Sana Mustapha Al-Khatib, MD

Professor of Medicine
Member in the Duke Clinical Research Institute
Campus mail 7521 N Pavilion Bldg, Durham, NC 27715
Phone (919) 668-8649
Email address alkha001@mc.duke.edu

Dr. Sana M. Al-Khatib is a tenured Professor of Medicine at Duke University Medical Center, a board-certified clinical electrophysiologist and an experienced clinical researcher in cardiac arrhythmias.  As a graduate of the NIH-funded Clinical Research Training Program, she is one of a few electrophysiologists nationwide with expertise in quantitative research methods. Her clinical expertise is in sudden cardiac death prevention, atrial fibrillation and ventricular arrhythmias, and implantable cardiac devices. Her research expertise lies in the design and conduct of clinical trials, outcomes research, and cost-effectiveness analyses. She is a recipient of a National Heart, Lung and Blood Institute’s R-01 grant titled “Implantable Cardioverter Defibrillator Therapy in Patients with Heart Failure” (2009-2013) and of an American Heart Association Career Development Award (2002-2006). She is a Co-Principal Investigator on an NHLBI-funded T-32 Postdoctoral Training in Cardiovascular Clinical Research and on several Agency of Healthcare Research and Quality sponsored R-01 grants including the “Duke Cardiovascular Center for Education and Research on Therapeutics.” She has more than 130 publications in peer-reviewed journals. She has established several collaborative research efforts both within and outside her institution. The goals of these collaborations are to synergize efforts aimed at improving the survival and quality of life of patients at risk for sudden cardiac death and those with atrial and ventricular arrhythmias through clinical trials and outcomes-based research and to evaluate study design and data analysis in order to improve the quality of research done in these arenas. Dr. Al-Khatib is an Associate Editor for the American Heart Journal and is on the Editorial Board for the Journal of Cardiovascular Electrophysiology. Dr. Al-Khatib serves on multiple national committees including the Heart Rhythm Society Board of Trustees, the Heart Rhythm Society Health Policy committee, the Heart Rhythm Society Legislative subcommittee, the Heart Rhythm Society Program Planning committee, the American College of Cardiology ICD Registry Steering committee, and the National Quality Forum Cardiovascular Steering committee.

In Their Words

Education and Training

  • Fellow in Cardiology, Medicine, Duke University, 1996 - 2000
  • Medical Resident, Medicine, Duke University, 1993 - 1996
  • M.D., American University of Beirut (Lebannon), 1993

Publications

Friedman, DJ, Parzynski, CS, Heist, EK, Russo, AM, Akar, JG, Freeman, JV, Curtis, JP, and Al-Khatib, SM. "Ventricular Fibrillation Conversion Testing After Implantation of a Subcutaneous Implantable Cardioverter Defibrillator: A Report from the National Cardiovascular Data Registry." Circulation (February 20, 2018).

PMID
29463509
Full Text

Crowley, MJ, Al-Khatib, SM, Wang, TY, Khazanie, P, Kressin, NR, Krumholz, HM, Kiefe, CI, Wells, BL, O'Brien, SM, Peterson, ED, and Sanders, GD. "How well does early-career investigators' cardiovascular outcomes research training align with funded outcomes research?." American Heart Journal 196 (February 2018): 163-169.

PMID
29421009
Full Text

Khazanie, P, Al-Khatib, SM, Wang, TY, Crowley, MJ, Kressin, NR, Krumholz, HM, Kiefe, CI, Wells, BL, O'Brien, SM, Peterson, ED, and Sanders, GD. "Training cardiovascular outcomes researchers: A survey of mentees and mentors to identify critical training gaps and needs." American Heart Journal 196 (February 2018): 170-177.

PMID
29421010
Full Text

Friedman, DJ, Black-Maier, EW, Barnett, AS, Pokorney, SD, Al-Khatib, SM, Jackson, KP, Bahnson, TD, Ellis, CR, Atwater, BD, Lewis, RK, and Piccini, JP. "Left Atrial Appendage Electrical Isolation for Treatment of Recurrent Atrial Fibrillation: A Meta-Analysis." Jacc. Clinical Electrophysiology 4, no. 1 (January 2018): 112-120.

PMID
29600775
Full Text

Al-Khatib, SM, Gillis, AM, and Curtis, AB. "Centers for Medicare and Medicaid Services' Decision to Reconsider Coverage Indications for ICDs: Where to Now?." Circulation 137, no. 4 (January 2018): 317-319.

PMID
29070501
Full Text

Black-Maier, E, Ren, X, Steinberg, BA, Green, CL, Barnett, AS, Rosa, NS, Al-Khatib, SM, Atwater, BD, Daubert, JP, Frazier-Mills, C, Grant, AO, Hegland, DD, Jackson, KP, Jackson, LR, Koontz, JI, Lewis, RK, Sun, AY, Thomas, KL, Bahnson, TD, and Piccini, JP. "Catheter ablation of atrial fibrillation in patients with heart failure and preserved ejection fraction." Heart rhythm (December 5, 2017).

PMID
29222043
Full Text

Sharma, A, Green, JB, Dunning, A, Lokhnygina, Y, Al-Khatib, SM, Lopes, RD, Buse, JB, Lachin, JM, Van de Werf, F, Armstrong, PW, Kaufman, KD, Standl, E, Chan, JCN, Distiller, LA, Scott, R, Peterson, ED, Holman, RR, and TECOS Study Group, . "Causes of Death in a Contemporary Cohort of Patients With Type 2 Diabetes and Atherosclerotic Cardiovascular Disease: Insights From the TECOS Trial." Diabetes Care 40, no. 12 (December 2017): 1763-1770.

PMID
28986504
Full Text

Pokorney, SD, and Al-Khatib, SM. "Implantable Cardioverter-Defibrillators in Patients With Left Ventricular Assist Devices: On Trial and in Need of a Trial." JACC. Heart failure 5, no. 12 (December 2017): 927-929.

PMID
29191300
Full Text

Zeitler, EP, Al-Khatib, SM, Friedman, DJ, Han, JY, Poole, JE, Bardy, GH, Bigger, JT, Buxton, AE, Moss, AJ, Lee, KL, Dorian, P, Cappato, R, Kadish, AH, Kudenchuk, PJ, Mark, DB, Inoue, LYT, and Sanders, GD. "Predicting appropriate shocks in patients with heart failure: Patient level meta-analysis from SCD-HeFT and MADIT II." November 2017.

PMID
28744959
Full Text

Al-Khatib, SM, Fonarow, GC, and Sanders, GD. "Implantable Cardioverter Defibrillators for Nonischemic Cardiomyopathy-Reply." JAMA cardiology 2, no. 11 (November 2017): 1283-1284.

PMID
28975189
Full Text

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