Nathan Maclyn Thielman, MD

Professor of Medicine
Research Professor of Global Health
Professor of Pathology
Campus mail 310 Trent Drive, Room 201, Trent Hall, Durham, NC 27710
Phone (919) 668-7174

Broadly, my research focuses on a range of clinical and social issues that affect persons living with or at risk for HIV infection in resource-poor settings. In Tanzania, our group is applying novel methods to optimize HIV testing uptake among high-risk groups. We recently demonstrated that the Discrete Choice Experiment (DCE), a form of stated preference survey research, is a robust tool for identifying (a) which characteristics of HIV testing options are most preferred by different populations and (b) which tradeoffs individuals make in evaluating testing options. Building on more than a decade of productive HIV testing research in the Kilimanjaro Region, the next phase of our NIMH funded project will test the hypothesis that DCE-derived HIV testing options significantly increases rates of testing among groups at high risk for HIV infection. This work holds promise not only for optimizing HIV testing uptake in the Kilimanjaro Region, but also for applying novel tools in the service of translational epidemiology and implementation research.

Education and Training

  • Fellow in Infectious Diseases, Medicine, University of Virginia, 1993 - 1996
  • Medical Resident, Medicine, Duke University, 1990 - 1993
  • M.D., Duke University, 1990
  • M.P.H., University of North Carolina - Chapel Hill, 1989

Publications

Halfon, Johanna, Nathan Thielman, Washington Hill, and Stephen Rulisa. “Alarming Rates of Antibiotic Resistance Among Organisms Causing Post-Cesarean Section Peritonitis in Rwanda [19J].” In Obstetrics & Gynecology, 127:86S-86S. Ovid Technologies (Wolters Kluwer Health), 2016. https://doi.org/10.1097/01.aog.0000483788.70251.3e.

Full Text

Stanifer, John W., Joseph R. Egger, Elizabeth L. Turner, Nathan Thielman, Uptal D. Patel, and Uptal D. Comprehensive Kidney Disease Assessment for Risk factors, epidemiology, Knowledge, and Attitudes (CKD AFRiKA) Study. “Neighborhood clustering of non-communicable diseases: results from a community-based study in Northern Tanzania.” Bmc Public Health 16 (March 5, 2016): 226. https://doi.org/10.1186/s12889-016-2912-5.

PMID
26944390
Full Text

Barroso, Julie, Angela M. Bengtson, Bradley N. Gaynes, Teena McGuinness, Evelyn B. Quinlivan, Michelle Ogle, Amy Heine, Nathan M. Thielman, and Brian W. Pence. “Improvements in Depression and Changes in Fatigue: Results from the SLAM DUNC Depression Treatment Trial.” Aids Behav 20, no. 2 (February 2016): 235–42. https://doi.org/10.1007/s10461-015-1242-4.

PMID
26525221
Full Text

Berry, Scott M., Elizabeth A. Petzold, Peter Dull, Nathan M. Thielman, Coleen K. Cunningham, G Ralph Corey, Micah T. McClain, et al. “A response adaptive randomization platform trial for efficient evaluation of Ebola virus treatments: A model for pandemic response.” Clin Trials 13, no. 1 (February 2016): 22–30. https://doi.org/10.1177/1740774515621721.

PMID
26768569
Full Text

Thielman, Nathan M., Coleen K. Cunningham, Christopher Woods, Elizabeth Petzold, Mark Sprenz, and James Russell. “Ebola clinical trials: Five lessons learned and a way forward.” Clin Trials 13, no. 1 (February 2016): 83–86. https://doi.org/10.1177/1740774515619897.

PMID
26768559
Full Text

O’Donnell, Julie K., Bradley N. Gaynes, Stephen R. Cole, Andrew Edmonds, Nathan M. Thielman, E Byrd Quinlivan, Kristen Shirey, Amy D. Heine, Riddhi Modi, and Brian W. Pence. “Ongoing life stressors and suicidal ideation among HIV-infected adults with depression.” J Affect Disord 190 (January 15, 2016): 322–28. https://doi.org/10.1016/j.jad.2015.09.054.

PMID
26544615
Full Text

Stanifer, John W., Elizabeth L. Turner, Joseph R. Egger, Nathan Thielman, Francis Karia, Venance Maro, Kajiru Kilonzo, Uptal D. Patel, and Karen Yeates. “Knowledge, Attitudes, and Practices Associated with Chronic Kidney Disease in Northern Tanzania: A Community-Based Study.” Plos One 11, no. 6 (2016): e0156336. https://doi.org/10.1371/journal.pone.0156336.

PMID
27280584
Full Text

Ramadhani, Habib O., John A. Bartlett, Nathan M. Thielman, Brian W. Pence, Stephen M. Kimani, Venance P. Maro, Mtumwa S. Mwako, et al. “The Effect of Switching to Second-Line Antiretroviral Therapy on the Risk of Opportunistic Infections Among Patients Infected With Human Immunodeficiency Virus in Northern Tanzania.” Open Forum Infect Dis 3, no. 1 (January 2016): ofw018. https://doi.org/10.1093/ofid/ofw018.

PMID
26949717
Full Text

Pence, Brian W., Bradley N. Gaynes, Nathan M. Thielman, Amy Heine, Michael J. Mugavero, Elizabeth L. Turner, and Evelyn B. Quinlivan. “Balancing Contamination and Referral Bias in a Randomized Clinical Trial: An Application of Pseudo-Cluster Randomization.” Am J Epidemiol 182, no. 12 (December 15, 2015): 1039–46. https://doi.org/10.1093/aje/kwv132.

PMID
26628511
Full Text

Ostermann, Jan, Derek S. Brown, Axel Mühlbacher, Bernard Njau, and Nathan Thielman. “Would you test for 5000 Shillings? HIV risk and willingness to accept HIV testing in Tanzania.” Health Econ Rev 5, no. 1 (December 2015): 60. https://doi.org/10.1186/s13561-015-0060-8.

PMID
26285777
Full Text

Pages