Matthew Todd Roe, MD

Professor of Medicine
Member in the Duke Clinical Research Institute
Campus mail 2400 Pratt St, Durham, NC 27705
Phone (919) 668-8959
Email address roe00001@mc.duke.edu

My clinical activities focus upon general, preventive, and acute care cardiology.  I round regularly on the inpatient general cardiology and coronary care unit (CCU) services and i have a particular interest in the treatment and management of patients with acute myocardial infarction and cardiogenic shock.  In my outpatient clinic, I care for patients with a variety of cardiovascular conditions include chronic coronary artery disease, hypertension, hyperlipidemia, atrial fibrillation, congestive heart failure, aortic aneurysms, and peripheral arterial disease.  In this setting, I have a particular interest in cardiovascular risk factor modification and long-term treatment strategies to mitigate the risk of future cardiovascular events.

My research activities at the Duke Clinical Research Institute focus upon the coordination and leadership of randomized clinical trials evaluating new therapies for a variety of cardiovascular conditions (acute myocardial infarction, hyperlipidemia, coronary stent placement, peripheral arterial disease, and coronary artery disease) as well as observational registries that evaluate the same disease conditions.

Education and Training

  • Cardiology Fellow, Cardiology, Case Western Reserve University, 1996 - 1999
  • Medical Resident, Medicine, Duke University, 1993 - 1996
  • M.D., Duke University, 1993

Publications

Szarek, M, White, HD, Schwartz, GG, Alings, M, Bhatt, DL, Bittner, VA, Chiang, C-E, Diaz, R, Edelberg, JM, Goodman, SG, Hanotin, C, Harrington, RA, Jukema, JW, Kimura, T, Kiss, RG, Lecorps, G, Mahaffey, KW, Moryusef, A, Pordy, R, Roe, MT, Tricoci, P, Xavier, D, Zeiher, AM, Steg, PG, and ODYSSEY OUTCOMES Committees and Investigators, . "Alirocumab Reduces Total Nonfatal Cardiovascular and Fatal Events: The ODYSSEY OUTCOMES Trial." Journal of the American College of Cardiology 73, no. 4 (February 2019): 387-396.

PMID
30428396
Full Text

Mahajan, AM, Gandhi, H, Smilowitz, NR, Roe, MT, Hellkamp, AS, Chiswell, K, Gulati, M, and Reynolds, HR. "Seasonal and circadian patterns of myocardial infarction by coronary artery disease status and sex in the ACTION Registry-GWTG." International Journal of Cardiology 274 (January 2019): 16-20.

PMID
30217419
Full Text

Bulluck, H, Chan, MHH, Bryant, JA, Chai, P, Chawla, A, Chua, TS, Chung, Y-C, Fei, G, Ho, HH, Ho, AFW, Hoe, AJ, Imran, SS, Lee, C-H, Lim, SH, Liew, BW, Yun, PLZ, Hock, MOE, Paradies, V, Roe, MT, Teo, L, Wong, AS, Wong, E, Wong, PE, Watson, T, Chan, MY, Tan, JW, and Hausenloy, DJ. "Platelet inhibition to target reperfusion injury trial: Rationale and study design." Clinical Cardiology 42, no. 1 (January 2019): 5-12.

PMID
30421441
Full Text

Schwartz, GG, Steg, PG, Szarek, M, Bhatt, DL, Bittner, VA, Diaz, R, Edelberg, JM, Goodman, SG, Hanotin, C, Harrington, RA, Jukema, JW, Lecorps, G, Mahaffey, KW, Moryusef, A, Pordy, R, Quintero, K, Roe, MT, Sasiela, WJ, Tamby, J-F, Tricoci, P, White, HD, Zeiher, AM, and ODYSSEY OUTCOMES Committees and Investigators, . "Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome." The New England Journal of Medicine 379, no. 22 (November 7, 2018): 2097-2107.

PMID
30403574
Full Text

Ambrosy, AP, Cerbin, LP, Fudim, M, Clare, RM, Lokhnygina, Y, Braunwald, E, Califf, RM, Cannon, CP, Tershakovec, AM, Roe, MT, and Blazing, MA. "Natural History of Patients Postacute Coronary Syndrome Based on Heart Failure Status." The American Journal of Cardiology 122, no. 9 (November 2018): 1451-1458.

PMID
30180960
Full Text

Dodson, JA, Hochman, JS, Roe, MT, Chen, AY, Chaudhry, SI, Katz, S, Zhong, H, Radford, MJ, Udell, JA, Bagai, A, Fonarow, GC, Gulati, M, Enriquez, JR, Garratt, KN, and Alexander, KP. "The Association of Frailty With In-Hospital Bleeding Among Older Adults With Acute Myocardial Infarction: Insights From the ACTION Registry." Jacc. Cardiovascular Interventions 11, no. 22 (November 2018): 2287-2296.

PMID
30466828
Full Text

Hinohara, TT, Roe, MT, White, HD, Fox, KAA, Bhatt, DL, Hamm, C, Gurbel, PA, Aylward, PE, Wiviott, SD, Huber, K, Neely, ML, and Ohman, EM. "Outcomes of Patients Receiving Downstream Revascularization After Initial Medical Management for Non-ST-Segment Elevation Acute Coronary Syndromes (From the TRILOGY ACS Trial)." The American Journal of Cardiology 122, no. 8 (October 2018): 1322-1329.

PMID
30135019
Full Text

O'Brien, EC, Li, S, Thomas, L, Wang, TY, Roe, MT, and Peterson, ED. "The impact of clinical vs administrative claims coding on hospital risk-adjusted outcomes." Clinical Cardiology 41, no. 9 (September 22, 2018): 1225-1231.

PMID
30141213
Full Text

Yan, AT, Roe, MT, Neely, M, Cyr, DD, White, H, Fox, KAA, Prabhakaran, D, Armstrong, PW, Ohman, EM, and Goodman, SG. "Early discontinuation of prasugrel or clopidogrel in acute coronary syndromes: insights from the TRILOGY ACS trial." Coronary Artery Disease 29, no. 6 (September 2018): 469-476.

PMID
29652672
Full Text

Shavadia, JS, Roe, MT, Chen, AY, Lucas, J, Fanaroff, AC, Kochar, A, Fordyce, CB, Jollis, JG, Tamis-Holland, J, Henry, TD, Bagai, A, Kontos, MC, Granger, CB, and Wang, TY. "Association Between Cardiac Catheterization Laboratory Pre-Activation and Reperfusion Timing Metrics and Outcomes in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention: A Report From the ACTION Registry." Jacc. Cardiovascular Interventions 11, no. 18 (September 2018): 1837-1847.

PMID
30236357
Full Text

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