Rebekah Ryanne Wu, MD

Associate Professor of Medicine
Member of Duke Center for Applied Genomics and Precision Medicine
Campus mail 304 Research Drive, Box 90141, Durham, NC 27708
Phone (919) 684-5479
Email address ryanne.wu@duke.edu

Dr. Wu is an internal medicine physician and health services researcher. Her main research interest is studying the implementation of precision medicine applications to improve clinical care. She is involved in projects currently looking at a patient-facing family history risk assessment tool, MeTree, which provides individualized risk stratification and clinical decision support recommendations to clinicians and patients. In addition she is also involved in a large scale sequencing program in Singapore looking at the intersection of family health history and genomics to better understand how these data elements can complement one another and create more precise risk predictions.  She is a member of NHGRI's IGNITE network as a co-investigator on a multi-site pragmatic clinical trial of the impact of pharmacogenetic testing on management of depression and acute, and chronic pain.  She is the implementation science advisor for the VA's Pharmacogenomic Testing for Veterans (PHASER) program, which is working to complete preemptive PGx testing on up to 250,000 Veterans by 2024.

Education and Training

  • Chief Resident, Internal Medicine, Georgetown University School of Medicine, 2009 - 2010
  • Resident, Internal Medicine, Georgetown University School of Medicine, 2006 - 2009
  • M.D., University of North Carolina, Chapel Hill, School of Medicine, 2006

Publications

Wu, R Ryanne, Linda S. Kinsinger, Dawn Provenzale, Heather A. King, Patricia Akerly, Lottie K. Barnes, Santanu K. Datta, et al. “Implementation of new clinical programs in the VHA healthcare system: the importance of early collaboration between clinical leadership and research.” J Gen Intern Med 29 Suppl 4 (December 2014): 825–30. https://doi.org/10.1007/s11606-014-3026-3.

PMID
25355086
Full Text

Beadles, Chris A., R. Ryanne Wu, Tiffany Himmel, Adam H. Buchanan, Karen P. Powell, Elizabeth Hauser, Vincent C. Henrich, Geoffrey S. Ginsburg, and Lori A. Orlando. “Providing patient education: impact on quantity and quality of family health history collection.” Fam Cancer 13, no. 2 (June 2014): 325–32. https://doi.org/10.1007/s10689-014-9701-z.

PMID
24515581
Full Text

Orlando, Lori A., R Ryanne Wu, Chris Beadles, Tiffany Himmel, Adam H. Buchanan, Karen P. Powell, Elizabeth R. Hauser, Vincent C. Henrich, and Geoffrey S. Ginsburg. “Implementing family health history risk stratification in primary care: impact of guideline criteria on populations and resource demand.” Am J Med Genet C Semin Med Genet 166C, no. 1 (March 2014): 24–33. https://doi.org/10.1002/ajmg.c.31388.

PMID
24616329
Full Text

Wu, R Ryanne, Tiffany L. Himmel, Adam H. Buchanan, Karen P. Powell, Elizabeth R. Hauser, Geoffrey S. Ginsburg, Vincent C. Henrich, and Lori A. Orlando. “Quality of family history collection with use of a patient facing family history assessment tool.” Bmc Fam Pract 15 (February 13, 2014): 31. https://doi.org/10.1186/1471-2296-15-31.

PMID
24520818
Full Text

Wu, R. R., T. L. Himmel, A. H. Buchanan, K. P. Powell, E. R. Hauser, G. S. Ginsburg, V. C. Henrich, and L. A. Orlando. “Quality of family history collection with use of a patient facing family history assessment tool.” Bmc Family Practice 15, no. 1 (2014). https://doi.org/10.1186/1471-2296-15-31.

Full Text

Wu, R Ryanne, Lori A. Orlando, Tiffany L. Himmel, Adam H. Buchanan, Karen P. Powell, Elizabeth R. Hauser, Astrid B. Agbaje, Vincent C. Henrich, and Geoffrey S. Ginsburg. “Patient and primary care provider experience using a family health history collection, risk stratification, and clinical decision support tool: a type 2 hybrid controlled implementation-effectiveness trial.” Bmc Fam Pract 14 (August 6, 2013): 111. https://doi.org/10.1186/1471-2296-14-111.

PMID
23915256
Full Text

Wu, Rebekah R., Tiffany Himmel, Adam Buchanan, Karen Powell, Elizabeth Hauser, Astrid B. Agbaje, Geoffrey S. Ginsburg, Vincent Henrich, and Lori A. Orlando. “IMPACT OF A FAMILY HISTORY COLLECTION TOOL, METREE (c), IN IDENTIFYING INDIVIDUALS AT HIGH-RISK FOR CANCER AND THROMBOSIS.” In Journal of General Internal Medicine, 28:S101–S101. SPRINGER, 2013.

Scholars@Duke

Wu, Rebekah R., Tiffany Himmel, Karen Powell, Elizabeth Hauser, Astrid B. Agbaje, Vincent Henrich, Geoffrey S. Ginsburg, and Lori A. Orlando. “USABILITY OF A FAMILY HEALTH HISTORY AND CLINICAL DECISION SUPPORT TOOL FOR PATIENTS AND PRIMARY CARE PROVIDERS.” In Journal of General Internal Medicine, 28:S233–S233. SPRINGER, 2013.

Scholars@Duke

Wu, R. R., T. Himmel, K. Powell, E. Hauser, A. Agbaje, G. Ginsburg, V. Henrich, and L. Orlando. “USABILITYOF A FAMILY HEALTH HISTORY AND CLINICAL DECISION SUPPORT TOOL FOR PATIENTS AND PRIMARY CARE PROVIDERS.” In Journal of Investigative Medicine, 61:523–523. LIPPINCOTT WILLIAMS & WILKINS, 2013.

Scholars@Duke

Sun, J. F., R. R. Wu, C. Norris, A. M. Noone, M. Amankwa-Sakyi, R. Slack, and J. L. Marshall. “Safety of chronic low-dose capecitabine as maintenance therapy in gastrointestinal cancers.” Gastrointestinal Cancer Research 3, no. 4 (July 1, 2010): 134–40.

Scholars@Duke

Pages