Robert M. Califf

Professor of Medicine
Donald F. Fortin, M.D. Professor of Cardiology, in the School of Medicine
Member of the Duke Clinical Research Institute
Campus mail 100 Trent Drive, Suite401, Davison Building, Durham, NC 27710
Phone (919) 668-9222
Email address robert.califf@duke.edu

Robert Califf, MD MACC, is the Donald F. Fortin, MD, Professor of Cardiology. He is also Professor of Medicine in the Division of Cardiology and remains a practicing cardiologist. Dr. Califf was the Commissioner of Food and Drugs in 2016-2017 and  Deputy Commissioner for Medical Products and Tobacco from February 2015 until his appointment as Commissioner in February 2016. Prior to joining the FDA, Dr. Califf was a professor of medicine and vice chancellor for clinical and translational research at Duke University. He also served as director of the Duke Translational Medicine Institute and founding director of the Duke Clinical Research Institute. A nationally and internationally recognized expert in cardiovascular medicine, health outcomes research, healthcare quality, and clinical research, Dr. Califf has led many landmark clinical trials and is one of the most frequently cited authors in biomedical science, with more than 1,200 publications in the peer-reviewed literature.

Dr. Califf is a Member of the National Academy of Medicine (formerly known as the Institute of Medicine (IOM)) in 2016, one of the highest honors in the fields of health and medicine. Dr. Califf has served on numerous IOM committees, and he has served as a member of the FDA Cardiorenal Advisory Panel and FDA Science Board's Subcommittee on Science and Technology. Dr. Califf has also served on the Board of Scientific Counselors for the National Library of Medicine, as well as on advisory committees for the National Cancer Institute, the National Heart, Lung, and Blood Institute, the National Institute of Environmental Health Sciences and the Council of the National Institute on Aging.

He has led major initiatives aimed at improving methods and infrastructure for clinical research, including the Clinical Trials Transformation Initiative (CTTI), a public-private partnership co-founded by the FDA and Duke. He also served as the principal investigator for Duke's Clinical and Translational Science Award and the NIH Health Care Systems Research Collaboratory coordinating center and co-PI of the Patient Centered Outcomes Research Institute Network.

Associated Faculty Labs

Publications

Califf, RM, Lee, KL, Harrell, FE, Kimm, SY, Grufferman, S, and Rosati, RA. "Assessment of the use of the age- and sex-specific United States population as a control group for analysis of survival in coronary artery disease." The American Journal of Cardiology 50, no. 6 (December 1982): 1279-1282.

PMID
7148703
Full Text

Wagner, GS, Califf, RM, Pryor, D, and Rosati, RA. "Early hospital discharge after uncomplicated acute myocardial infarction." Delaware Medical Journal 54, no. 10 (October 1982): 565-572.

PMID
7173458
Scholars@Duke

Califf, RM, McKinnis, RA, Burks, J, Lee, KL, Harrell, FE, Behar, VS, Pryor, DB, Wagner, GS, and Rosati, RA. "Prognostic implications of ventricular arrhythmias during 24 hour ambulatory monitoring in patients undergoing cardiac catheterization for coronary artery disease." The American Journal of Cardiology 50, no. 1 (July 1982): 23-31.

PMID
6124117
Full Text

Rosati, RA, Lee, KL, Califf, RM, Pryor, DB, and Harrell, FE. "Problems and advantages of an observational data base approach to evaluating the effect of therapy on outcome." Circulation 65, no. 7 Pt 2 (June 1982): 27-32.

PMID
7044604
Full Text

Harrell, FE, Califf, RM, Pryor, DB, Lee, KL, and Rosati, RA. "Evaluating the yield of medical tests." Jama 247, no. 18 (May 1982): 2543-2546.

PMID
7069920
Full Text

Williams, RS, Wallace, AG, Hindman, MC, Califf, RM, Blumenthal, JA, Paul Koisch, F, Morey, MC, Wagner, ED, Mau, HS, Williams, JS, Rhoads, MK, Erickson, P, Leckie, DJ, and James, JM. "Duke university’s preventive approach to cardiology-DUPAC." Journal of Cardiac Rehabilitation 2, no. 6 (January 1, 1982): 509-514.

Scholars@Duke

Rosati, RA, Lee, KL, and Califf, RM. "Problem and advantages of an observational data base approach to evaluating the effect of therapy on outcome." Circulation 65, no. 7 II (1982): II-27-II-32-null.

Scholars@Duke

Califf, RM, and Rosati, RA. "The doctor and the computer." The Western Journal of Medicine 135, no. 4 (October 1981): 321-323.

PMID
7342460
Scholars@Duke

Califf, RM, Burks, JM, Behar, VS, Margolis, JR, and Wagner, GS. "Relationships among ventricular arrhythmias, coronary artery disease, and angiographic and electrocardiographic indicators of myocardial fibrosis." Circulation 57, no. 4 (April 1978): 725-732.

PMID
75774
Full Text

"Platelet Glycoprotein IIb/IIIa Receptor Blockade after Coronary Angioplasty." New England Journal of Medicine 337, no. 17 (October 23, 1997): 1243-1245.

Full Text

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