Megan Elizabeth Bowles Clowse, MD

Associate Professor of Medicine
Campus mail Baker House 07, Duke South, Trent Drive, Durham, NC 27710
Phone (919) 681-2045
Email address megan.clowse@duke.edu

Dr. Megan Clowse is an Associate Professor of Medicine, Rheumatology and Immunology.  Her clinical research focuses on the management of rheumatologic diseases in pregnancy. She has cared for over 600 pregnancies in women with rheumatic diseases, collecting information on these pregnancies initially in the Duke Autoimmunity in Pregnancy Registry and Repository, and now the Maternal Autoimmune Disease Research Alliance registry and repository.  She served on the Core Leadership Team for the inaugural American College of Rheumatology's Reproductive Health Guidelines, due in 2019.  Dr. Clowse has created www.LupusPregnancy.org, a website dedicated to improving lupus pregnancy planning and management for patients and rheumatologists.  

Dr. Clowse was the founding director of the Duke Lupus Clinic, where she continues to see patients each week and mentor junior faculty researchers.  The team has developed a new approach to lupus classification and management and is currently collecting and analyzing patient- and physician-reported measures to  better clarify this construct.  

As a Clinical Associate Director of Duke Forge, Dr. Clowse is shepherding several Department of Medicine funded pilot studies to identify and build innovative approaches to using health data to improve patient care. 

In Their Words

Education and Training

  • Fellow in Rheumatology, Medicine, Johns Hopkins University, 2002 - 2005
  • Medical Residetn, Medicine, Johns Hopkins University, 1999 - 2002
  • M.D., Vanderbilt University, 1999
  • M.P.H., University of California at Los Angeles, 1994

Publications

Eudy, AM, Siega-Riz, AM, Engel, SM, Franceschini, N, Howard, AG, Clowse, MEB, and Petri, M. "Gestational weight gain in women with systemic lupus erythematosus." Lupus 26, no. 6 (May 2017): 623-632.

PMID
27703053
Full Text

Machen, L, and Clowse, MEB. "Vasculitis and Pregnancy." Rheumatic diseases clinics of North America 43, no. 2 (May 2017): 239-247. (Review)

PMID
28390566
Full Text

Clowse, MEB, Wallace, DJ, Furie, RA, Petri, MA, Pike, MC, Leszczyński, P, Neuwelt, CM, Hobbs, K, Keiserman, M, Duca, L, Kalunian, KC, Galateanu, C, Bongardt, S, Stach, C, Beaudot, C, Kilgallen, B, Gordon, C, and EMBODY Investigator Group, . "Efficacy and Safety of Epratuzumab in Moderately to Severely Active Systemic Lupus Erythematosus: Results From Two Phase III Randomized, Double-Blind, Placebo-Controlled Trials." Arthritis & Rheumatology (Hoboken, N.J.) 69, no. 2 (February 2017): 362-375.

PMID
27598855
Full Text

Thorp, J, Clowse, MEB, Forger, F, Hwang, C, Dolhain, RJEM, van Tubergen, A, Shaughnessy, L, Simpson, J, Teil, M, Toublanc, N, Wang, M, and Hale, TW. "Evaluating transfer of certolizumab pegol into breast milk: results from a prospective, postmarketing, multicenter pharmacokinetic study." 37th Annual Pregnancy Meeting of the Society-for-Maternal-Fetal-Medicine (SMFM). Las Vegas, NV. January 23, 2017 - January 28, 2017.: MOSBY-ELSEVIER, January 1, 2017.

Scholars@Duke

Thorp, J, Clowse, MEB, Forger, F, Hwang, C, Dolhain, RJEM, van Tubergen, A, Shaughnessy, L, Simpson, J, Teil, M, Toublanc, N, Wang, M, and Hale, TW. "Evaluating transfer of certolizumab pegol into breast milk: results from a prospective, postmarketing, multicenter pharmacokinetic study." 37th Annual Pregnancy Meeting of the Society-for-Maternal-Fetal-Medicine (SMFM). Las Vegas, NV. January 23, 2017 - January 28, 2017.: MOSBY-ELSEVIER, January 1, 2017.

Scholars@Duke

Yazdany, J, Bansback, N, Clowse, M, Collier, D, Law, K, Liao, KP, Michaud, K, Morgan, EM, Oates, JC, Orozco, C, Reimold, A, Simard, JF, Myslinski, R, and Kazi, S. "Rheumatology Informatics System for Effectiveness: A National Informatics-Enabled Registry for Quality Improvement." Arthritis care & research 68, no. 12 (December 2016): 1866-1873.

PMID
27696755
Full Text

Mariette, X, Clowse, M, Förger, F, Hwang, C, Thorp, J, Dolhain, RJ, Van Tubergen, A, Shaughnessy, L, Simpson, J, Teil, M, Toublanc, N, Wang, M, and Hale, TW. "Évaluation du passage du certolizumab pegol dans le lait maternel: résultats d’une étude de pharmacocinétique post-AMM, prospective, multicentrique." Revue Du Rhumatisme 83 (November 2016): A100-A102.

Full Text

Simard, JF, Oates, J, Yazdany, J, Bansback, N, Collier, D, Law, K, Liao, K, Michaud, K, Morgan, E, Orozco, C, Reimold, A, Myslinski, R, Johansson, T, Kazi, S, and Clowse, MEB. "SLE and Uctd in the Rheumatology Informatics System for Effectiveness (RISE) Registry.": WILEY, October 1, 2016.

Scholars@Duke

Simard, JF, Oates, J, Yazdany, J, Bansback, N, Collier, D, Law, K, Liao, K, Michaud, K, Morgan, E, Orozco, C, Reimold, A, Myslinski, R, Johansson, T, Kazi, S, and Clowse, MEB. "SLE and Uctd in the Rheumatology Informatics System for Effectiveness (RISE) Registry.": WILEY, October 1, 2016.

Scholars@Duke

Yazdany, J, Bansback, N, Clowse, MEB, Collier, D, Laws, K, Liao, K, Michaud, K, Morgans, E, Oates, J, Orozco, C, Reimold, A, Simard, JF, Myslinski, R, Johansson, T, and Kazi, S. "Practice-Level Variation in Quality of Care in the Acr's Rheumatology Informatics System for Effectiveness (RISE) Registry.": WILEY, October 1, 2016.

Scholars@Duke

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