Megan Elizabeth Bowles Clowse, MD

Associate Professor of Medicine
Campus mail Baker House 07, Duke South, Trent Drive, Durham, NC 27710
Phone (919) 681-2045
Email address megan.clowse@duke.edu

I am a clinical researcher with a focus on the management of rheumatologic diseases in pregnancy.  Since 2007, I have collected prospective pregnancies in women with rheumatic disease in the Duke Autoimmunity in Pregnancy Registry, which currently includes over 300 pregnancies.  This registry includes clinical data, pregnancy outcomes, and a large sample repository.  In collaboration with Duke Pediatric Cardiology, we found that maternal use of hydroxychloroquine may be protective against congenital heart block from neonatal lupus.  I have also conducted studies on vasculitis and ovarian function and pregnancy and I am the director of the Vasculitis-Pregnancy Registry, through the Vasculitis Clinical Research Consortium, is an online pregnancy registry for women with these rare conditions.  I am starting a study to identify causes for the high rate of infertility among women with rheumatoid arthrits.  I am also working on several projects to better understand how psoriatic arthritis impacts pregnancy.  

In Their Words

Education and Training

  • Fellow in Rheumatology, Medicine, Johns Hopkins University, 2002 - 2005
  • Medical Residetn, Medicine, Johns Hopkins University, 1999 - 2002
  • M.D., Vanderbilt University, 1999
  • M.P.H., University of California at Los Angeles, 1994

Publications

Clowse, MEB, Wallace, DJ, Weisman, M, James, A, Criscione-Schreiber, LG, and Pisetsky, DS. "Predictors of preterm birth in patients with mild systemic lupus erythematosus." Annals of the Rheumatic Diseases 72, no. 9 (2013): 1536-1539.

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Clowse, MEB, Richeson, RL, Pieper, C, and Merkel, PA. "Pregnancy outcomes among patients with vasculitis." Arthritis Care and Research 65, no. 8 (2013): 1370-1374.

PMID
23401494
Full Text

Tunks, RD, Clowse, MEB, Miller, SG, Brancazio, LR, and Barker, PCA. "Maternal autoantibody levels in congenital heart block and potential prophylaxis with antiinflammatory agents." Am J Obstet Gynecol 208, no. 1 (January 2013): 64.e1-64.e7.

PMID
23063019
Full Text

Harward, LE, Mitchell, K, Pieper, C, Copland, S, Criscione-Schreiber, LG, and Clowse, MEB. "The impact of cyclophosphamide on menstruation and pregnancy in women with rheumatologic disease." Lupus 22, no. 1 (January 2013): 81-86.

PMID
23263867
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Karol, DE, Criscione-Schreiber, LG, Lin, M, and Clowse, MEB. "Depressive symptoms and associated factors in systemic lupus erythematosus." Psychosomatics 54, no. 5 (2013): 443-450.

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Harward, LE, Mitchell, K, Pieper, C, Copland, S, Criscione-Schreiber, LG, and Clowse, MEB. "The impact of cyclophosphamide on menstruation and pregnancy in women with rheumatologic disease." LUPUS 22, no. 1 (2013): 81-86.

Full Text

Wahren-Herlenius, M, Sonesson, SE, and Clowse, MEG. "Neonatal Lupus Erythematosus." (October 2, 2012): 464-472. (Chapter)

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Clowse, MEB. "Pregnancy in Women with SLE." (October 2, 2012): 455-463. (Chapter)

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Aranow, C, Dall'Era, M, Massarotti, EM, Mackay, MC, Coca, A, Koumpouras, F, Levesque, MC, Chatham, WW, Clowse, MEB, Criscione-Schreiber, LG, Callahan, S, Goldmuntz, EA, Keyes-Elstein, L, Diamond, B, and Kamen, DL. "A Double-Blind Randomized Placebo-Controlled Trial of the Effect of Vitamin D3 On the Interferon Signature in Patients with Systemic Lupus Erythematosus." October 2012.

PMID
25777546
Scholars@Duke

Somers, TJ, Kurakula, PC, Criscione-Schreiber, L, Keefe, FJ, and Clowse, MEB. "Self-efficacy and pain catastrophizing in systemic lupus erythematosus: relationship to pain, stiffness, fatigue, and psychological distress." Arthritis Care Res (Hoboken) 64, no. 9 (September 2012): 1334-1340.

PMID
22505314
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