Nathan Nicely, Ph.D., is an Assistant Professor of Medicine with the Duke Human Vaccine Institute and Director of the Duke University X-ray Crystallography shared resource. His major research interests lie in the structural biology of anti-HIV antibodies and HIV virion coat proteins. Dr. Nicely received his Ph.D. in Structural and Molecular Biochemistry from NC State University in 2005 with Dr. Carla Mattos. He then completed a postdoctoral fellowship with Dr. Al Claiborne in the Center for Structural Biology at Wake Forest University. After a brief stint working in computational biology and bioinformatics with the Renaissance Computing Institute at the University of North Carolina, Dr. Nicely came to the Duke Human Vaccine Institute in early 2008 to complete the construction of the X-ray crystallography facility and to undertake the DHVI's structural biology program.
The X-ray Crystallography Shared Resource aims to provide the full range of services necessary to determine macromolecular structures. The facility was constructed in mid-2008 and officially opened its doors to the structural biology community in late 2009. The overall goal of the crystallography lab is to centralize all the necessary instrumentation as well as experienced expertise requisite to produce validated, high impact crystal structures for the Duke Human Vaccine Institute’s structural aims as well as any other investigator on campus with similar goals. The core lab offers everything from protein production to structure determination and publishing. The Shared Resource supports entry points for labs that are interested in expanding their research projects to include structural biology aims from basic methodological advice to full collaboration. A full description of the lab and its publications can be found at its website. Dr. Nicely enjoys engaging in the day-to-day operations of the crystallography facility, including user training and assistance as well as maintenance of the hardware and software that support the science.
Education and Training
- Ph.D., North Carolina State University, 2005
- B.S., North Carolina State University, 2000