Sana Mustapha Al-Khatib, MD

Professor of Medicine
Member in the Duke Clinical Research Institute
Campus mail 7521 N Pavilion Bldg, Durham, NC 27715
Phone (919) 668-8649
Email address alkha001@duke.edu

Dr. Sana M. Al-Khatib is a tenured Professor of Medicine at Duke University Medical Center, a board-certified clinical electrophysiologist and an experienced clinical researcher in cardiac arrhythmias.  As a graduate of the NIH-funded Clinical Research Training Program, she is one of a few electrophysiologists nationwide with expertise in quantitative research methods. Her clinical expertise is in sudden cardiac death prevention, atrial fibrillation and ventricular arrhythmias, and implantable cardiac devices. Her research expertise lies in the design and conduct of clinical trials, outcomes research, and cost-effectiveness analyses. She is a recipient of a National Heart, Lung and Blood Institute’s R-01 grant titled “Implantable Cardioverter Defibrillator Therapy in Patients with Heart Failure” (2009-2013) and of an American Heart Association Career Development Award (2002-2006). She is a Co-Principal Investigator on an NHLBI-funded T-32 Postdoctoral Training in Cardiovascular Clinical Research and on several Agency of Healthcare Research and Quality sponsored R-01 grants including the “Duke Cardiovascular Center for Education and Research on Therapeutics.” She has more than 130 publications in peer-reviewed journals. She has established several collaborative research efforts both within and outside her institution. The goals of these collaborations are to synergize efforts aimed at improving the survival and quality of life of patients at risk for sudden cardiac death and those with atrial and ventricular arrhythmias through clinical trials and outcomes-based research and to evaluate study design and data analysis in order to improve the quality of research done in these arenas. Dr. Al-Khatib is an Associate Editor for the American Heart Journal and is on the Editorial Board for the Journal of Cardiovascular Electrophysiology. Dr. Al-Khatib serves on multiple national committees including the Heart Rhythm Society Board of Trustees, the Heart Rhythm Society Health Policy committee, the Heart Rhythm Society Legislative subcommittee, the Heart Rhythm Society Program Planning committee, the American College of Cardiology ICD Registry Steering committee, and the National Quality Forum Cardiovascular Steering committee.

In Their Words

Education and Training

  • Fellow in Cardiology, Medicine, Duke University, 1996 - 2000
  • Medical Resident, Medicine, Duke University, 1993 - 1996
  • M.D., American University of Beirut (Lebanon), 1993

Publications

Atwater, Brett D., Vivian P. Thompson, Richard N. Vest, Linda K. Shaw, Walter R. Mazzei, Sana M. Al-Khatib, Patrick M. Hranitzky, et al. “75% narrowing) coronary artery disease.” Am J Cardiol 104, no. 12 (December 15, 2009): 1624–30. https://doi.org/10.1016/j.amjcard.2009.07.042.

PMID
19962465
Full Text

Piccini, Jonathan P., Renato D. Lopes, Melissa H. Kong, Vic Hasselblad, Kevin Jackson, and Sana M. Al-Khatib. “Pulmonary vein isolation for the maintenance of sinus rhythm in patients with atrial fibrillation: a meta-analysis of randomized, controlled trials.” Circ Arrhythm Electrophysiol 2, no. 6 (December 2009): 626–33. https://doi.org/10.1161/CIRCEP.109.856633.

PMID
20009077
Full Text

Piccini, Jonathan P., Aijing Z. Starr, John R. Horton, Linda K. Shaw, Kerry L. Lee, Sana M. Al-Khatib, Ami E. Iskandrian, Christopher M. O’Connor, and Salvador Borges-Neto. “ 35%.” In Circulation, 120:S319–S319. LIPPINCOTT WILLIAMS & WILKINS, 2009.

Scholars@Duke

Al-Khatib, Sana M., Gail Hafley, Robert A. Harrington, Michael J. Mack, Thomas Bruce Ferguson, Eric D. Peterson, Robert M. Califf, Nicholas T. Kouchoukos, and John H. Alexander. “Patterns of management of atrial fibrillation complicating coronary artery bypass grafting: Results from the PRoject of Ex-vivo Vein graft ENgineering via Transfection IV (PREVENT-IV) Trial.” Am Heart J 158, no. 5 (November 2009): 792–98. https://doi.org/10.1016/j.ahj.2009.09.003.

PMID
19853700
Full Text

Pun, Patrick H., Thomas R. Smarz, Emily F. Honeycutt, Linda K. Shaw, Sana M. Al-Khatib, and John P. Middleton. “Chronic kidney disease is associated with increased risk of sudden cardiac death among patients with coronary artery disease.” Kidney Int 76, no. 6 (September 2009): 652–58. https://doi.org/10.1038/ki.2009.219.

PMID
19536082
Full Text

LaPointe, Nancy M Allen, Judith A. Stafford, Paul A. Pappas, Sana M. Al-Khatib, and Kevin J. Anstrom. “Use of beta-blockers in patients with an implantable cardioverter defibrillator.” Ann Pharmacother 43, no. 7 (July 2009): 1189–96. https://doi.org/10.1345/aph.1M140.

PMID
19567655
Full Text

Majidi, Mohamed, Andrzej S. Kosinski, Sana M. Al-Khatib, Miguel E. Lemmert, Lilian Smolders, Anton van Weert, Johan H. C. Reiber, et al. “Reperfusion ventricular arrhythmia 'bursts' predict larger infarct size despite TIMI 3 flow restoration with primary angioplasty for anterior ST-elevation myocardial infarction.” Eur Heart J 30, no. 7 (April 2009): 757–64. https://doi.org/10.1093/eurheartj/ehp005.

PMID
19202155
Full Text

Kong, Melissa H., Renato D. Lopes, Jonathan P. Piccini, Vic Hasselblad, Tristram D. Bahnson, and Sana M. Al-Khatib. “Surgical Maze Procedure as a Treatment for Atrial Fibrillation: A Meta-Analysis of Randomized Controlled Trials.” Journal of the American College of Cardiology 53, no. 10 (March 10, 2009): A118–A118.

Scholars@Duke

Lopes, Renato D., Aijing Starr, Sana M. Al-Khatib, L Kristin Newby, Rajendra H. Mehta, Frans Van de Werf, Kenneth W. Mahaffey, et al. “Warfarin Is Independently Associated With Lower Risk of Six-Month Death or Myocardial Infarction in Patients With Atrial Fibrillation Following Acute Coronary Syndromes.” Journal of the American College of Cardiology 53, no. 10 (March 10, 2009): A354–A354.

Scholars@Duke

Shah, Bimal, Adrian F. Hernandez, Li Liang, Sana M. Al-Khatib, Clyde W. Yancy, Gregg C. Fonarow, Eric D. Peterson, and Eric D. Get With The Guidelines Steering Committee. “Hospital variation and characteristics of implantable cardioverter-defibrillator use in patients with heart failure: data from the GWTG-HF (Get With The Guidelines-Heart Failure) registry.” J Am Coll Cardiol 53, no. 5 (February 3, 2009): 416–22. https://doi.org/10.1016/j.jacc.2008.09.045.

PMID
19179199
Full Text

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