Scott Michael Palmer, MD

Professor of Medicine
Member in the Duke Clinical Research Institute
Vice-Chair for Research in the Department of Medicine
Professor in Immunology
Professor in Population Health Sciences
Core Faculty in Innovation & Entrepreneurship
Campus mail 2085 Msrb2 2 Genome Ct, Durham, NC 27710
Phone (919) 684-0245
Email address scott.palmer@duke.edu

Dr. Palmer leads a successful program of clinical, basic and translational research in transplantation and advanced lung diseases. He currently directs the pulmonary research program at the Duke Clinical Research Institute (DCRI) and serves as Vice Chair for Research in the Department of Medicine.

Dr. Palmer has over 150 peer reviewed publications, received numerous awards, including election into the American Society for Clinical Investigation (ASCI) in 2012, chaired many sessions at national and international meetings, serves regularly on NIH study sections, and is on the editorial board of many prominent journals. He is also Associate Director of the Clinical Research Training Program at Duke and has personally mentored over 40 pre-and post-doctoral trainees, many of whom are now engaged in their own successful research careers.

His scientific accomplishments include the first human studies to demonstrate the importance of innate immunity in transplant rejection and completion of a prospective multicenter study that improved CMV prevention after lung transplantation.

Current basic projects in the lab are studying the role of the matrix in the activation of innate immunity in pulmonary transplant rejection, and epithelial injury and repair in the development of toxin induced bronchiolitis obliterans. Translational and human projects are studying predictors of lung transplant survival in the UNOS database, immune monitoring to predict CMV infection and acute rejection after lung transplantation, and the use of novel inhaled antibiotics in lung transplantation. The lab is also using cutting edge whole exome genetic sequencing to identify genetic predictors of transplant rejection.

Dr. Palmer also leads trials coordinated through the DCRI that study the natural history and investigate new treatments for idiopathic pulmonary fibrosis (IPF), chronic lung transplant rejection, and posttransplant cytomegalovirus infection.

Education and Training

  • Fellow, Pulmonary Medicine, Medicine, Duke University, 1996 - 1999
  • Medical Resident, Medicine, Duke University, 1993 - 1996
  • M.H.S., Duke University, 2000
  • M.D., Duke University, 1993

Publications

Parekh, Priti I., James A. Blumenthal, Michael A. Babyak, Kari Merrill, Robert M. Carney, R Duane Davis, Scott M. Palmer, and Scott M. INSPIRE Investigators. “Psychiatric disorder and quality of life in patients awaiting lung transplantation..” Chest 124, no. 5 (November 2003): 1682–88. https://doi.org/10.1378/chest.124.5.1682.

PMID
14605035
Full Text

Reams, B Diane, H Page McAdams, David N. Howell, Mark P. Steele, R Duane Davis, and Scott M. Palmer. “Posttransplant lymphoproliferative disorder: incidence, presentation, and response to treatment in lung transplant recipients..” Chest 124, no. 4 (October 2003): 1242–49. https://doi.org/10.1378/chest.124.4.1242.

PMID
14555552
Full Text

Palmer, Scott M., Lauranell H. Burch, R Duane Davis, Walter F. Herczyk, David N. Howell, Nancy L. Reinsmoen, and David A. Schwartz. “The role of innate immunity in acute allograft rejection after lung transplantation..” Am J Respir Crit Care Med 168, no. 6 (September 15, 2003): 628–32. https://doi.org/10.1164/rccm.200303-447OC.

PMID
12773319
Full Text

Hadjiliadis, Denis, R. Duane Davis, Mark P. Steele, Robert H. Messier, Christine L. Lau, Steve S. Eubanks, and Scott M. Palmer. “Gastroesophageal reflux disease in lung transplant recipients..” Clin Transplant 17, no. 4 (August 2003): 363–68.

PMID
12868994
Scholars@Duke

Marom, Edith M., Scott M. Palmer, Jeremy J. Erasmus, James E. Herndon, Chunfeng Zhang, and H Page McAdams. “Pleural effusions in lung transplant recipients: image-guided small-bore catheter drainage..” Radiology 228, no. 1 (July 2003): 241–45. https://doi.org/10.1148/radiol.2281020847.

PMID
12832585
Full Text

Mariencheck, William I., John F. Alcorn, Scott M. Palmer, and Jo Rae Wright. “Pseudomonas aeruginosa elastase degrades surfactant proteins A and D..” Am J Respir Cell Mol Biol 28, no. 4 (April 2003): 528–37. https://doi.org/10.1165/rcmb.2002-0141OC.

PMID
12654643
Full Text

Choi, Yo Won, Santiago E. Rossi, Scott M. Palmer, David DeLong, Jeremy J. Erasmus, and H Page McAdams. “Bronchiolitis obliterans syndrome in lung transplant recipients: correlation of computed tomography findings with bronchiolitis obliterans syndrome stage..” J Thorac Imaging 18, no. 2 (April 2003): 72–79.

PMID
12700480
Scholars@Duke

Davis, R Duane, Christine L. Lau, Steve Eubanks, Robert H. Messier, Denis Hadjiliadis, Mark P. Steele, and Scott M. Palmer. “Improved lung allograft function after fundoplication in patients with gastroesophageal reflux disease undergoing lung transplantation..” J Thorac Cardiovasc Surg 125, no. 3 (March 2003): 533–42. https://doi.org/10.1067/mtc.2003.166.

PMID
12658195
Full Text

Patel, Vijay S., Scott M. Palmer, Robert H. Messier, and R Duane Davis. “Clinical outcome after coronary artery revascularization and lung transplantation..” Ann Thorac Surg 75, no. 2 (February 2003): 372–77. https://doi.org/10.1016/s0003-4975(02)04639-8.

PMID
12607642
Full Text

Palmer, S. M., S. Garantziotis, and N. L. Reinsmoen. “Clinical significance of anti human leukocyte antigen antibodies in lung transplantation.” Current Opinion in Organ Transplantation 8, no. 3 (January 1, 2003): 217–21. https://doi.org/10.1097/00075200-200309000-00001.

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