Mark Franklin Newman, MD

Professor Emeritus of Anesthesiology
Merel H. Harmel Professor of Anesthesiology, in the School of Medicine
Member in the Duke Clinical Research Institute
Campus mail 200 Trent Drive, 1293 Orange Zone, Durham, NC 27710
Phone (919) 681-6581
Email address newma005@mc.duke.edu

Best known for his work in assessing and improving clinical outcomes and quality of life following cardiac surgery, Dr. Mark Newman is President of the Duke Private Diagnostic Clinic (The Duke Faculty Practice Organization) and the Merel H. Harmel Professor of Anesthesiology at Duke University Medical Center. In addition, Dr. Newman developed the Multicenter Perioperative Outcomes Research Group of the Duke Clinical Research Institute established at Duke in 2001 to further the study of strategies to improve the outcomes of patients undergoing surgery and anesthesia. Dr. Newman has received funding from the National Institute on Aging, the American Heart Association, the National Heart, Lung and Blood Institute, the Anesthesia Patient Safety Foundation, and the International Anesthesia Research Society  to investigate the impact of perioperative outcomes (neurocognitive decline, stroke, myocardial infarction, renal injury) on quantity and quality of life following cardiac surgery and resulting in numerous seminal publications in the New England Journal of Medicine, JAMA and Lancet. Dr. Newman is a popular lecturer and speaker, having appeared on NBC Nightly News and The Today Show and having spoken at more than 200 national and international meetings.  Dr. Newman recently stepped down as the Chairman of the Duke University Department after 13 years to assume the role of PDC President.  During Dr. Newman’s tenure the department grew exponentially doubling its clinical and academic funding, and developing many outstanding individuals that have gone on to leadership roles at Duke and other key academic institutions across the country.

Education and Training

  • M.D., University of Louisville, 1985

Publications

Stafford-Smith, M, Li, Y-J, Mathew, JP, Li, Y-W, Ji, Y, Phillips-Bute, BG, Milano, CA, Newman, MF, Kraus, WE, Kertai, MD, Shah, SH, Podgoreanu, MV, and Duke Perioperative Genetics and Safety Outcomes (PEGASUS) Investigative Team, . "Genome-wide association study of acute kidney injury after coronary bypass graft surgery identifies susceptibility loci." Kidney international 88, no. 4 (October 2015): 823-832.

PMID
26083657
Full Text

Klinger, RY, Thunberg, CA, White, WD, Fontes, M, Waldron, NH, Piccini, JP, Hughes, GC, Podgoreanu, MV, Stafford-Smith, M, Newman, MF, and Mathew, JP. "Intraoperative Magnesium Administration Does Not Reduce Postoperative Atrial Fibrillation After Cardiac Surgery." Anesthesia and analgesia 121, no. 4 (October 2015): 861-867.

PMID
26237622
Full Text

Kertai, MD, Li, Y-J, Ji, Y, Qi, W, Lombard, FW, Shah, SH, Kraus, WE, Stafford-Smith, M, Newman, MF, Milano, CA, Waldron, N, Podgoreanu, MV, Mathew, JP, and Duke Perioperative Genetics and Safety Outcomes (PEGASUS) Investigative Team, . "Genome-wide association study of new-onset atrial fibrillation after coronary artery bypass grafting surgery." American heart journal 170, no. 3 (September 2015): 580-90.e28.

PMID
26385043
Full Text

Bartels, K, Li, Y-J, Li, Y-W, White, WD, Laskowitz, DT, Kertai, MD, Stafford-Smith, M, Podgoreanu, MV, Newman, MF, and Mathew, JP. "Apolipoprotein epsilon 4 genotype is associated with less improvement in cognitive function five years after cardiac surgery: a retrospective cohort study." Canadian journal of anaesthesia = Journal canadien d'anesthesie 62, no. 6 (June 2015): 618-626.

PMID
25744138
Full Text

Kertai, MD, Li, Y-J, Li, Y-W, Ji, Y, Alexander, J, Newman, MF, Smith, PK, Joseph, D, Mathew, JP, Podgoreanu, MV, and Duke Perioperative Genetics and Safety Outcomes (PEGASUS) Investigative Team, . "Genome-wide association study of perioperative myocardial infarction after coronary artery bypass surgery." BMJ open 5, no. 5 (May 6, 2015): e006920-.

PMID
25948407
Full Text

Weisel, RD, Nussmeier, N, Newman, MF, Pearl, RG, Wechsler, AS, Ambrosio, G, Pitt, B, Clare, RM, Pieper, KS, Mongero, L, Reece, TL, Yau, TM, Fremes, S, Menasché, P, Lira, A, Harrington, RA, Ferguson, TB, and RED-CABG Executive and Steering Committees, . "Predictors of contemporary coronary artery bypass grafting outcomes." The Journal of thoracic and cardiovascular surgery 148, no. 6 (December 2014): 2720-6.e1-2-.

PMID
25218533
Full Text

Kertai, MD, Li, Y-W, Li, Y-J, Shah, SH, Kraus, WE, Fontes, ML, Stafford-Smith, M, Newman, MF, Podgoreanu, MV, Mathew, JP, and Duke Perioperative Genetics and Safety Outcomes (PEGASUS) Investigative Team, . "G protein-coupled receptor kinase 5 gene polymorphisms are associated with postoperative atrial fibrillation after coronary artery bypass grafting in patients receiving β-blockers." Circulation. Cardiovascular genetics 7, no. 5 (October 2014): 625-633.

PMID
25049040
Full Text

Welsby, IJ, Phillips-Bute, B, Mathew, JP, Newman, MF, Becker, R, Rao, S, Milano, CA, and Stafford-Smith, M. "ABO blood group influences transfusion and survival after cardiac surgery." Journal of thrombosis and thrombolysis 38, no. 3 (October 2014): 402-408.

PMID
24935230
Full Text

Fontes, MT, McDonagh, DL, Phillips-Bute, B, Welsby, IJ, Podgoreanu, MV, Fontes, ML, Stafford-Smith, M, Newman, MF, Mathew, JP, and Neurologic Outcome Research Group (NORG) of the Duke Heart Center, . "Arterial hyperoxia during cardiopulmonary bypass and postoperative cognitive dysfunction." J Cardiothorac Vasc Anesth 28, no. 3 (June 2014): 462-466.

PMID
23972739
Full Text

McDonagh, DL, Berger, M, Mathew, JP, Graffagnino, C, Milano, CA, and Newman, MF. "Neurological complications of cardiac surgery." The Lancet. Neurology 13, no. 5 (May 2014): 490-502. (Review)

PMID
24703207
Full Text

Pages