Scott Michael Palmer, MD

Professor of Medicine
Member in the Duke Clinical Research Institute
Vice-Chair for Research in the Department of Medicine
Professor in Immunology
Core Faculty in Innovation & Entrepreneurship
Campus mail 2085 Msrb2 2 Genome Ct, Durham, NC 27710
Phone (919) 684-0245
Email address

Dr. Palmer leads a successful program of clinical, basic and translational research in transplantation and advanced lung diseases. He currently directs the pulmonary research program at the Duke Clinical Research Institute (DCRI) and serves as Vice Chair for Research in the Department of Medicine.

Dr. Palmer has over 150 peer reviewed publications, received numerous awards, including election into the American Society for Clinical Investigation (ASCI) in 2012, chaired many sessions at national and international meetings, serves regularly on NIH study sections, and is on the editorial board of many prominent journals. He is also Associate Director of the Clinical Research Training Program at Duke and has personally mentored over 40 pre-and post-doctoral trainees, many of whom are now engaged in their own successful research careers.

His scientific accomplishments include the first human studies to demonstrate the importance of innate immunity in transplant rejection and completion of a prospective multicenter study that improved CMV prevention after lung transplantation.

Current basic projects in the lab are studying the role of the matrix in the activation of innate immunity in pulmonary transplant rejection, and epithelial injury and repair in the development of toxin induced bronchiolitis obliterans. Translational and human projects are studying predictors of lung transplant survival in the UNOS database, immune monitoring to predict CMV infection and acute rejection after lung transplantation, and the use of novel inhaled antibiotics in lung transplantation. The lab is also using cutting edge whole exome genetic sequencing to identify genetic predictors of transplant rejection.

Dr. Palmer also leads trials coordinated through the DCRI that study the natural history and investigate new treatments for idiopathic pulmonary fibrosis (IPF), chronic lung transplant rejection, and posttransplant cytomegalovirus infection.

Education and Training

  • Fellow, Pulmonary Medicine, Medicine, Duke University, 1996 - 1999
  • Medical Resident, Medicine, Duke University, 1993 - 1996
  • M.H.S., Duke University, 2000
  • M.D., Duke University, 1993


Palmer, SM, and Tapson, VF. "Pulmonary rehabilitation in the surgical patient. Lung transplantation and lung volume reduction surgery." Respir Care Clin N Am 4, no. 1 (March 1998): 71-83. (Review)


Palmer, SM, Layish, DT, Kussin, PS, Oury, T, Davis, RD, and Tapson, VF. "Lung transplantation for Williams-Campbell syndrome." Chest 113, no. 2 (February 1998): 534-537.


Mariencheck, WI, Tapson, VF, and Palmer, SM. "Alterations of pulmonary Surfactant Protein A (SP-A) in bronchoalveolar lavage of human lung transplant recipients." Chest 114, no. 4 SUPPL. (1998): 397S-.


McAdams, HP, and Palmer, SM. "Acute, life threatening complications of lung transplantation - Invited commentary." RADIOGRAPHICS 18, no. 1 (1998): 43-46.


Palmer, SM, Robinson, LJ, Wang, A, Gossage, JR, Bashore, T, and Tapson, VF. "Massive pulmonary edema and death after prostacyclin infusion in a patient with pulmonary veno-occlusive disease." Chest 113, no. 1 (January 1998): 237-240.


Liu, K, Palmer, SM, Vollmer, RT, Dodd, LG, Henshaw, NG, Harrell, LJ, Tapson, VF, and Howell, DN. "Comparison of microbiologic, histologic and cytologic studies for the identification of cytomegalovirus in lung transplant patients." MODERN PATHOLOGY 11, no. 1 (January 1998): 178A-178A.


Lau, CL, Palmer, SM, D'Amico, TA, Tapson, VF, and Davis, RD. "Lung transplantation at Duke University Medical Center." Clin Transpl (1998): 327-340.


McAdams, HP, Palmer, SM, and Tapson, VF. "Virtual bronchoscopy for non-invasive assessment of bronchial anastomotic complications in lung transplant recipients." November 1997.


Palmer, SM, Miralles, AP, and Tapson, VF. "Sarcoidosis." N Engl J Med 337, no. 11 (September 11, 1997): 790-. (Letter)


Palmer, SM, Kanj, SS, Davis, RD, and Tapson, VF. "A case of disseminated infection with Nocardia brasiliensis in a lung transplant recipient." Transplantation 63, no. 8 (April 1997): 1189-1190.

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