Sin Tiong Ong, MBBCh

Associate Professor of Medicine
Campus mail 406 Seeley Mudd Bldg, Box 3406, Durham, NC 27710
Email address sintiong.ong@duke-nus.edu.sg

Education and Training

  • Resident, Medicine, University of California at Irvine, 1997 - 1999
  • Fellow, Hematology, Oncology, University of Chicago, 1993 - 1997
  • Resident, National University Hospital (Singapore), 1991 - 1993
  • M.B.B.Ch., University of Cambridge (UK), 1987

Publications

Prabhu, S, Saadat, D, Zhang, M, Halbur, L, Fruehauf, JP, and Ong, ST. "A novel mechanism for Bcr-Abl action: Bcr-Abl-mediated induction of the eIF4F translation initiation complex and mRNA translation." Oncogene 26, no. 8 (February 2007): 1188-1200.

PMID
16936779
Full Text

Arechiga, AF, Bell, BD, Leverrier, S, Weist, BM, Porter, M, Wu, Z, Kanno, Y, Ramos, SJ, Ong, ST, Siegel, R, and Walsh, CM. "A Fas-associated death domain protein/caspase-8-signaling axis promotes S-phase entry and maintains S6 kinase activity in T cells responding to IL-2 1." Journal of Immunology 179, no. 8 (2007): 5291-5300.

PMID
17911615
Scholars@Duke

Moore, JC, Dennehey, CF, Anavim, A, Kong, KM, and Ong, ST. "Multiple joint effusions associated with high-dose imatinib therapy in a patient with chronic myelogenous leukaemia." European Journal of Haematology 76, no. 5 (2006): 444-446.

PMID
16548915
Full Text

Ong, ST, Ly, C, Nguyen, M, Brightman, BK, and Fan, H. "Expression profiling of a transformed thymocyte cell line undergoing maturation in vitro identifies multiple genes involved in positive selection." Cellular Immunology 221, no. 1 (2003): 64-79.

PMID
12742383
Full Text

Ly, C, Arechiga, AF, Melo, JV, Walsh, CM, and Ong, ST. "Bcr-Abl kinase modulates the translation regulators ribosomal protein S6 and 4E-BP1 in chronic myelogenous leukemia cells via the mammalian target of rapamycin." Cancer Research 63, no. 18 (2003): 5716-5722.

PMID
14522890
Scholars@Duke

Peters, UR, Hasse, U, Oppliger, E, Tschan, M, Ong, ST, Rassool, FV, Borisch, B, Tobler, A, and Fey, MF. "Aberrant FHIT mRNA transcripts are present in malignant and normal haematopoiesis, but absence of FHIT protein is restricted to leukaemia." Oncogene 18, no. 1 (1999): 79-85.

PMID
9926922
Full Text

Ong, ST, Hackbarth, ML, Degenstein, LC, Baunoch, DA, Anastasi, J, and McKeithan, TW. "Lymphadenopathy, splenomegaly, and altered immunoglobulin production in BCL3 transgenic mice." Oncogene 16, no. 18 (1998): 2333-2343.

PMID
9620550
Scholars@Duke

Ong, ST, and Beau, MML. "Chromosomal abnormalities and molecular genetics of non-Hodgkin's lymphoma." Seminars in Oncology 25, no. 4 (1998): 447-460.

PMID
9728595
Scholars@Duke

Ong, ST, Fong, KM, Bader, SA, Minna, JD, Le Beau, MM, McKeithan, TW, and Rassool, FV. "Precise localization of the FHIT gene to the common fragile site at 3p14.2 (FRA3B) and characterization of homozygous deletions within FRA3B that affect FHIT transcription in tumor cell lines." Genes, chromosomes & cancer 20, no. 1 (September 1997): 16-23.

PMID
9290949
Full Text

Ong, ST, Fong, KM, Bader, SA, Minna, JD, Beau, MML, McKeithan, TW, and Rassool, FV. "Precise localization of the FHIT gene to the common fragile site at 3p14.2 (FRA3B) and characterization of homozygous deletions within FRA3B that affect FHIT transcription in tumor cell lines." Genes Chromosomes and Cancer 20, no. 1 (1997): 16-23.

Full Text

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