Sana Mustapha Al-Khatib, MD

Professor of Medicine
Member in the Duke Clinical Research Institute
Campus mail 7521 N Pavilion Bldg, Durham, NC 27715
Phone (919) 668-8649
Email address alkha001@mc.duke.edu

Dr. Sana M. Al-Khatib is a tenured Professor of Medicine at Duke University Medical Center, a board-certified clinical electrophysiologist and an experienced clinical researcher in cardiac arrhythmias.  As a graduate of the NIH-funded Clinical Research Training Program, she is one of a few electrophysiologists nationwide with expertise in quantitative research methods. Her clinical expertise is in sudden cardiac death prevention, atrial fibrillation and ventricular arrhythmias, and implantable cardiac devices. Her research expertise lies in the design and conduct of clinical trials, outcomes research, and cost-effectiveness analyses. She is a recipient of a National Heart, Lung and Blood Institute’s R-01 grant titled “Implantable Cardioverter Defibrillator Therapy in Patients with Heart Failure” (2009-2013) and of an American Heart Association Career Development Award (2002-2006). She is a Co-Principal Investigator on an NHLBI-funded T-32 Postdoctoral Training in Cardiovascular Clinical Research and on several Agency of Healthcare Research and Quality sponsored R-01 grants including the “Duke Cardiovascular Center for Education and Research on Therapeutics.” She has more than 130 publications in peer-reviewed journals. She has established several collaborative research efforts both within and outside her institution. The goals of these collaborations are to synergize efforts aimed at improving the survival and quality of life of patients at risk for sudden cardiac death and those with atrial and ventricular arrhythmias through clinical trials and outcomes-based research and to evaluate study design and data analysis in order to improve the quality of research done in these arenas. Dr. Al-Khatib is an Associate Editor for the American Heart Journal and is on the Editorial Board for the Journal of Cardiovascular Electrophysiology. Dr. Al-Khatib serves on multiple national committees including the Heart Rhythm Society Board of Trustees, the Heart Rhythm Society Health Policy committee, the Heart Rhythm Society Legislative subcommittee, the Heart Rhythm Society Program Planning committee, the American College of Cardiology ICD Registry Steering committee, and the National Quality Forum Cardiovascular Steering committee.

In Their Words

Education and Training

  • Fellow in Cardiology, Medicine, Duke University, 1996 - 2000
  • Medical Resident, Medicine, Duke University, 1993 - 1996
  • M.D., American University of Beirut (Lebannon), 1993

Publications

Randolph, TC, Hellkamp, AS, Zeitler, EP, Fonarow, GC, Hernandez, AF, Thomas, KL, Peterson, ED, Yancy, CW, and Al-Khatib, SM. "Utilization of cardiac resynchronization therapy in eligible patients hospitalized for heart failure and its association with patient outcomes." July 2017.

PMID
28625381
Full Text

Randolph, TC, Hellkamp, AS, Zeitler, EP, Fonarow, GC, Hernandez, AF, Thomas, KL, Peterson, ED, Yancy, CW, and Al-Khatib, SM. "Utilization of cardiac resynchronization therapy in eligible patients hospitalized for heart failure and its association with patient outcomes." American Heart Journal 189 (July 2017): 48-58.

Full Text

Nishimura, RA, Otto, CM, Bonow, RO, Carabello, BA, Erwin, JP, Fleisher, LA, Jneid, H, Mack, MJ, McLeod, CJ, O’Gara, PT, Rigolin, VH, Sundt, TM, and Thompson, A. "2017 AHA/ACC Focused Update of the 2014 AHA/ACC Guideline for the Management of Patients With Valvular Heart Disease." Journal of the American College of Cardiology 70, no. 2 (July 2017): 252-289.

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Lopes, RD, Guimarães, PO, Kolls, BJ, Wojdyla, DM, Bushnell, CD, Hanna, M, Easton, JD, Thomas, L, Wallentin, L, Al-Khatib, SM, Held, C, Gabriel Melo de Barros E Silva, P, Alexander, JH, Granger, CB, and Diener, H-C. "Intracranial hemorrhage in patients with atrial fibrillation receiving anticoagulation therapy." Blood 129, no. 22 (June 2017): 2980-2987.

PMID
28356246
Full Text

Al-Khatib, SM, Fonarow, GC, Joglar, JA, Inoue, LYT, Mark, DB, Lee, KL, Kadish, A, Bardy, G, and Sanders, GD. "Primary Prevention Implantable Cardioverter Defibrillators in Patients With Nonischemic Cardiomyopathy: A Meta-analysis." Jama Cardiology 2, no. 6 (June 2017): 685-688.

PMID
28355432
Full Text

Pokorney, SD, Parzynski, CS, Daubert, JP, Hegland, DD, Varosy, PD, Curtis, JP, and Al-Khatib, SM. "Temporal Trends in and Factors Associated With Use of Single- Versus Dual-Coil Implantable Cardioverter-Defibrillator Leads." JACC: Clinical Electrophysiology 3, no. 6 (June 2017): 612-619.

Full Text

Cowper, PA, Sheng, S, Lopes, RD, Anstrom, KJ, Stafford, JA, Davidson-Ray, L, Al-Khatib, SM, Ansell, J, Dorian, P, Husted, S, McMurray, JJV, Steg, PG, Alexander, JH, Wallentin, L, Granger, CB, and Mark, DB. "Economic Analysis of Apixaban Therapy for Patients With Atrial Fibrillation From a US Perspective: Results From the ARISTOTLE Randomized Clinical Trial." Jama Cardiology 2, no. 5 (May 2017): 525-534.

PMID
28355434
Full Text

Pokorney, SD, Mi, X, Hammill, BG, Allen LaPointe, NM, Curtis, LH, and Al-Khatib, SM. "Use of Antiarrhythmic Medications in Medicare Part D Patients With an Implantable Cardioverter-Defibrillator and Ventricular Tachycardia." The American Journal of Cardiology 119, no. 9 (May 2017): 1401-1406.

PMID
28341360
Full Text

Zeitler, EP, Friedman, DJ, Daubert, JP, Al-Khatib, SM, Solomon, SD, Biton, Y, McNitt, S, Zareba, W, Moss, AJ, and Kutyifa, V. "Multiple Comorbidities and Response to Cardiac Resynchronization Therapy: MADIT-CRT Long-Term Follow-Up." Journal of the American College of Cardiology 69, no. 19 (May 2017): 2369-2379.

PMID
28494974
Full Text

Pun, PH, Sheng, S, Sanders, G, DeVore, AD, Friedman, D, Fonarow, GC, Heidenreich, PA, Yancy, CW, Hernandez, AF, and Al-Khatib, SM. "Prescription of Guideline-Recommended Implantable Cardioverter Defibrillator and Cardiac Resynchronization Therapy Among Patients Hospitalized With Heart Failure and Varying Degrees of Renal Function." The American journal of cardiology 119, no. 6 (March 2017): 886-892.

PMID
28160975
Full Text

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