P. Murali Doraiswamy, MBBS

Professor of Psychiatry and Behavioral Sciences
Director, Neurocognitive Disorders Program
Professor in Medicine
Faculty Network Member of the Duke Institute for Brain Sciences
Affiliate of the Duke Initiative for Science & Society
Campus mail 3550 Hosp South, Durham, NC 27710

Murali Doraiswamy MBBS FRCP is professor of psychiatry and professor in medicine at the Duke University School of Medicine where he is a highly respected physician neuroscientist at the Duke Institute for Brain Sciences. He specializes in the areas of brain health and personalized medicine and leads a clinical trials unit in developing novel personal diagnostics and therapeutics for cognitive enhancement and mental well-being. Prof Doraiswamy has been an advisor to leading government agencies, businesses and advocacy groups. He has served as the chair of the World Economic Forum’s Global Agenda Council on Brain Research and lectured at leading global forums to advance the forefront of neuroscience research.  Moreover as co-author of a popular book The Alzheimer’s Action Plan and co-author on more than 350 publications, he has received several awards in recognition of his scientific work and his involvement in pivotal landmark trials that have helped develop many modern neurotherapeutics. Additionally, he is a leading advocate for increasing funding for brain and behavioral research to help address great looming challenges in society posed by modern developments in the 21st century. His research has been featured in media outlets such as BBC, The New York Times, Scientific American, The Wall Street Journal, National Public Radio, CBS Evening news, The Dr Oz Show, Oprah, and TIME. He has appeared in acclaimed documentaries such as (Dis)Honesty: The Truth about Lies and Mysteries of the Brain.

  

Education and Training

  • M.B.B.S., University of Madras (India), 1987

Grants

Publications

Tur-Kaspa, Ilan, Roohi Jeelani, and P Murali Doraiswamy. “Preimplantation genetic diagnosis for inherited neurological disorders.” Nat Rev Neurol 10, no. 7 (July 2014): 417–24. https://doi.org/10.1038/nrneurol.2014.84.

PMID
24866878
Full Text

Gerhard, T., K. Huybrechts, M. Olfson, S. Schneeweiss, W. V. Bobo, P. M. Doraiswamy, D. P. Devanand, et al. “Comparative mortality risks of antipsychotic medications in community-dwelling older adults.” Br J Psychiatry 205, no. 1 (July 2014): 44–51. https://doi.org/10.1192/bjp.bp.112.122499.

PMID
23929443
Full Text

Uflacker, Alice, P Murali Doraiswamy, Svetlana Rechitsky, Tricia See, Michael Geschwind, and Ilan Tur-Kaspa. “Preimplantation genetic diagnosis (PGD) for genetic prion disorder due to F198S mutation in the PRNP gene.” Jama Neurol 71, no. 4 (April 2014): 484–86. https://doi.org/10.1001/jamaneurol.2013.5884.

PMID
24493558
Full Text

Hostage, Christopher A., Kingshuk Roy Choudhury, P. Murali Doraiswamy, Jeffrey R. Petrella, and Jeffrey R. Alzheimer’s Disease Neuroimaging Initiative. “Mapping the effect of the apolipoprotein E genotype on 4-year atrophy rates in an Alzheimer disease-related brain network.” Radiology 271, no. 1 (April 2014): 211–19. https://doi.org/10.1148/radiol.13131041.

PMID
24475827
Full Text

Pelton, Gregory H., Howard Andrews, Steven P. Roose, Sue M. Marcus, Kristina D’Antonio, Hala Husn, Jeffrey R. Petrella, Anthony S. Zannas, P Murali Doraiswamy, and D. P. Devanand. “Donepezil treatment of older adults with cognitive impairment and depression (DOTCODE study): clinical rationale and design.” Contemp Clin Trials 37, no. 2 (March 2014): 200–208. https://doi.org/10.1016/j.cct.2013.11.015.

PMID
24315979
Full Text

Zannas, Anthony S., Yasushi Okuno, and P Murali Doraiswamy. “Cholinesterase inhibitors and Pisa syndrome: a pharmacovigilance study.” Pharmacotherapy 34, no. 3 (March 2014): 272–78. https://doi.org/10.1002/phar.1359.

PMID
24127392
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Rathakrishnan, Bharath Gopal, P Murali Doraiswamy, and Jeffrey R. Petrella. “Science to practice: translating automated brain MRI volumetry in Alzheimer's disease from research to routine diagnostic use in the work-up of dementia.” Front Neurol 4 (January 9, 2014): 216. https://doi.org/10.3389/fneur.2013.00216.

PMID
24409168
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Dugger, Brittany N., Christopher M. Clark, Geidy Serrano, Monica Mariner, Barry J. Bedell, R Edward Coleman, P Murali Doraiswamy, et al. “Neuropathologic heterogeneity does not impair florbetapir-positron emission tomography postmortem correlates.” J Neuropathol Exp Neurol 73, no. 1 (January 2014): 72–80. https://doi.org/10.1097/NEN.0000000000000028.

PMID
24335535
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Ferrer, Isidre, Irene López-González, Margarita Carmona, Laura Arregui, Esther Dalfó, Benjamin Torrejón-Escribano, Roberta Diehl, and Gabor G. Kovacs. “Glial and neuronal tau pathology in tauopathies: characterization of disease-specific phenotypes and tau pathology progression.” J Neuropathol Exp Neurol 73, no. 1 (January 2014): 81–97. https://doi.org/10.1097/NEN.0000000000000030.

PMID
24335532
Full Text

Lampert, Erika J., Kingshuk Roy Choudhury, Christopher A. Hostage, Bharath Rathakrishnan, Michael Weiner, Jeffrey R. Petrella, P Murali Doraiswamy, and P Murali Alzheimer’s Disease Neuroimaging Initiative. “Brain atrophy rates in first degree relatives at risk for Alzheimer's.” Neuroimage Clin 6 (2014): 340–46. https://doi.org/10.1016/j.nicl.2014.08.024.

PMID
25379448
Full Text

Pages