Megan Elizabeth Bowles Clowse, MD

Associate Professor of Medicine
Campus mail Baker House 07, Duke South, Trent Drive, Durham, NC 27710
Phone (919) 681-2045
Email address megan.clowse@duke.edu

Dr. Megan Clowse is an Associate Professor of Medicine in the Division of Rheumatology and Immunology.  Her clinical research focuses on the management of rheumatic diseases in pregnancy. She has cared for over 600 pregnancies in women with rheumatic disease, collecting information on these pregnancies initially in the Duke Autoimmunity in Pregnancy Registry and Repository, and now the MADRA (Maternal Autoimmune Disease Research Alliance) registry and repository.  She served on the Core Leadership Team for the inaugural American College of Rheumatology's Reproductive Health Guidelines, published January 2020.  Dr. Clowse created www.LupusPregnancy.org, a website dedicated to improving lupus pregnancy planning and management for patients and rheumatologists.  

Dr. Clowse was the founding director of the Duke Lupus Clinic, where she continues to see patients each week and mentor junior faculty researchers.  The team has developed a new approach to lupus classification and management and is currently collecting and analyzing patient- and physician-reported measures to  better clarify this construct.  

As the Co-Director of Duke Forge, Dr. Clowse has shepherding multiple Department of Medicine-funded studies to identify and build innovative approaches to using health data to improve patient care. 

In Their Words

Education and Training

  • Fellow in Rheumatology, Medicine, Johns Hopkins University, 2002 - 2005
  • Medical Residetn, Medicine, Johns Hopkins University, 1999 - 2002
  • M.D., Vanderbilt University, 1999
  • M.P.H., University of California - Los Angeles, 1994

Publications

Eudy, Amanda M., Anna Maria Siega-Riz, Stephanie M. Engel, Nora Franceschini, Annie Green Howard, Megan E. B. Clowse, and Michelle Petri. “Response to: 'Postpartum breastfeeding status' by Betzold.” Ann Rheum Dis 78, no. 5 (May 2019): e38. https://doi.org/10.1136/annrheumdis-2018-213427.

PMID
29643109
Full Text

Eudy, Amanda M., Gary McDaniel, William W. Hurd, and Megan E. B. Clowse. “Fertility and Ovarian Reserve among Women with Rheumatoid Arthritis.” J Rheumatol 46, no. 5 (May 2019): 455–59. https://doi.org/10.3899/jrheum.180176.

PMID
30442826
Full Text

Balevic, Stephen J., Thomas P. Green, Megan E. B. Clowse, Amanda M. Eudy, Laura E. Schanberg, and Michael Cohen-Wolkowiez. “Pharmacokinetics of Hydroxychloroquine in Pregnancies with Rheumatic Diseases.” Clin Pharmacokinet 58, no. 4 (April 2019): 525–33. https://doi.org/10.1007/s40262-018-0712-z.

PMID
30255310
Full Text

Leverenz, David L., Amanda M. Eudy, Malithi Jayasundara, Tayseer Haroun, Gary McDaniel, W. Benjamin Nowell, Jeffrey R. Curtis, et al. “Contraception methods used by women with rheumatoid arthritis and psoriatic arthritis.” Clin Rheumatol 38, no. 4 (April 2019): 1207–12. https://doi.org/10.1007/s10067-018-04420-1.

PMID
30649682
Full Text

Birru Talabi, Mehret, Amanda M. Eudy, Malithi Jayasundara, Tayseer Haroun, W Benjamin Nowell, Jeffrey R. Curtis, Rachelle Crow-Hercher, C Whitney White, Seth Ginsberg, and Megan E. B. Clowse. “Pregnancy, Periods, and "The Pill": Exploring the Reproductive Experiences of Women with Inflammatory Arthritis.” Acr Open Rheumatol 1, no. 2 (April 2019): 125–32. https://doi.org/10.1002/acr2.1016.

PMID
31777789
Full Text

Harris, Nathaniel, Amanda Eudy, and Megan Clowse. “Patient-Reported Disease Activity and Adverse Pregnancy Outcomes in Systemic Lupus Erythematosus and Rheumatoid Arthritis.” In Arthritis Care Res (Hoboken), 71:390–97, 2019. https://doi.org/10.1002/acr.23621.

PMID
29908013
Full Text

Clowse, Megan E. B. “It Is Time to Modify Treatment to Enable More Women with Rheumatoid Arthritis to Have Successful Pregnancies.” J Rheumatol 46, no. 3 (March 2019): 223–25. https://doi.org/10.3899/jrheum.181036.

PMID
30824666
Full Text

Eudy, Amanda M., Anna Maria Siega-Riz, Stephanie M. Engel, Nora Franceschini, Annie Green Howard, Megan E. B. Clowse, and Michelle Petri. “Preconceptional Cardiovascular Health and Pregnancy Outcomes in Women with Systemic Lupus Erythematosus.” J Rheumatol 46, no. 1 (January 2019): 70–77. https://doi.org/10.3899/jrheum.171066.

PMID
30008449
Full Text

Balevic, Stephen J., Michael Cohen-Wolkowiez, Amanda M. Eudy, Thomas P. Green, Laura E. Schanberg, and Megan E. B. Clowse. “Hydroxychloroquine Levels throughout Pregnancies Complicated by Rheumatic Disease: Implications for Maternal and Neonatal Outcomes.” J Rheumatol 46, no. 1 (January 2019): 57–63. https://doi.org/10.3899/jrheum.180158.

PMID
30275257
Full Text

Clowse, M. E. B., A. M. Eudy, J. Revels, L. Neil, and G. D. Sanders. “Provider perceptions on the management of lupus during pregnancy: barriers to improved care.” Lupus 28, no. 1 (January 2019): 86–93. https://doi.org/10.1177/0961203318815594.

PMID
30522398
Full Text

Pages