Phillip James White, PhD

Assistant Professor in Medicine
Member of Duke Molecular Physiology Institute
Email address phillip.white@duke.edu

Phillip White is an Assistant Professor in the Department of Medicine, Division of Endocrinology, Metabolism and Nutrition. Phillip Co-Leads the White-McGarrah Lab with Robert McGarrah at the Duke Molecular Physiology Institue. Projects in the White-McGarrah Lab relate to the integrative physiology of metabolism with an emphasis on liver and heart function and the metabolic crosstalk that exists between these two vital organs.

Education and Training

  • Ph.D., Universite Laval (Canada), 2012

Publications

Ericksen, RE, Lim, SL, McDonnell, E, Shuen, WH, Vadiveloo, M, White, PJ, Ding, Z, Kwok, R, Lee, P, Radda, GK, Toh, HC, Hirschey, MD, and Han, W. "Loss of BCAA Catabolism during Carcinogenesis Enhances mTORC1 Activity and Promotes Tumor Development and Progression." Cell Metabolism 29, no. 5 (May 2019): 1151-1165.e6.

PMID
30661928
Full Text

White, PJ, and Newgard, CB. "Branched-chain amino acids in disease." Science (New York, N.Y.) 363, no. 6427 (February 2019): 582-583.

PMID
30733403
Full Text

White, PJ, McGarrah, RW, Grimsrud, PA, Tso, S-C, Yang, W-H, Haldeman, JM, Grenier-Larouche, T, An, J, Lapworth, AL, Astapova, I, Hannou, SA, George, T, Arlotto, M, Olson, LB, Lai, M, Zhang, G-F, Ilkayeva, O, Herman, MA, Wynn, RM, Chuang, DT, and Newgard, CB. "The BCKDH Kinase and Phosphatase Integrate BCAA and Lipid Metabolism via Regulation of ATP-Citrate Lyase." Cell Metabolism 27, no. 6 (June 2018): 1281-1293.e7.

PMID
29779826
Full Text

Gurley, JM, Ilkayeva, O, Jackson, RM, Griesel, BA, White, P, Matsuzaki, S, Qaisar, R, Van Remmen, H, Humphries, KM, Newgard, CB, and Olson, AL. "Enhanced GLUT4-Dependent Glucose Transport Relieves Nutrient Stress in Obese Mice Through Changes in Lipid and Amino Acid Metabolism." Diabetes 65, no. 12 (December 2016): 3585-3597.

PMID
27679559
Full Text

White, PJ, Lapworth, AL, An, J, Wang, L, McGarrah, RW, Stevens, RD, Ilkayeva, O, George, T, Muehlbauer, MJ, Bain, JR, Trimmer, JK, Brosnan, MJ, Rolph, TP, and Newgard, CB. "Branched-chain amino acid restriction in Zucker-fatty rats improves muscle insulin sensitivity by enhancing efficiency of fatty acid oxidation and acyl-glycine export." Molecular Metabolism 5, no. 7 (July 2016): 538-551.

PMID
27408778
Full Text

Vandal, M, White, PJ, Tournissac, M, Tremblay, C, St-Amour, I, Drouin-Ouellet, J, Bousquet, M, Traversy, M-T, Planel, E, Marette, A, and Calon, F. "Impaired thermoregulation and beneficial effects of thermoneutrality in the 3×Tg-AD model of Alzheimer's disease." Neurobiology of Aging 43 (July 2016): 47-57.

PMID
27255814
Full Text

Glynn, EL, Piner, LW, Huffman, KM, Slentz, CA, Elliot-Penry, L, AbouAssi, H, White, PJ, Bain, JR, Muehlbauer, MJ, Ilkayeva, OR, Stevens, RD, Porter Starr, KN, Bales, CW, Volpi, E, Brosnan, MJ, Trimmer, JK, Rolph, TP, Newgard, CB, and Kraus, WE. "Impact of combined resistance and aerobic exercise training on branched-chain amino acid turnover, glycine metabolism and insulin sensitivity in overweight humans." Diabetologia 58, no. 10 (October 2015): 2324-2335.

PMID
26254576
Full Text

Vandal, M, White, PJ, Chevrier, G, Tremblay, C, St-Amour, I, Planel, E, Marette, A, and Calon, F. "Age-dependent impairment of glucose tolerance in the 3xTg-AD mouse model of Alzheimer's disease." Faseb Journal : Official Publication of the Federation of American Societies for Experimental Biology 29, no. 10 (October 2015): 4273-4284.

PMID
26108977
Full Text

White, PJ, Mitchell, PL, Schwab, M, Trottier, J, Kang, JX, Barbier, O, and Marette, A. "Transgenic ω-3 PUFA enrichment alters morphology and gene expression profile in adipose tissue of obese mice: Potential role for protectins." Metabolism: Clinical and Experimental 64, no. 6 (June 2015): 666-676.

PMID
25726444
Full Text

White, PJ, Mitchell, PL, Schwab, M, Trottier, J, Kang, JX, Barbier, O, and Marette, A. "Erratum: Transgenic ω -3 PUFA enrichment alters morphology and gene expression profile in adipose tissue of obese mice: Potential role for protectins (Metab Clin Exp (2015): 64 (666-676))." Metabolism: Clinical and Experimental 64, no. 9 (January 1, 2015): E7-E8.

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