Robert M. Califf

Professor of Medicine
Donald F. Fortin, M.D. Professor of Cardiology, in the School of Medicine
Member of the Duke Clinical Research Institute
Campus mail 100 Trent Drive, Suite401, Davison Building, Durham, NC 27710
Phone (919) 668-9222
Email address robert.califf@duke.edu

Robert Califf, MD MACC, is the Donald F. Fortin, MD, Professor of Cardiology. He is also Professor of Medicine in the Division of Cardiology and remains a practicing cardiologist. Dr. Califf was the Commissioner of Food and Drugs in 2016-2017 and  Deputy Commissioner for Medical Products and Tobacco from February 2015 until his appointment as Commissioner in February 2016. Prior to joining the FDA, Dr. Califf was a professor of medicine and vice chancellor for clinical and translational research at Duke University. He also served as director of the Duke Translational Medicine Institute and founding director of the Duke Clinical Research Institute. A nationally and internationally recognized expert in cardiovascular medicine, health outcomes research, healthcare quality, and clinical research, Dr. Califf has led many landmark clinical trials and is one of the most frequently cited authors in biomedical science, with more than 1,200 publications in the peer-reviewed literature.

Dr. Califf is a Member of the National Academy of Medicine (formerly known as the Institute of Medicine (IOM)) in 2016, one of the highest honors in the fields of health and medicine. Dr. Califf has served on numerous IOM committees, and he has served as a member of the FDA Cardiorenal Advisory Panel and FDA Science Board's Subcommittee on Science and Technology. Dr. Califf has also served on the Board of Scientific Counselors for the National Library of Medicine, as well as on advisory committees for the National Cancer Institute, the National Heart, Lung, and Blood Institute, the National Institute of Environmental Health Sciences and the Council of the National Institute on Aging.

He has led major initiatives aimed at improving methods and infrastructure for clinical research, including the Clinical Trials Transformation Initiative (CTTI), a public-private partnership co-founded by the FDA and Duke. He also served as the principal investigator for Duke's Clinical and Translational Science Award and the NIH Health Care Systems Research Collaboratory coordinating center and co-PI of the Patient Centered Outcomes Research Institute Network.

Associated Faculty Labs

Publications

Califf, RM, and Harrell, FE. "Individual risk prediction using data beyond the medical clinic." Cmaj : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne 190, no. 32 (August 2018): E947-E948.

PMID
30104187
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Aronson, S. "In Response." Anesthesia and Analgesia 127, no. 1 (July 2018): 317-318.

PMID
29734242
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Califf, RM. "Mass Customization, Ubiquitous Information, and Improvements to Health Outcomes in the United States." Jama Cardiology 3, no. 5 (May 2018): 365-366.

PMID
29516101
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Yang, JD, AbdelmaleK, MF, Guy, CD, Diehl, AM, and Suzuki, A. "Reply(Accepted)." Clinical Gastroenterology and Hepatology (January 1, 2017).

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Granieri, MA, Webster, GD, and Peterson, AC. "Author Reply." Urology 91 (May 2016): 207-null. (Letter)

PMID
27083938
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Partin, MR, Shaukat, A, Nelson, DB, Gravely, A, Nugent, S, Gellad, ZF, and Burgess, JF. "Reply." Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association 14, no. 3 (March 2016): 486-null. (Letter)

PMID
26689898
Full Text

Selker, HP, Buse, JB, Califf, RM, Carter, R, Cooper, DM, Davis, J, Ford, DE, Galassetti, P, Guay-Woodford, L, Huggins, GS, Kasper, A, Kieburtz, K, Kirby, A, Klein, AK, Kline, J, O' Neill, RT, Rape, M, Reichgott, DJ, Rojevsky, S, Rosenthal, GE, Rubinstein, EP, Shepherd, A, Stacy, M, Terrin, N, Wallace, M, and Welch, L. "CTSA Consortium Consensus Scientific Review Committee (SRC) Working Group Report on the SRC Processes." Clinical and Translational Science 8, no. 6 (December 2015): 623-631.

PMID
26184433
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Preiss, D, Thomas, LE, Wojdyla, DM, Haffner, SM, Gill, JMR, Yates, T, Davies, MJ, Holman, RR, McMurray, JJ, Califf, RM, Kraus, WE, and NAVIGATOR Investigators, . "Prospective relationships between body weight and physical activity: an observational analysis from the NAVIGATOR study." Bmj Open 5, no. 8 (August 14, 2015): e007901-null.

PMID
26275900
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Yates, T, Davies, MJ, Haffner, SM, Schulte, PJ, Thomas, L, Huffman, KM, Bales, CW, Preiss, D, Califf, RM, Holman, RR, McMurray, JJV, Bethel, MA, Tuomilehto, J, and Kraus, WE. "Physical activity as a determinant of fasting and 2-h post-challenge glucose: a prospective cohort analysis of the NAVIGATOR trial." Diabetic Medicine : a Journal of the British Diabetic Association 32, no. 8 (August 2015): 1090-1096.

PMID
25818859
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Kelly, JP, Mentz, RJ, Hasselblad, V, Ezekowitz, JA, Armstrong, PW, Zannad, F, Felker, GM, Califf, RM, O'Connor, CM, and Hernandez, AF. "Worsening heart failure during hospitalization for acute heart failure: Insights from the Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure (ASCEND-HF)." American Heart Journal 170, no. 2 (August 2015): 298-305.

PMID
26299227
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