Megan Elizabeth Bowles Clowse, MD

Associate Professor of Medicine
Campus mail Baker House 07, Duke South, Trent Drive, Durham, NC 27710
Phone (919) 681-2045
Email address megan.clowse@duke.edu

I am a clinical researcher with a focus on the management of rheumatologic diseases in pregnancy.  Since 2007, I have collected prospective pregnancies in women with rheumatic disease in the Duke Autoimmunity in Pregnancy Registry, which currently includes over 300 pregnancies.  This registry includes clinical data, pregnancy outcomes, and a large sample repository.  In collaboration with Duke Pediatric Cardiology, we found that maternal use of hydroxychloroquine may be protective against congenital heart block from neonatal lupus.  I have also conducted studies on vasculitis and ovarian function and pregnancy and I am the director of the Vasculitis-Pregnancy Registry, through the Vasculitis Clinical Research Consortium, is an online pregnancy registry for women with these rare conditions.  I am starting a study to identify causes for the high rate of infertility among women with rheumatoid arthrits.  I am also working on several projects to better understand how psoriatic arthritis impacts pregnancy.  

In Their Words

Education and Training

  • Fellow in Rheumatology, Medicine, Johns Hopkins University, 2002 - 2005
  • Medical Residetn, Medicine, Johns Hopkins University, 1999 - 2002
  • M.D., Vanderbilt University, 1999
  • M.P.H., University of California at Los Angeles, 1994

Publications

Clowse, MEB, Wolf, DC, Foerger, F, Cush, JJ, Stach, C, Kosutic, G, Williams, S, Maduka, C, and Mahadevan, U. "Retrospective Analysis Of Certolizumab Pegol Use During Pregnancy: Update Of Impact On Birth Outcomes." October 2013.

Scholars@Duke

Pedro, S, Chakravarty, E, Clowse, MEB, Schumacher, R, and Michaud, K. "The Impact Of Menopause In Rheumatoid Arthritis Activity." October 2013.

Scholars@Duke

Clowse, MEB, Wallace, DJ, Weisman, M, James, A, Criscione-Schreiber, LG, and Pisetsky, DS. "Predictors of preterm birth in patients with mild systemic lupus erythematosus." Ann Rheum Dis 72, no. 9 (September 1, 2013): 1536-1539.

PMID
23361085
Full Text

Karol, DE, Criscione-Schreiber, LG, Lin, M, and Clowse, MEB. "Depressive symptoms and associated factors in systemic lupus erythematosus." Psychosomatics 54, no. 5 (September 2013): 443-450.

PMID
23274009
Full Text

Somers, TJ, Kurakula, PC, Criscione-Schreiber, L, Keefe, FJ, and Clowse, MEB. "Reply: To PMID 22505314." Arthritis Care Res (Hoboken) 65, no. 7 (July 2013): 1205-. (Letter)

PMID
23371927
Full Text

Tunks, RD, Clowse, MEB, Miller, SG, Brancazio, LR, and Barker, PCA. "Maternal autoantibody levels in congenital heart block and potential prophylaxis with antiinflammatory agents." Am J Obstet Gynecol 208, no. 1 (January 2013): 64.e1-64.e7.

PMID
23063019
Full Text

Harward, LE, Mitchell, K, Pieper, C, Copland, S, Criscione-Schreiber, LG, and Clowse, MEB. "The impact of cyclophosphamide on menstruation and pregnancy in women with rheumatologic disease." Lupus 22, no. 1 (January 2013): 81-86.

PMID
23263867
Full Text

Karol, DE, Criscione-Schreiber, LG, Lin, M, and Clowse, MEB. "Depressive symptoms and associated factors in systemic lupus erythematosus." Psychosomatics 54, no. 5 (2013): 443-450.

Full Text

Harward, LE, Mitchell, K, Pieper, C, Copland, S, Criscione-Schreiber, LG, and Clowse, MEB. "The impact of cyclophosphamide on menstruation and pregnancy in women with rheumatologic disease." LUPUS 22, no. 1 (2013): 81-86.

Full Text

Ostensen, M, and Clowse, M. "Pathogenesis of pregnancy complications in systemic lupus erythematosus." Current Opinion in Rheumatology 25, no. 5 (2013): 591-596.

PMID
23917157
Full Text

Pages