Megan Elizabeth Bowles Clowse, MD

Associate Professor of Medicine
Campus mail Baker House 07, Duke South, Trent Drive, Durham, NC 27710
Phone (919) 681-2045
Email address megan.clowse@duke.edu

I am a clinical researcher with a focus on the management of rheumatologic diseases in pregnancy.  Since 2007, I have collected prospective pregnancies in women with rheumatic disease in the Duke Autoimmunity in Pregnancy Registry, which currently includes over 300 pregnancies.  This registry includes clinical data, pregnancy outcomes, and a large sample repository.  In collaboration with Duke Pediatric Cardiology, we found that maternal use of hydroxychloroquine may be protective against congenital heart block from neonatal lupus.  I have also conducted studies on vasculitis and ovarian function and pregnancy and I am the director of the Vasculitis-Pregnancy Registry, through the Vasculitis Clinical Research Consortium, is an online pregnancy registry for women with these rare conditions.  I am starting a study to identify causes for the high rate of infertility among women with rheumatoid arthrits.  I am also working on several projects to better understand how psoriatic arthritis impacts pregnancy.  

In Their Words

Education and Training

  • Fellow in Rheumatology, Medicine, Johns Hopkins University, 2002 - 2005
  • Medical Residetn, Medicine, Johns Hopkins University, 1999 - 2002
  • M.D., Vanderbilt University, 1999
  • M.P.H., University of California at Los Angeles, 1994

Publications

Clowse, MEB, Behera, MA, Anders, CK, Copland, S, Coffman, CJ, Leppert, PC, and Bastian, LA. "Ovarian preservation by GnRH agonists during chemotherapy: a meta-analysis." J Womens Health (Larchmt) 18, no. 3 (March 2009): 311-319. (Review)

PMID
19281314
Full Text

Clowse, MEB, Behera, MA, Anders, CK, Copland, S, Coffman, CJ, Leppert, PC, and Bastian, LA. "GnRH: Authors' response." Journal of Women's Health 18, no. 9 (2009): 1473--.

Full Text

Robinson, AB, Ardoin, S, Clowse, MEB, and Criscione-Schreiber, LG. "Vitamin D Insufficiency is Common in Systemic Lupus Erythematosus and Associated with Greater Disease Activity." December 2008.

Scholars@Duke

Clowse, MEB, Jamison, M, Myers, E, and James, AH. "A national study of the complications of lupus in pregnancy." Am J Obstet Gynecol 199, no. 2 (August 2008): 127.e1-127.e6.

PMID
18456233
Full Text

Clowse, MEB. "Impact of pregnancy on rheumatoid arthritis activity." Future Rheumatology 3, no. 6 (2008): 527-531.

Full Text

Clowse, MEB. "Lupus activity in pregnancy." Rheum Dis Clin North Am 33, no. 2 (May 2007): 237-v. (Review)

PMID
17499705
Full Text

Clowse, MEB, and Petri, M. "Pregnancy." Systemic Lupus Erythematosus: A Companion to Rheumatology (2007): 449-459.

Full Text

Clowse, MEB, Magder, L, Witter, F, and Petri, M. "Hydroxychloroquine in lupus pregnancy." Arthritis Rheum 54, no. 11 (November 2006): 3640-3647.

PMID
17075810
Full Text

Clowse, MEB, Magder, LS, Witter, F, and Petri, M. "Risk factors for pregnancy loss in women with lupus." October 2006.

Full Text

Clowse, MEB, Jamison, MG, Myers, E, and James, AH. "National study of medical complications in SLE pregnancies." September 2006.

Scholars@Duke

Pages