Megan Elizabeth Bowles Clowse, MD

Associate Professor of Medicine
Campus mail Baker House 07, Duke South, Trent Drive, Durham, NC 27710
Phone (919) 681-2045
Email address megan.clowse@duke.edu

Dr. Megan Clowse is an Associate Professor of Medicine in the Division of Rheumatology and Immunology.  Her clinical research focuses on the management of rheumatic diseases in pregnancy. She has cared for over 600 pregnancies in women with rheumatic disease, collecting information on these pregnancies initially in the Duke Autoimmunity in Pregnancy Registry and Repository, and now the MADRA (Maternal Autoimmune Disease Research Alliance) registry and repository.  She served on the Core Leadership Team for the inaugural American College of Rheumatology's Reproductive Health Guidelines, published January 2020.  Dr. Clowse created www.LupusPregnancy.org, a website dedicated to improving lupus pregnancy planning and management for patients and rheumatologists.  

Dr. Clowse was the founding director of the Duke Lupus Clinic, where she continues to see patients each week and mentor junior faculty researchers.  The team has developed a new approach to lupus classification and management and is currently collecting and analyzing patient- and physician-reported measures to  better clarify this construct.  

As the Co-Director of Duke Forge, Dr. Clowse has shepherding multiple Department of Medicine-funded studies to identify and build innovative approaches to using health data to improve patient care. 

In Their Words

Education and Training

  • Fellow in Rheumatology, Medicine, Johns Hopkins University, 2002 - 2005
  • Medical Residetn, Medicine, Johns Hopkins University, 1999 - 2002
  • M.D., Vanderbilt University, 1999
  • M.P.H., University of California - Los Angeles, 1994

Publications

Balevic, Stephen J., Christoph P. Hornik, Thomas P. Green, Megan E. B. Clowse, Daniel Gonzalez, Anil R. Maharaj, Laura E. Schanberg, et al. “Hydroxychloroquine in Patients with Rheumatic Disease Complicated by COVID-19: Clarifying Target Exposures and the Need for Clinical Trials.” J Rheumatol, May 11, 2020. https://doi.org/10.3899/jrheum.200493.

PMID
32393664
Full Text

Kang, SunAh, Jennifer L. Rogers, Megan E. B. Clowse, Saira Z. Sheikh, and Barbara J. Vilen. “Defects in lysosome acidification are evident in active, but not inactive, systemic lupus erythematosus (SLE).” In Journal of Immunology, Vol. 204, 2020.

Scholars@Duke

Sammaritano, Lisa R., Bonnie L. Bermas, Eliza E. Chakravarty, Christina Chambers, Megan E. B. Clowse, Michael D. Lockshin, Wendy Marder, et al. “2020 American College of Rheumatology Guideline for the Management of Reproductive Health in Rheumatic and Musculoskeletal Diseases.” Arthritis Care Res (Hoboken) 72, no. 4 (April 2020): 461–88. https://doi.org/10.1002/acr.24130.

PMID
32090466
Full Text

Sammaritano, Lisa R., Bonnie L. Bermas, Eliza E. Chakravarty, Christina Chambers, Megan E. B. Clowse, Michael D. Lockshin, Wendy Marder, et al. “2020 American College of Rheumatology Guideline for the Management of Reproductive Health in Rheumatic and Musculoskeletal Diseases.” Arthritis Rheumatol 72, no. 4 (April 2020): 529–56. https://doi.org/10.1002/art.41191.

PMID
32090480
Full Text

Birru Talabi, Mehret, Megan E. B. Clowse, Susan J. Blalock, Megan Hamm, and Sonya Borrero. “Perspectives of Adult Rheumatologists Regarding Family Planning Counseling and Care: A Qualitative Study.” Arthritis Care Res (Hoboken) 72, no. 3 (March 2020): 452–58. https://doi.org/10.1002/acr.23872.

PMID
30875455
Full Text

Eudy, A. M., D. Voora, R. A. Myers, and M. E. B. Clowse. “Effect of aspirin response signature gene expression on preterm birth and preeclampsia among women with lupus: a pilot study.” Lupus 28, no. 14 (December 2019): 1640–47. https://doi.org/10.1177/0961203319886069.

PMID
31684818
Full Text

Clowse, Megan E. B. “Pregnancy in Women With Lupus: We Have Come So Far and Have So Far to Go.” Ann Intern Med 171, no. 3 (August 6, 2019): 212–13. https://doi.org/10.7326/M19-1667.

PMID
31284297
Full Text

Birru Talabi, Mehret, Megan E. B. Clowse, Susan J. Blalock, Larry Moreland, Nalyn Siripong, and Sonya Borrero. “Contraception Use Among Reproductive-Age Women With Rheumatic Diseases.” Arthritis Care Res (Hoboken) 71, no. 8 (August 2019): 1132–40. https://doi.org/10.1002/acr.23724.

PMID
30106516
Full Text

Pisetsky, David S., Megan E. B. Clowse, Lisa G. Criscione-Schreiber, and Jennifer L. Rogers. “A Novel System to Categorize the Symptoms of Systemic Lupus Erythematosus.” Arthritis Care Res (Hoboken) 71, no. 6 (June 2019): 735–41. https://doi.org/10.1002/acr.23794.

PMID
30354033
Full Text

Pages