Matthew A. Sparks, MD

Associate Professor of Medicine
Campus mail 2 Genome Court, Msrb2 Room 1013, Box 103015, Durham, NC 27710
Phone (919) 684-9737
Email address matthew.sparks@duke.edu

I serve as the Program Director for the Nephrology Fellowship Program. My goal is to work with each fellow to ensure they develop a successful career in whatever direction they choose. I am the lead for the newly established Society for Early Education Scholars (SEEDS) in the Department of Medicine. The SEEDS Program is a year-long mentored education program designed for fellows planning careers as clinician educators or education scholars.

Nephrology Fellowship Program

My laboratory is interested in understanding how both the renin-angiotensin and prostanoid systems regulate blood pressure by altering blood flow to the kidney. We use a combination of physiologic and molecular techniques in genetically modified mice to probe questions about how changes in the micro circulation in the kidney alter sodium excretion. The overarching goal of this research is to identify novel mechanisms to target drug therapy for patients with hypertension. My research has been funded by the Department of Veterans Affairs Office of Research and Development and the American Heart Association. We also explore the link between pulmonary hypertension and CKD.

Sparks Laboratory Website

I'm also interested finding ways to promote medical education. My focus is on leveraging social media to enhance learning in nephrology. I serve as program director for the Nephrology Social Media Collective (NSMC) internship and member of the board of directors of nephrology journal club (NephJC), a non-profit organization dedicated to enhancing free online medical education in nephrology. I am also co-founder and advisory board member of the first nephrology blog associated with a journal- AJKD blog, the official blog of the American Journal of Kidney Diseases. Co-creator of the popular educational project NephMadness. Past deputy editor of Renal Fellow Network where I continue to remain as faculty lead. I am currently a member of the Nephrology Board of the American Board of Internal Medicine, the Scientific and Clinical Education Lifelong learning Committee Chair, Kidney in Cardiovascular Disease Council of the American Heart Association and am a fellow of the American Society of Nephrology, the American Heart Association, and the National Kidney Foundation. 

I serve as Education Director for KIDNEYcon- a yearly hands-on conference dedicated to advances in nephrology held in Little Rock, AR each April.

Listen to my podcast "The Nephron Segment"

@Nephro_Sparks on Twitter

Education and Training

  • Fellow in Nephrology, Medicine, Duke University School of Medicine, 2007 - 2011
  • Chief Resident, Medicine, University of Arkansas for Medical Sciences, College of Medicine, 2006 - 2007
  • Resident, Medicine, University of Arkansas for Medical Sciences, College of Medicine, 2003 - 2006
  • M.D., University of Arkansas for Medical Sciences, College of Medicine, 2003

Publications

Wolf, Erin, Edward J. Diaz, Alison N. Hollis, Thien A. Hoang, Hooman A. Azad, Katharine M. Bendt, Robert C. Griffiths, and Matthew A. Sparks. “Vascular type 1 angiotensin receptors control blood pressure by augmenting peripheral vascular resistance in female mice.” Am J Physiol Renal Physiol 315, no. 4 (October 1, 2018): F997–1005. https://doi.org/10.1152/ajprenal.00639.2017.

PMID
29897266
Full Text

Colbert, Gates B., Joel Topf, Kenar D. Jhaveri, Tom Oates, Michelle N. Rheault, Silvi Shah, Swapnil Hiremath, and Matthew A. Sparks. “The Social Media Revolution in Nephrology Education.” Kidney Int Rep 3, no. 3 (May 2018): 519–29. https://doi.org/10.1016/j.ekir.2018.02.003.

PMID
29854960
Full Text

Lerma, Edgar V., Matthew A. Sparks, and Joel Topf. Nephrology Secrets, 2018.

Scholars@Duke

Sparks, M. A., and Harpreet Singh. “Thrombotic Microangiopathies.” In Nephrology Secrets, edited by Matthew Sparks, Joel Topf, and Edgar Lerma, 2018.

Scholars@Duke

Sparks, M. A., and Harpreet Singh. “Thrombotic Microangiopathies.” In Nephrology Secrets, edited by Matthew Sparks, Joel Topf, and Edgar Lerma, 2018.

Scholars@Duke

Wang, Liming, Yonggang Sha, Jingyi Bai, William Eisner, Matthew A. Sparks, Anne F. Buckley, and Robert F. Spurney. “Podocyte-specific knockout of cyclooxygenase 2 exacerbates diabetic kidney disease.” Am J Physiol Renal Physiol 313, no. 2 (August 1, 2017): F430–39. https://doi.org/10.1152/ajprenal.00614.2016.

PMID
28490532
Full Text

Topf, Joel M., Matthew A. Sparks, Paul J. Phelan, Nikhil Shah, Edgar V. Lerma, Matthew P. M. Graham-Brown, Hector Madariaga, et al. “The Evolution of the Journal Club: From Osler to Twitter.” Am J Kidney Dis 69, no. 6 (June 2017): 827–36. https://doi.org/10.1053/j.ajkd.2016.12.012.

PMID
28233653
Full Text

Stegbauer, Johannes, Daian Chen, Marcela Herrera, Matthew A. Sparks, Ting Yang, Eva Königshausen, Susan B. Gurley, and Thomas M. Coffman. “Resistance to hypertension mediated by intercalated cells of the collecting duct.” Jci Insight 2, no. 7 (April 6, 2017): e92720. https://doi.org/10.1172/jci.insight.92720.

PMID
28405625
Full Text

Pages