Robert M. Califf

Professor of Medicine
Donald F. Fortin, M.D. Professor of Cardiology, in the School of Medicine
Member of the Duke Clinical Research Institute
Campus mail 100 Trent Drive, Suite401, Davison Building, Durham, NC 27710
Phone (919) 668-9222
Email address robert.califf@duke.edu

Robert Califf, MD MACC, is the Donald F. Fortin, MD, Professor of Cardiology. He is also Professor of Medicine in the Division of Cardiology and remains a practicing cardiologist. Dr. Califf was the Commissioner of Food and Drugs in 2016-2017 and  Deputy Commissioner for Medical Products and Tobacco from February 2015 until his appointment as Commissioner in February 2016. Prior to joining the FDA, Dr. Califf was a professor of medicine and vice chancellor for clinical and translational research at Duke University. He also served as director of the Duke Translational Medicine Institute and founding director of the Duke Clinical Research Institute. A nationally and internationally recognized expert in cardiovascular medicine, health outcomes research, healthcare quality, and clinical research, Dr. Califf has led many landmark clinical trials and is one of the most frequently cited authors in biomedical science, with more than 1,200 publications in the peer-reviewed literature.

Dr. Califf is a Member of the National Academy of Medicine (formerly known as the Institute of Medicine (IOM)) in 2016, one of the highest honors in the fields of health and medicine. Dr. Califf has served on numerous IOM committees, and he has served as a member of the FDA Cardiorenal Advisory Panel and FDA Science Board's Subcommittee on Science and Technology. Dr. Califf has also served on the Board of Scientific Counselors for the National Library of Medicine, as well as on advisory committees for the National Cancer Institute, the National Heart, Lung, and Blood Institute, the National Institute of Environmental Health Sciences and the Council of the National Institute on Aging.

He has led major initiatives aimed at improving methods and infrastructure for clinical research, including the Clinical Trials Transformation Initiative (CTTI), a public-private partnership co-founded by the FDA and Duke. He also served as the principal investigator for Duke's Clinical and Translational Science Award and the NIH Health Care Systems Research Collaboratory coordinating center and co-PI of the Patient Centered Outcomes Research Institute Network.

Associated Faculty Labs

Publications

Stack, R. S., R. M. Califf, H. R. Phillips, D. B. Pryor, P. J. Quigley, R. P. Bauman, J. E. Tcheng, and J. C. G. Jr. “Balloon angioplasty in acute myocardial infarction - Limitations of thrombolytic therapy when used alone.” American Journal of Cardiology 62, no. 10 PART II (1988): 4F-4F.

Scholars@Duke

Bounous, E. P., D. B. Mark, B. G. Pollock, M. A. Hlatky, F. E. H. Jr, K. L. Lee, J. S. Rankin, A. S. Wechsler, D. B. Pryor, and R. M. Califf. “Surgical survival benefits for coronary disease patients with left ventricular dysfunction.” Circulation 78, no. 3 II SUPPL. (1988).

Scholars@Duke

Boswick, J. M., K. L. Lee, L. G. Aronson, C. M. O’Connor, M. B. Honan, R. M. Califf, and D. B. Pryor. “USE OF COMPUTERIZED STATISTICAL MODELS TO EDUCATE MEDICAL HOUSESTAFF IN ESTIMATING CLINICAL OUTCOMES..” Proceedings  Annual Symposium on Computer Applications in Medical Care, December 1, 1987, 162–65.

Scholars@Duke

Topol, E. J., R. M. Califf, D. J. Kereiakes, and B. S. George. “Thrombolysis and Angioplasty in Myocardial Infarction (TAMI) trial..” J Am Coll Cardiol 10, no. 5 Suppl B (November 1987): 65B-74B.

PMID
2959716
Scholars@Duke

Pryor, D. B., F. E. Harrell, J. S. Rankin, K. L. Lee, L. H. Muhlbaier, H. N. Oldham, M. A. Hlatky, D. B. Mark, J. G. Reves, and R. M. Califf. “The changing survival benefits of coronary revascularization over time..” Circulation 76, no. 5 Pt 2 (November 1987): V13–21.

PMID
3499256
Scholars@Duke

Slater, D. K., M. A. Hlatky, D. B. Mark, F. E. Harrell, D. B. Pryor, and R. M. Califf. “Outcome in suspected acute myocardial infarction with normal or minimally abnormal admission electrocardiographic findings..” Am J Cardiol 60, no. 10 (October 1, 1987): 766–70.

PMID
3661390
Scholars@Duke

Topol, E. J., R. M. Califf, B. S. George, D. J. Kereiakes, C. W. Abbottsmith, R. J. Candela, K. L. Lee, B. Pitt, R. S. Stack, and W. W. O’Neill. “A randomized trial of immediate versus delayed elective angioplasty after intravenous tissue plasminogen activator in acute myocardial infarction..” N Engl J Med 317, no. 10 (September 3, 1987): 581–88. https://doi.org/10.1056/NEJM198709033171001.

PMID
2956516
Full Text

Mark, D. B., M. A. Hlatky, F. E. Harrell, K. L. Lee, R. M. Califf, and D. B. Pryor. “Exercise treadmill score for predicting prognosis in coronary artery disease..” Ann Intern Med 106, no. 6 (June 1987): 793–800.

PMID
3579066
Scholars@Duke

Hlatky, M. A., D. B. Mark, F. E. Harrell, K. L. Lee, R. M. Califf, and D. B. Pryor. “Rethinking sensitivity and specificity..” Am J Cardiol 59, no. 12 (May 1, 1987): 1195–98.

PMID
3554956
Scholars@Duke

Utz, J. A., R. J. Herfkens, J. A. Heinsimer, T. Bashore, R. Califf, G. Glover, N. Pelc, and A. Shimakawa. “Cine MR determination of left ventricular ejection fraction..” Ajr Am J Roentgenol 148, no. 5 (May 1987): 839–43. https://doi.org/10.2214/ajr.148.5.839.

PMID
3495115
Full Text

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