Megan Elizabeth Bowles Clowse, MD

Associate Professor of Medicine
Campus mail Baker House 07, Duke South, Trent Drive, Durham, NC 27710
Phone (919) 681-2045
Email address megan.clowse@duke.edu

I am a clinical researcher with a focus on the management of rheumatologic diseases in pregnancy.  Since 2007, I have collected prospective pregnancies in women with rheumatic disease in the Duke Autoimmunity in Pregnancy Registry, which currently includes over 300 pregnancies.  This registry includes clinical data, pregnancy outcomes, and a large sample repository.  In collaboration with Duke Pediatric Cardiology, we found that maternal use of hydroxychloroquine may be protective against congenital heart block from neonatal lupus.  I have also conducted studies on vasculitis and ovarian function and pregnancy and I am the director of the Vasculitis-Pregnancy Registry, through the Vasculitis Clinical Research Consortium, is an online pregnancy registry for women with these rare conditions.  I am starting a study to identify causes for the high rate of infertility among women with rheumatoid arthrits.  I am also working on several projects to better understand how psoriatic arthritis impacts pregnancy.  

In Their Words

Education and Training

  • Fellow in Rheumatology, Medicine, Johns Hopkins University, 2002 - 2005
  • Medical Residetn, Medicine, Johns Hopkins University, 1999 - 2002
  • M.D., Vanderbilt University, 1999
  • M.P.H., University of California at Los Angeles, 1994

Publications

Chakravarty, E, Clowse, MEB, Pushparajah, DS, Mertens, S, and Gordon, C. "Family planning and pregnancy issues for women with systemic inflammatory diseases: Patient and physician perspectives." BMJ Open 4, no. 2 (2014).

Full Text

Chakravarty, E, Clowse, MEB, Pushparajah, DS, Mertens, S, and Gordon, C. "Family planning and pregnancy issues for women with systemic inflammatory diseases: patient and physician perspectives." BMJ open 4, no. 2 (January 2014): e004081-.

PMID
24500612
Full Text

Schramm, AM, and Clowse, MEB. "Aspirin for prevention of preeclampsia in lupus pregnancy." Autoimmune Diseases 2014 (January 2014): 920467-. (Review)

PMID
24778868
Full Text

Peart, E, and Clowse, MEB. "Systemic lupus erythematosus and pregnancy outcomes: An update and review of the literature." Current Opinion in Rheumatology 26, no. 2 (2014): 118-123.

Full Text

Clowse, MEB, Grossman, JM, Merrill, JT, Askanase, A, Dvorkina, O, Lockshin, MD, and Aranow, C. "Predictors Of Damage Accrual Over a 2 Year Period In a Large Multi-Racial/Ethnic Lupus Cohort." October 2013.

Scholars@Duke

Kalunian, K, Clowse, MEB, Houssiau, F, Petri, MA, Kilgallen, B, Gordon, C, Strand, V, Bongardt, S, and Wallace, DJ. "Sustained British Isles Lupus Assessment Group-Measured Improvement In Moderately-and-Severely Affected Body Systems In Patients With Systemic Lupus Erythematosus By Epratuzumab: Results From An Open-Label Extension Study." October 2013.

Scholars@Duke

Chaudhary, P, and Clowse, MEB. "Prednisone Use Associated With Worse Outcomes In Rheumatoid Arthritis Pregnancies." October 2013.

Scholars@Duke

Clowse, MEB, Wolf, DC, Foerger, F, Cush, JJ, Stach, C, Kosutic, G, Williams, S, Maduka, C, and Mahadevan, U. "Retrospective Analysis Of Certolizumab Pegol Use During Pregnancy: Update Of Impact On Birth Outcomes." October 2013.

Scholars@Duke

Pedro, S, Chakravarty, E, Clowse, MEB, Schumacher, R, and Michaud, K. "The Impact Of Menopause In Rheumatoid Arthritis Activity." October 2013.

Scholars@Duke

Clowse, MEB, Houssiau, F, Petri, MA, Kilgallen, B, Kalunian, K, Strand, V, Bongardt, S, Gordon, C, and Wallace, DJ. "Epratuzumab Maintains Improvements In Disease Activity For Over 2 Years In Patients With Moderate-To-Severe Systemic Lupus Erythematosus: Results From An Open-Label Long-Term Extension Study." October 2013.

Scholars@Duke

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