Robert M. Califf

Professor of Medicine
Donald F. Fortin, M.D. Professor of Cardiology, in the School of Medicine
Member of the Duke Clinical Research Institute
Campus mail 100 Trent Drive, Suite401, Davison Building, Durham, NC 27710
Phone (919) 668-9222
Email address robert.califf@duke.edu

Robert Califf, MD MACC, is the Donald F. Fortin, MD, Professor of Cardiology. He is also Professor of Medicine in the Division of Cardiology and remains a practicing cardiologist. Dr. Califf was the Commissioner of Food and Drugs in 2016-2017 and  Deputy Commissioner for Medical Products and Tobacco from February 2015 until his appointment as Commissioner in February 2016. Prior to joining the FDA, Dr. Califf was a professor of medicine and vice chancellor for clinical and translational research at Duke University. He also served as director of the Duke Translational Medicine Institute and founding director of the Duke Clinical Research Institute. A nationally and internationally recognized expert in cardiovascular medicine, health outcomes research, healthcare quality, and clinical research, Dr. Califf has led many landmark clinical trials and is one of the most frequently cited authors in biomedical science, with more than 1,200 publications in the peer-reviewed literature.

Dr. Califf is a Member of the National Academy of Medicine (formerly known as the Institute of Medicine (IOM)) in 2016, one of the highest honors in the fields of health and medicine. Dr. Califf has served on numerous IOM committees, and he has served as a member of the FDA Cardiorenal Advisory Panel and FDA Science Board's Subcommittee on Science and Technology. Dr. Califf has also served on the Board of Scientific Counselors for the National Library of Medicine, as well as on advisory committees for the National Cancer Institute, the National Heart, Lung, and Blood Institute, the National Institute of Environmental Health Sciences and the Council of the National Institute on Aging.

He has led major initiatives aimed at improving methods and infrastructure for clinical research, including the Clinical Trials Transformation Initiative (CTTI), a public-private partnership co-founded by the FDA and Duke. He also served as the principal investigator for Duke's Clinical and Translational Science Award and the NIH Health Care Systems Research Collaboratory coordinating center and co-PI of the Patient Centered Outcomes Research Institute Network.

Associated Faculty Labs

Publications

Simonton, CA, Mark, DB, Hinohara, T, Rendall, DS, Phillips, HR, Peter, RH, Behar, VS, Kong, Y, O'Callaghan, WG, and O'Connor, C. "Late restenosis after emergent coronary angioplasty for acute myocardial infarction: comparison with elective coronary angioplasty." Journal of the American College of Cardiology 11, no. 4 (April 1988): 698-705.

PMID
2965171
Full Text

Hlatky, MA, Cotugno, HE, Mark, DB, O'Connor, C, Califf, RM, and Pryor, DB. "Trends in physician management of uncomplicated acute myocardial infarction, 1970 to 1987." The American Journal of Cardiology 61, no. 8 (March 1988): 515-518.

PMID
3344676
Full Text

Hlatky, MA, Cotugno, H, O'Connor, C, Mark, DB, Pryor, DB, and Califf, RM. "Adoption of thrombolytic therapy in the management of acute myocardial infarction." The American Journal of Cardiology 61, no. 8 (March 1988): 510-514.

PMID
3125736
Full Text

"Thrombolysis and angioplasty in acute myocardial infarction." The New England Journal of Medicine 318, no. 9 (March 1988): 576-579. (Letter)

PMID
2963215
Full Text

Rankin, JS, Feneley, MP, Hickey, MS, Muhlbaier, LH, Wechsler, AS, Floyd, RD, Reves, JG, Skelton, TN, Califf, RM, and Lowe, JE. "A clinical comparison of mitral valve repair versus valve replacement in ischemic mitral regurgitation." The Journal of Thoracic and Cardiovascular Surgery 95, no. 2 (February 1988): 165-177.

PMID
3276968
Scholars@Duke

Hlatky, MA, Califf, RM, Harrell, FE, Lee, KL, Mark, DB, and Pryor, DB. "Comparison of predictions based on observational data with the results of randomized controlled clinical trials of coronary artery bypass surgery." Journal of the American College of Cardiology 11, no. 2 (February 1988): 237-245.

PMID
3276752
Full Text

Bounous, EP, Mark, DB, Pollock, BG, Hlatky, MA, Jr, FEH, Lee, KL, Rankin, JS, Wechsler, AS, Pryor, DB, and Califf, RM. "Surgical survival benefits for coronary disease patients with left ventricular dysfunction." Circulation 78, no. 3 II SUPPL. (1988): I-151-I-157-null.

Scholars@Duke

Topol, EJ, Califf, RM, George, BS, Kereiakes, DJ, and Lee, KL. "Insights derived from the Thrombolysis and Angioplasty in Myocardial Infarction (TAMI) trials." Journal of the American College of Cardiology 12, no. 6 SUPPL. A (January 1, 1988).

Full Text

Stack, RS, Califf, RM, Phillips, HR, Pryor, DB, Quigley, PJ, Bauman, RP, Tcheng, JE, and Greenfield, JC. "Interventional Cardiac Catheterization at Duke Medical Center - The Duke Interventional Cardiac Catheterization Program." American Journal of Cardiology 62, no. 10 PART II (January 1, 1988). (Review)

Scholars@Duke

Stack, RS, Califf, RM, Phillips, HR, Pryor, DB, Quigley, PJ, Bauman, RP, Tcheng, JE, and Greenfield, JC. "New international technology: The autoperfusion balloon catheter." American Journal of Cardiology 62, no. 10 PART II (January 1, 1988).

Scholars@Duke

Pages