Sana Mustapha Al-Khatib, MD

Professor of Medicine
Member in the Duke Clinical Research Institute
Campus mail 7521 N Pavilion Bldg, Durham, NC 27715
Phone (919) 668-8649
Email address alkha001@duke.edu

Dr. Sana M. Al-Khatib is a tenured Professor of Medicine at Duke University Medical Center, a board-certified clinical electrophysiologist and an experienced clinical researcher in cardiac arrhythmias.  As a graduate of the NIH-funded Clinical Research Training Program, she is one of a few electrophysiologists nationwide with expertise in quantitative research methods. Her clinical expertise is in sudden cardiac death prevention, atrial fibrillation and ventricular arrhythmias, and implantable cardiac devices. Her research expertise lies in the design and conduct of clinical trials, outcomes research, and cost-effectiveness analyses. She is a recipient of a National Heart, Lung and Blood Institute’s R-01 grant titled “Implantable Cardioverter Defibrillator Therapy in Patients with Heart Failure” (2009-2013) and of an American Heart Association Career Development Award (2002-2006). She is a Co-Principal Investigator on an NHLBI-funded T-32 Postdoctoral Training in Cardiovascular Clinical Research and on several Agency of Healthcare Research and Quality sponsored R-01 grants including the “Duke Cardiovascular Center for Education and Research on Therapeutics.” She has more than 130 publications in peer-reviewed journals. She has established several collaborative research efforts both within and outside her institution. The goals of these collaborations are to synergize efforts aimed at improving the survival and quality of life of patients at risk for sudden cardiac death and those with atrial and ventricular arrhythmias through clinical trials and outcomes-based research and to evaluate study design and data analysis in order to improve the quality of research done in these arenas. Dr. Al-Khatib is an Associate Editor for the American Heart Journal and is on the Editorial Board for the Journal of Cardiovascular Electrophysiology. Dr. Al-Khatib serves on multiple national committees including the Heart Rhythm Society Board of Trustees, the Heart Rhythm Society Health Policy committee, the Heart Rhythm Society Legislative subcommittee, the Heart Rhythm Society Program Planning committee, the American College of Cardiology ICD Registry Steering committee, and the National Quality Forum Cardiovascular Steering committee.

In Their Words

Education and Training

  • Fellow in Cardiology, Medicine, Duke University, 1996 - 2000
  • Medical Resident, Medicine, Duke University, 1993 - 1996
  • M.D., American University of Beirut (Lebanon), 1993

Publications

Assimon, Magdalene M., Patrick H. Pun, Lily Chin-Hua Wang, Sana M. Al-Khatib, M Alan Brookhart, David J. Weber, Wolfgang C. Winkelmayer, and Jennifer E. Flythe. “Analysis of Respiratory Fluoroquinolones and the Risk of Sudden Cardiac Death Among Patients Receiving Hemodialysis.” Jama Cardiol 7, no. 1 (January 1, 2022): 75–83. https://doi.org/10.1001/jamacardio.2021.4234.

PMID
34668928
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Tamirisa, Kamala P., Sana M. Al-Khatib, Sanghamitra Mohanty, Janet K. Han, Andrea Natale, Dhiraj Gupta, Andrea M. Russo, Amin Al-Ahmad, Anne M. Gillis, and Kevin L. Thomas. “Racial and Ethnic Differences in the Management of Atrial Fibrillation.” Cjc Open 3, no. 12 Suppl (December 2021): S137–48. https://doi.org/10.1016/j.cjco.2021.09.004.

PMID
34993443
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Mastoris, Ioannis, Harriette GC Van Spall, Seth H. Sheldon, Rhea C. Pimentel, Leslie Steinkamp, Zubair Shah, Sana M. Al-Khatib, Jagmeet P. Singh, and Andrew J. Sauer. “Emerging Implantable-Device Technology for Patients at the Intersection of Electrophysiology and Heart Failure Interdisciplinary Care.” J Card Fail, November 10, 2021. https://doi.org/10.1016/j.cardfail.2021.11.006.

PMID
34774748
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Darden, Douglas, Thao Duong, Chengan Du, Muhammad Bilal Munir, Frederick T. Han, Ryan Reeves, Jacqueline Saw, et al. “Sex Differences in Procedural Outcomes Among Patients Undergoing Left Atrial Appendage Occlusion: Insights From the NCDR LAAO Registry.” Jama Cardiol 6, no. 11 (November 1, 2021): 1275–84. https://doi.org/10.1001/jamacardio.2021.3021.

PMID
34379072
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Starks, Monique Anderson, Larry R. Jackson, Anne Hellkamp, Sana M. Al-Khatib, Daniel B. Mark, Kevin L. Thomas, Graham Nichol, et al. “Outcomes for patients with anterior myocardial infarction and prior cardiac arrest in the home automated external defibrillator trial (HAT).” Resuscitation 168 (November 2021): 75–83. https://doi.org/10.1016/j.resuscitation.2021.08.047.

PMID
34500022
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Arps, Kelly, Jonathan P. Piccini, Rebecca Yapejian, Rhonda Leguire, Brenda Smith, Sana M. Al-Khatib, Tristram D. Bahnson, et al. “Optimizing mechanically sensed atrial tracking in patients with atrioventricular-synchronous leadless pacemakers: A single-center experience.” Heart Rhythm O2 2, no. 5 (October 2021): 455–62. https://doi.org/10.1016/j.hroo.2021.08.003.

PMID
34667960
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Benjamin, Emelia J., Sana M. Al-Khatib, Patrice Desvigne-Nickens, Alvaro Alonso, Luc Djoussé, Daniel E. Forman, Anne M. Gillis, et al. “Research Priorities in the Secondary Prevention of Atrial Fibrillation: A National Heart, Lung, and Blood Institute Virtual Workshop Report.” J Am Heart Assoc 10, no. 16 (August 17, 2021): e021566. https://doi.org/10.1161/JAHA.121.021566.

PMID
34351783
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Writing Committee Members, Y Joseph, Catherine M. Otto, Rick A. Nishimura, Robert O. Bonow, Blase A. Carabello, John P. Erwin, Federico Gentile, et al. “2020 ACC/AHA guideline for the management of patients with valvular heart disease: A report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.” J Thorac Cardiovasc Surg 162, no. 2 (August 2021): e183–353. https://doi.org/10.1016/j.jtcvs.2021.04.002.

PMID
33972115
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Writing Committee Members, Y Joseph, Steve R. Ommen, Seema Mital, Michael A. Burke, Sharlene M. Day, Anita Deswal, Perry Elliott, et al. “2020 AHA/ACC guideline for the diagnosis and treatment of patients with hypertrophic cardiomyopathy: A report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.” J Thorac Cardiovasc Surg 162, no. 1 (July 2021): e23–106. https://doi.org/10.1016/j.jtcvs.2021.04.001.

PMID
33926766
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