Robert John Mentz, MD

Associate Professor of Medicine
Associate Professor in Population Health Sciences
Member in the Duke Clinical Research Institute
Campus mail Np-8062, Dcri. PO Box 17969, Durham, NC 27715
Phone (919) 668-7121
Email address

I am a cardiologist with a clinical and research interest in heart failure, including advanced therapies such as cardiac transplantation and mechanical assist devices or “heart pumps." I became a heart failure cardiologist in order to help patients manage their chronic disease over many months and years. I consider myself strongly committed to compassionate patient care with a focus on quality of life and patient preference.

My research interests are focused on treating co-morbid diseases in heart failure patients and improving outcomes across the cardiovascular spectrum through clinical trials and outcomes research. Below, you will find my specific research interests:

  •     Co-morbidity characterization (diabetes, sleep apnea, renal failure) in heart failure.
  •     Phenotypic characterization and risk prognostication of patients with heart failure.
  •     Role of surrogate and nonfatal endpoints in clinical heart failure trials.
  •     Biomarkers in heart failure.
  •     Novel pharmacological and non-pharmacological approaches to heart failure.
  •     Improving site-based heart failure research.
In Their Words

Education and Training

  • Fellowship, Advanced Heart Failure, Duke University School of Medicine, 2012 - 2013
  • Fellowship, Clinical Cardiology, Duke University School of Medicine, 2010 - 2012
  • Resident, Internal Medicine, Brigham and Women's Hospital, 2008 - 2010
  • Intern, Internal Medicine, Brigham and Women's Hospital, 2007 - 2008
  • M.D., Emory University, 2003


Cerbin, Lukasz P., Andrew P. Ambrosy, and Robert J. Mentz. “Reply: Factors That May Affect Body Change During and After Hospitalization for Acute Heart Failure..” Jacc Heart Fail 5, no. 4 (April 2017): 311–12.

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Cooper, Lauren Beth, Lina Benson, Robert Mentz, Gianluigi Savarese, Adam DeVore, Juan Jesus Carrero, Ulf Dahlstrom, et al. “ASSOCIATION BETWEEN SERUM POTASSIUM LEVEL AND OUTCOMES IN HEART FAILURE WITH REDUCED EJECTION FRACTION: A COHORT STUDY FROM THE SWEDISH HEART FAILURE REGISTRY.” In Journal of the American College of Cardiology, 69:678–678. ELSEVIER SCIENCE INC, 2017.


Fudim, Marat, Andrew Ambrosy, Allison Dunning, Randall Starling, Justin Ezekowitz, Paul Armstrong, Marco Metra, et al. “TIMING AND CLINICAL PREDICTORS OF EARLY VERSUS LATE READMISSION AMONG PATIENTS HOSPITALIZED FOR ACUTE HEART FAILURE: INSIGHTS FROM ASCEND-HF.” In Journal of the American College of Cardiology, 69:766–766. ELSEVIER SCIENCE INC, 2017.


Greene, Stephen, G Michael Felker, Jie Sun, Andrew Ambrosy, Bradley Bart, Javed Butler, Adam DeVore, et al. “HEMOCONCENTRATION DURING MANAGEMENT OF PATIENTS WITH ACUTE HEART FAILURE AND CARDIORENAL SYNDROME: INSIGHTS FROM CARRESS-HF.” In Journal of the American College of Cardiology, 69:767–767. ELSEVIER SCIENCE INC, 2017.


Ambrosy, Andrew P., Ankeet Bhatt, Amanda Stebbins, Lisa Wruck, Stephen Greene, Marat Fudim, William Kraus, et al. “PREVALENT DIGOXIN USE IS NOT ASSOCIATED WITH INCREASED RISK OF DEATH OR HOSPITALIZATION IN AMBULATORY HEART FAILURE PATIENTS WITH A REDUCED EJECTION FRACTION.” In Journal of the American College of Cardiology, 69:676–676. ELSEVIER SCIENCE INC, 2017.


Felker, G Michael, Robert J. Mentz, Robert T. Cole, Kirkwood F. Adams, Gregory F. Egnaczyk, Mona Fiuzat, Chetan B. Patel, et al. “Efficacy and Safety of Tolvaptan in Patients Hospitalized With Acute Heart Failure..” J Am Coll Cardiol 69, no. 11 (March 21, 2017): 1399–1406.

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Randolph, Tiffany C., Samuel Broderick, Linda K. Shaw, Karen Chiswell, Robert J. Mentz, Valentina Kutyifa, Eric J. Velazquez, Francis R. Gilliam, and Kevin L. Thomas. “Race and Sex Differences in QRS Interval and Associated Outcome Among Patients with Left Ventricular Systolic Dysfunction..” J Am Heart Assoc 6, no. 3 (March 20, 2017).

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Bhatt, Ankeet S., Adam D. DeVore, Adrian F. Hernandez, and Robert J. Mentz. “Can Vaccinations Improve Heart Failure Outcomes? Contemporary Data and Future Directions.” Jacc Heart Failure 5, no. 3 (March 1, 2017): 195–203.


Reeves, Gordon R., David J. Whellan, Pamela Duncan, Christopher M. O’Connor, Amy M. Pastva, Joel D. Eggebeen, Leigh Ann Hewston, et al. “Rehabilitation Therapy in Older Acute Heart Failure Patients (REHAB-HF) trial: Design and rationale..” Am Heart J 185 (March 2017): 130–39.

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