Michael August Blazing, MD

Associate Professor of Medicine
Campus mail 7412HOSP North, Durham, NC 27710
Phone (919) 681-3945
Email address blazi001@mc.duke.edu

General focus: My research interests are in primary and secondary prevention of cardiovascular disease. Specifically, I am looking at compliance issues within the cardiology division and in the University as a whole with regard to evidence based treatment and secondary prevention of cardiovascular disease. I am using both retrospective and prospective collection of discharge data to try and analyze these trends. In the future, we hope to begin clinical trials with regard to various issues which are outstanding in primary and secondary prevention. Some of the issues include treatment of hypercholesterolemia in elderly patients, differences between the various statins with regard to affects on lipid profiles, and early treatment of hypercholesterolemia after MI.

As part of my work, I have served as a consultant with various drug companies with regard to focusing on active issues and treatment of hypercholesterolemia.

Key words: Primary prevention, secondary prevention, hyperlipidemia, homocysteine, and hypertension.

In Their Words

Education and Training

  • M.D., University of California, San Francisco, School of Medicine, 1987

Publications

Murphy, Sabina A., Christopher P. Cannon, Stephen D. Wiviott, James A. de Lemos, Michael A. Blazing, Carolyn H. McCabe, Robert M. Califf, and Eugene Braunwald. “Effect of intensive lipid-lowering therapy on mortality after acute coronary syndrome (a patient-level analysis of the Aggrastat to Zocor and Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis in Myocardial Infarction 22 trials)..” Am J Cardiol 100, no. 7 (October 1, 2007): 1047–51. https://doi.org/10.1016/j.amjcard.2007.04.053.

PMID
17884359
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Martin, Mike G., Amer K. Ardati, Shannon M. Dunlay, Amy P. Abernethy, and Michael A. Blazing. “Small cell lung cancer presenting as a paraneoplastic syndrome characterized by recurrent episodic hypotension and bradycardia: case report..” Chest 131, no. 1 (January 2007): 290–93. https://doi.org/10.1378/chest.06-1281.

PMID
17218589
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Evans, Elizabeth S., Robert G. Prosnitz, Xiaoli Yu, Su-Min Zhou, Donna R. Hollis, Terence Z. Wong, Kim L. Light, Patricia H. Hardenbergh, Michael A. Blazing, and Lawrence B. Marks. “Impact of patient-specific factors, irradiated left ventricular volume, and treatment set-up errors on the development of myocardial perfusion defects after radiation therapy for left-sided breast cancer..” Int J Radiat Oncol Biol Phys 66, no. 4 (November 15, 2006): 1125–34. https://doi.org/10.1016/j.ijrobp.2006.06.025.

PMID
17145533
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Lemos, James A. de, Stephen D. Wiviott, Sabina A. Murphy, Michael A. Blazing, Eldrin F. Lewis, Robert M. Califf, Marc A. Pfeffer, and Eugene Braunwald. “Evaluation of the National Cholesterol Education Program Adult Treatment Panel III algorithm for selecting candidates for statin therapy: insights from the A to Z trial..” Am J Cardiol 98, no. 6 (September 15, 2006): 739–42. https://doi.org/10.1016/j.amjcard.2006.03.060.

PMID
16950174
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Morrow, David A., James A. de Lemos, Marc S. Sabatine, Stephen D. Wiviott, Michael A. Blazing, Amy Shui, Nader Rifai, Robert M. Califf, and Eugene Braunwald. “Clinical relevance of C-reactive protein during follow-up of patients with acute coronary syndromes in the Aggrastat-to-Zocor Trial..” Circulation 114, no. 4 (July 25, 2006): 281–88. https://doi.org/10.1161/CIRCULATIONAHA.106.628909.

PMID
16847150
Full Text

Briel, Matthias, Gregory G. Schwartz, Peter L. Thompson, James A. de Lemos, Michael A. Blazing, Gerrit-Anne van Es, Meral Kayikçioglu, et al. “Effects of early treatment with statins on short-term clinical outcomes in acute coronary syndromes: a meta-analysis of randomized controlled trials..” Jama 295, no. 17 (May 3, 2006): 2046–56. https://doi.org/10.1001/jama.295.17.2046.

PMID
16670413
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Wiviott, Stephen D., James A. de Lemos, Christopher P. Cannon, Michael Blazing, Sabina A. Murphy, Carolyn H. McCabe, Robert Califf, and Eugene Braunwald. “A tale of two trials: a comparison of the post-acute coronary syndrome lipid-lowering trials A to Z and PROVE IT-TIMI 22..” Circulation 113, no. 11 (March 21, 2006): 1406–14. https://doi.org/10.1161/CIRCULATIONAHA.105.586347.

PMID
16534008
Full Text

Zeng, J., J. Zhang, L. Koweek, M. Blazing, S. Zhou, and L. Marks. “SU‐FF‐T‐119: Cardiac Dose Heterogeneity and Relationship to Tumor Location in Patients Receiving Radiation for Lung Cancer.” In Medical Physics, Vol. 33, 2006. https://doi.org/10.1118/1.2241044.

Full Text

Evans, E., X. Yu, R. Prosnitz, S. Zhou, T. Wong, K. Light, P. Hardenbergh, M. Blazing, and L. Marks. “SU‐FF‐J‐131: Is There a Relationship Between Body Mass Index, Treatment Set‐Up Errors, and the Development of Myocardial Perfusion Defects Following Radiation Therapy for Left‐Sided Breast Cancer?.” In Medical Physics, Vol. 33, 2006. https://doi.org/10.1118/1.2240907.

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Morrow, David A., James A. de Lemos, Michael A. Blazing, Marc S. Sabatine, Sabina A. Murphy, Petr Jarolim, Harvey D. White, et al. “Prognostic value of serial B-type natriuretic peptide testing during follow-up of patients with unstable coronary artery disease..” Jama 294, no. 22 (December 14, 2005): 2866–71. https://doi.org/10.1001/jama.294.22.2866.

PMID
16352794
Full Text

Pages