Robert M. Califf

Professor of Medicine
Donald F. Fortin, M.D. Professor of Cardiology, in the School of Medicine
Member of the Duke Clinical Research Institute
Campus mail 100 Trent Drive, Suite401, Davison Building, Durham, NC 27710
Phone (919) 668-9222
Email address robert.califf@duke.edu

Robert Califf, MD MACC, is the Donald F. Fortin, MD, Professor of Cardiology. He is also Professor of Medicine in the Division of Cardiology and remains a practicing cardiologist. Dr. Califf was the Commissioner of Food and Drugs in 2016-2017 and  Deputy Commissioner for Medical Products and Tobacco from February 2015 until his appointment as Commissioner in February 2016. Prior to joining the FDA, Dr. Califf was a professor of medicine and vice chancellor for clinical and translational research at Duke University. He also served as director of the Duke Translational Medicine Institute and founding director of the Duke Clinical Research Institute. A nationally and internationally recognized expert in cardiovascular medicine, health outcomes research, healthcare quality, and clinical research, Dr. Califf has led many landmark clinical trials and is one of the most frequently cited authors in biomedical science, with more than 1,200 publications in the peer-reviewed literature.

Dr. Califf is a Member of the National Academy of Medicine (formerly known as the Institute of Medicine (IOM)) in 2016, one of the highest honors in the fields of health and medicine. Dr. Califf has served on numerous IOM committees, and he has served as a member of the FDA Cardiorenal Advisory Panel and FDA Science Board's Subcommittee on Science and Technology. Dr. Califf has also served on the Board of Scientific Counselors for the National Library of Medicine, as well as on advisory committees for the National Cancer Institute, the National Heart, Lung, and Blood Institute, the National Institute of Environmental Health Sciences and the Council of the National Institute on Aging.

He has led major initiatives aimed at improving methods and infrastructure for clinical research, including the Clinical Trials Transformation Initiative (CTTI), a public-private partnership co-founded by the FDA and Duke. He also served as the principal investigator for Duke's Clinical and Translational Science Award and the NIH Health Care Systems Research Collaboratory coordinating center and co-PI of the Patient Centered Outcomes Research Institute Network.

Associated Faculty Labs

Publications

Bates, E. R., R. M. Califf, R. S. Stack, L. Aronson, B. S. George, R. J. Candela, D. J. Kereiakes, C. W. Abbottsmith, L. Anderson, and B. Pitt. “Thrombolysis and Angioplasty in Myocardial Infarction (TAMI-1) trial: influence of infarct location on arterial patency, left ventricular function and mortality..” Journal of the American College of Cardiology 13, no. 1 (January 1989): 12–18. https://doi.org/10.1016/0735-1097(89)90542-1.

PMID
2521226
Full Text

Hlatky, M. A., D. B. Mark, R. M. Califf, and D. B. Pryor. “Angina, myocardial ischemia and coronary disease: gold standards, operational definitions and correlations..” Journal of Clinical Epidemiology 42, no. 5 (January 1989): 381–84. https://doi.org/10.1016/0895-4356(89)90125-x.

PMID
2732766
Full Text

Gersh, B. J., R. M. Califf, F. D. Loop, C. W. Akins, D. B. Pryor, and T. C. Takaro. “Coronary bypass surgery in chronic stable angina.” Circulation 79, no. 6 SUPPL. (1989).

Scholars@Duke

Topol, E. J., R. M. Califf, B. S. George, D. J. Kereiakes, and K. L. Lee. “Insights derived from the thrombolysis and angioplasty in myocardial infarction (TAMI) trials..” Journal of the American College of Cardiology 12, no. 6 Suppl A (December 1988): 24A-31A. https://doi.org/10.1016/0735-1097(88)92638-1.

PMID
2973486
Full Text

Mark, D. B., M. A. Hlatky, C. M. O’Connor, D. B. Pryor, T. C. Wall, M. B. Honan, H. R. Phillips, and R. M. Califf. “Administration of thrombolytic therapy in the community hospital: established principles and unresolved issues..” Journal of the American College of Cardiology 12, no. 6 Suppl A (December 1988): 32A-43A. https://doi.org/10.1016/0735-1097(88)92639-3.

PMID
2973487
Full Text

Califf, R. M., S. Mantell, C. Westawski, W. Bride, M. B. Honan, R. L. Bellinger, and T. C. Wall. “Experience with the use of tPA in the treatment of acute myocardial infarction..” Annals of Emergency Medicine 17, no. 11 (November 1988): 1176–89. https://doi.org/10.1016/s0196-0644(88)80064-7.

PMID
2973270
Full Text

Stack, R. S., R. M. Califf, H. R. Phillips, D. B. Pryor, P. J. Quigley, R. P. Bauman, J. E. Tcheng, and J. C. Greenfield. “Interventional cardiac catheterization at Duke Medical Center..” The American Journal of Cardiology 62, no. 10 Pt 2 (October 1988): 3F-24F.

PMID
2972185
Scholars@Duke

Califf, R. M., E. J. Topol, B. S. George, J. M. Boswick, C. Abbottsmith, K. N. Sigmon, R. Candela, R. Masek, D. Kereiakes, and W. W. O’Neill. “Hemorrhagic complications associated with the use of intravenous tissue plasminogen activator in treatment of acute myocardial infarction..” The American Journal of Medicine 85, no. 3 (September 1988): 353–59. https://doi.org/10.1016/0002-9343(88)90586-4.

PMID
3137818
Full Text

Munster, M., and R. M. Califf. “Heart attack..” North Carolina Medical Journal 49, no. 9 (September 1988): 441–44.

PMID
3185760
Scholars@Duke

Hickey, M. S., L. R. Smith, L. H. Muhlbaier, F. E. Harrell, J. G. Reves, T. Hinohara, R. M. Califf, D. B. Pryor, and J. S. Rankin. “Current prognosis of ischemic mitral regurgitation. Implications for future management..” Circulation 78, no. 3 Pt 2 (September 1988): I51–59.

PMID
2970346
Scholars@Duke

Pages