2000 - 2003
  • M.D., University of Texas Southwestern Medical Center at Dallas Southwestern Medical School, 2000

Publications

Jiang, ZG, Tapper, EB, Kim, M, Connelly, MA, Krawczyk, SA, Yee, EU, Herman, MA, Mukamal, KJ, and Lai, M. "Genetic Determinants of Circulating Lipoproteins in Nonalcoholic Fatty Liver Disease. (Accepted)" Journal of clinical gastroenterology 52, no. 5 (May 2018): 444-451.

PMID
28362682
Full Text

Herman, MA, Hannou, SA, McKeown, NM, and Haslam, DE. "Fructose metabolism and metabolic disease." The Journal of clinical investigation 128, no. 2 (February 1, 2018): 545-555. (Review)

Full Text

McKeown, NM, Dashti, HS, Ma, J, Haslam, DE, Kiefte-de Jong, JC, Smith, CE, Tanaka, T, Graff, M, Lemaitre, RN, Rybin, D, Sonestedt, E, Frazier-Wood, AC, Mook-Kanamori, DO, Li, Y, Wang, CA, Leermakers, ETM, Mikkilä, V, Young, KL, Mukamal, KJ, Cupples, LA, Schulz, C-A, Chen, T-A, Li-Gao, R, Huang, T, Oddy, WH, Raitakari, O, Rice, K, Meigs, JB, Ericson, U, Steffen, LM, Rosendaal, FR, Hofman, A, Kähönen, M, Psaty, BM, Brunkwall, L, Uitterlinden, AG, Viikari, J, Siscovick, DS, Seppälä, I, and North, KE et al. "Sugar-sweetened beverage intake associations with fasting glucose and insulin concentrations are not modified by selected genetic variants in a ChREBP-FGF21 pathway: a meta-analysis." Diabetologia 61, no. 2 (February 2018): 317-330.

PMID
29098321
Full Text

Kim, M, Astapova, II, Flier, SN, Hannou, SA, Doridot, L, Sargsyan, A, Kou, HH, Fowler, AJ, Liang, G, and Herman, MA. "Intestinal, but not hepatic, ChREBP is required for fructose tolerance." JCI insight 2, no. 24 (December 21, 2017).

PMID
29263303
Full Text

Ter Horst, KW, Gilijamse, PW, Demirkiran, A, van Wagensveld, BA, Ackermans, MT, Verheij, J, Romijn, JA, Nieuwdorp, M, Maratos-Flier, E, Herman, MA, and Serlie, MJ. "The FGF21 response to fructose predicts metabolic health and persists after bariatric surgery in obese humans." Molecular metabolism 6, no. 11 (November 2017): 1493-1502.

PMID
29107295
Full Text

Fisher, FM, Kim, M, Doridot, L, Cunniff, JC, Parker, TS, Levine, DM, Hellerstein, MK, Hudgins, LC, Maratos-Flier, E, and Herman, MA. "A critical role for ChREBP-mediated FGF21 secretion in hepatic fructose metabolism." Molecular metabolism 6, no. 1 (January 2017): 14-21.

PMID
28123933
Full Text

Haslam, DE, McKeown, NM, Herman, MA, Lichtenstein, AH, and Dashti, HS. "Interactions between Genetics and Sugar-Sweetened Beverage Consumption on Health Outcomes: A Review of Gene-Diet Interaction Studies." Frontiers in endocrinology 8 (January 2017): 368-. (Review)

PMID
29375475
Full Text

Kim, M-S, Krawczyk, SA, Doridot, L, Fowler, AJ, Wang, JX, Trauger, SA, Noh, H-L, Kang, HJ, Meissen, JK, Blatnik, M, Kim, JK, Lai, M, and Herman, MA. "ChREBP regulates fructose-induced glucose production independently of insulin signaling." The Journal of clinical investigation 126, no. 11 (November 2016): 4372-4386.

PMID
27669460
Full Text

Herman, MA, and Samuel, VT. "The Sweet Path to Metabolic Demise: Fructose and Lipid Synthesis." Trends in endocrinology and metabolism: TEM 27, no. 10 (October 2016): 719-730. (Review)

PMID
27387598
Full Text

Jiang, ZG, Tapper, EB, Connelly, MA, Pimentel, CFMG, Feldbrügge, L, Kim, M, Krawczyk, S, Afdhal, N, Robson, SC, Herman, MA, Otvos, JD, Mukamal, KJ, and Lai, M. "Steatohepatitis and liver fibrosis are predicted by the characteristics of very low density lipoprotein in nonalcoholic fatty liver disease." Liver international : official journal of the International Association for the Study of the Liver 36, no. 8 (August 2016): 1213-1220.

PMID
26815314
Full Text

Pages