Mary E Klotman, MD

Professor of Medicine
R.J. Reynolds Professor of Medicine
Dean, School of Medicine
Professor in Molecular Genetics and Microbiology
Professor of Pathology
Member of the Duke Human Vaccine Institute
Campus mail DUMC 2927, Davison Building Room 125, Durham, NC 27710
Phone (919) 684-2455
Email address mary.klotman@duke.edu

Dr. Klotman became dean of the Duke School of Medicine in June 2017.

An accomplished clinician and scientist, Klotman’s research interests are focused on the molecular pathogenesis of Human Immunodeficiency Virus 1 (HIV-1) infection.

Among many important contributions to this field, Klotman and her team demonstrated that HIV resides in and evolves separately in kidney cells, a critical step in HIV-associated kidney disease. Her research group also has determined the role of soluble host factors involved in an innate immune response to HIV in an effort to improve prevention strategies, topical microbicides that could be used to block sexual transmission of HIV.

Most recently, her group has been defining the role of integrase-defective lentiviral vectors for the delivery of an HIV vaccine. (Read the announcement.)

In Their Words

Education and Training

  • Fellow in Infectious Diseases, Medicine, Duke University, 1983 - 1985
  • Resident, Medicine, Duke University, 1980 - 1983
  • M.D., Duke University, 1980

Publications

Kim, JH, Cooper, RA, Welty-Wolf, KE, Harrell, LJ, Zwadyk, P, and Klotman, ME. "Pseudomonas putrefaciens bacteremia." Reviews of Infectious Diseases 11, no. 1 (January 1989): 97-104.

PMID
2916100
Scholars@Duke

Buchbinder, A, Josephs, SF, Ablashi, D, Salahuddin, SZ, Klotman, ME, Manak, M, Krueger, GR, Wong-Staal, F, and Gallo, RC. "Polymerase chain reaction amplification and in situ hybridization for the detection of human B-lymphotropic virus." Journal of Virological Methods 21, no. 1-4 (September 1988): 191-197.

PMID
3182954
Full Text

Klotman, ME, Henry, SC, and Hamilton, JD. "Determinants of the source of cytomegalovirus in murine renal allograft recipients." Transplantation 44, no. 5 (November 1987): 636-639.

PMID
2825382
Scholars@Duke

Klotman, ME, and Hamilton, JD. "Cytomegalovirus pneumonia." Seminars in Respiratory Infections 2, no. 2 (June 1987): 95-103. (Review)

PMID
2827281
Scholars@Duke

Klotman, ME, Starnes, D, and Hamilton, JD. "The source of murine cytomegalovirus in mice receiving kidney allografts." The Journal of Infectious Diseases 152, no. 6 (December 1985): 1192-1196.

PMID
2999256
Full Text

Klotman, ME. "Laboratory detection of urinary tract infections." Kidney 18, no. 1 (January 1, 1985): 1-4.

Scholars@Duke

Pages