P. Murali Doraiswamy, MBBS

Professor of Psychiatry and Behavioral Sciences
Director, Neurocognitive Disorders Program
Professor in Medicine
Faculty Network Member of the Duke Institute for Brain Sciences
Affiliate of the Duke Initiative for Science & Society
Campus mail 3550 Hosp South, Durham, NC 27710

Murali Doraiswamy MBBS FRCP is professor of psychiatry and professor in medicine at the Duke University School of Medicine where he is a highly respected physician neuroscientist at the Duke Institute for Brain Sciences. He specializes in the areas of brain health and personalized medicine and leads a clinical trials unit in developing novel personal diagnostics and therapeutics for cognitive enhancement and mental well-being. Prof Doraiswamy has been an advisor to leading government agencies, businesses and advocacy groups. He has served as the chair of the World Economic Forum’s Global Agenda Council on Brain Research and lectured at leading global forums to advance the forefront of neuroscience research.  Moreover as co-author of a popular book The Alzheimer’s Action Plan and co-author on more than 350 publications, he has received several awards in recognition of his scientific work and his involvement in pivotal landmark trials that have helped develop many modern neurotherapeutics. Additionally, he is a leading advocate for increasing funding for brain and behavioral research to help address great looming challenges in society posed by modern developments in the 21st century. His research has been featured in media outlets such as BBC, The New York Times, Scientific American, The Wall Street Journal, National Public Radio, CBS Evening news, The Dr Oz Show, Oprah, and TIME. He has appeared in acclaimed documentaries such as (Dis)Honesty: The Truth about Lies and Mysteries of the Brain.

  

Education and Training

  • M.B.B.S., University of Madras (India), 1987

Grants

Publications

Sundman, Mark, P Murali Doraiswamy, and Rajendra A. Morey. “Neuroimaging assessment of early and late neurobiological sequelae of traumatic brain injury: implications for CTE.” Front Neurosci 9 (2015): 334. https://doi.org/10.3389/fnins.2015.00334.

PMID
26441507
Full Text

Motter, Jeffrey N., Davangere P. Devanand, P Murali Doraiswamy, and Joel R. Sneed. “Computerized Cognitive Training for Major Depressive Disorder: What's Next?” Front Psychiatry 6 (2015): 137. https://doi.org/10.3389/fpsyt.2015.00137.

PMID
26483706
Full Text

Shpanskaya, Katie S., Kingshuk Roy Choudhury, Christopher Hostage, Kelly R. Murphy, Jeffrey R. Petrella, P Murali Doraiswamy, and P Murali Alzheimer’s Disease Neuroimaging Initiative. “Educational attainment and hippocampal atrophy in the Alzheimer's disease neuroimaging initiative cohort.” J Neuroradiol 41, no. 5 (December 2014): 350–57. https://doi.org/10.1016/j.neurad.2013.11.004.

PMID
24485897
Full Text

Doraiswamy, P Murali, Tatiana Pakhalchuk, Geraldine SanRamon, and Svetlana Rechitsky. “Preimplantation Genetic Diagnosis (PGD) for Familial Alzheimer's Disease Due To PSEN1 Mutation.” In Annals of Neurology, 76:S90–S90. WILEY-BLACKWELL, 2014.

Scholars@Duke

Prescott, Jeffrey W., Arnaud Guidon, P Murali Doraiswamy, Kingshuk Roy Choudhury, Chunlei Liu, Jeffrey R. Petrella, and Jeffrey R. Alzheimer’s Disease Neuroimaging Initiative. “The Alzheimer structural connectome: changes in cortical network topology with increased amyloid plaque burden.” Radiology 273, no. 1 (October 2014): 175–84. https://doi.org/10.1148/radiol.14132593.

PMID
24865310
Full Text

Disabato, Brianne M., Carrie Morris, Jennifer Hranilovich, Gina M. D’Angelo, Gongfu Zhou, Ningying Wu, P Murali Doraiswamy, and Yvette I. Sheline. “Comparison of brain structural variables, neuropsychological factors, and treatment outcome in early-onset versus late-onset late-life depression.” Am J Geriatr Psychiatry 22, no. 10 (October 2014): 1039–46. https://doi.org/10.1016/j.jagp.2013.02.005.

PMID
23768683
Full Text

Doraiswamy, P. M., R. A. Sperling, K. Johnson, E. M. Reiman, T. Z. Wong, M. N. Sabbagh, C. H. Sadowsky, et al. “Florbetapir F 18 amyloid PET and 36-month cognitive decline: a prospective multicenter study.” Mol Psychiatry 19, no. 9 (September 2014): 1044–51. https://doi.org/10.1038/mp.2014.9.

PMID
24614494
Full Text

Zannas, Anthony S., P Murali Doraiswamy, Katie S. Shpanskaya, Kelly R. Murphy, Jeffrey R. Petrella, James R. Burke, and Terence Z. Wong. “Impact of ¹⁸F-florbetapir PET imaging of β-amyloid neuritic plaque density on clinical decision-making.” Neurocase 20, no. 4 (August 2014): 466–73. https://doi.org/10.1080/13554794.2013.791867.

PMID
23672654
Full Text

Keefe, Richard S. E., Shawn M. McClintock, Robert M. Roth, P Murali Doraiswamy, Steven Tiger, and Manisha Madhoo. “Cognitive effects of pharmacotherapy for major depressive disorder: a systematic review.” J Clin Psychiatry 75, no. 8 (August 2014): 864–76. https://doi.org/10.4088/JCP.13r08609.

PMID
25099527
Full Text

Pages