Nathan Maclyn Thielman, MD

Professor of Medicine
Research Professor of Global Health
Professor of Pathology
Campus mail 310 Trent Drive, Room 201, Trent Hall, Durham, NC 27710
Phone (919) 668-7174

Broadly, my research focuses on a range of clinical and social issues that affect persons living with or at risk for HIV infection in resource-poor settings. In Tanzania, our group is applying novel methods to optimize HIV testing uptake among high-risk groups. We recently demonstrated that the Discrete Choice Experiment (DCE), a form of stated preference survey research, is a robust tool for identifying (a) which characteristics of HIV testing options are most preferred by different populations and (b) which tradeoffs individuals make in evaluating testing options. Building on more than a decade of productive HIV testing research in the Kilimanjaro Region, the next phase of our NIMH funded project will test the hypothesis that DCE-derived HIV testing options significantly increases rates of testing among groups at high risk for HIV infection. This work holds promise not only for optimizing HIV testing uptake in the Kilimanjaro Region, but also for applying novel tools in the service of translational epidemiology and implementation research.

Education and Training

  • Fellow in Infectious Diseases, Medicine, University of Virginia, 1993 - 1996
  • Medical Resident, Medicine, Duke University, 1990 - 1993
  • M.D., Duke University, 1990
  • M.P.H., University of North Carolina - Chapel Hill, 1989


Miller, W. C., N. M. Thielman, N. Swai, J. P. Cegielski, J. Shao, D. Manyenga, J. Mlalasi, and G. J. Lallinger. “Diagnosis and screening of HIV/AIDS using clinical criteria in Tanzanian adults.” J Acquir Immune Defic Syndr Hum Retrovirol 9, no. 4 (August 1, 1995): 408–14.


Fonteles, M., G. Fang, N. M. Thielman, P. S. Yotseff, and R. L. Guerrant. “Role of platelet activating factor in the inflammatory and secretory effects of Clostridium difficile toxin A.” J Lipid Mediat Cell Signal 11, no. 2 (March 1995): 133–43.

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Guerrant, R. L., G. D. Fang, N. M. Thielman, and M. C. Fonteles. “Role of platelet activating factor in the intestinal epithelial secretory and Chinese hamster ovary cell cytoskeletal responses to cholera toxin.” Proc Natl Acad Sci U S A 91, no. 20 (September 27, 1994): 9655–58.

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