Steven Patierno, PhD

Professor of Medicine
Professor of Pharmacology and Cancer Biology
Professor in Family Medicine and Community Health
Core Faculty Member, Duke-Margolis Center for Health Policy
Member of the Duke Cancer Institute
Campus mail 10 Bryan Searle Drive, Seeley Mudd Building, Suite 413, Durham, NC 27710
Phone (919) 613-5093
Email address steven.patierno@duke.edu

Patierno's current translational research interests are focused on the genomics molecular biology of cancer disparities, cancer biology, molecular pharmacology and targeted experimental therapeutics to control prostate, breast and lung tumor aggressiveness. He is an internationally recognized expert in cancer control, cancer causation and molecular carcinogenesis, which includes a broad spectrum of laboratory and population level research.   Patierno is also actively engaged in cancer health disparities and healthcare delivery research focused on patient navigation, survivorship, community-based interventions, mHealth, implementation sciences, cancer care economics, and policy.

Education and Training

  • Postdoctoral Training, Norris Comprehensive Cancer, University of Southern California, 1986 - 1988
  • Ph.D., University of Texas Medical School, Houston, 1985
  • B.S., University of Connecticut, 1981

Publications

Pratt-Chapman, Mandi, Melissa A. Simon, Angela K. Patterson, Betsy C. Risendal, and Steven Patierno. “Survivorship navigation outcome measures: a report from the ACS patient navigation working group on survivorship navigation.” Cancer 117, no. 15 Suppl (August 2011): 3575–84. https://doi.org/10.1002/cncr.26261.

PMID
21780092
Full Text

Jean-Pierre, Pascal, Kevin Fiscella, Karen M. Freund, Jack Clark, Julie Darnell, Alan Holden, Douglas Post, Steven R. Patierno, Paul C. Winters, and Paul C. Patient Navigation Research Program Group. “Structural and reliability analysis of a patient satisfaction with cancer-related care measure: a multisite patient navigation research program study.” Cancer 117, no. 4 (February 15, 2011): 854–61. https://doi.org/10.1002/cncr.25501.

PMID
20922802
Full Text

Kwabi-Addo, Bernard, Songping Wang, Woonbok Chung, Jaroslav Jelinek, Steven R. Patierno, Bi-Dar Wang, Ramez Andrawis, et al. “Identification of differentially methylated genes in normal prostate tissues from African American and Caucasian men.” Clin Cancer Res 16, no. 14 (July 15, 2010): 3539–47. https://doi.org/10.1158/1078-0432.CCR-09-3342.

PMID
20606036
Full Text

Chun, Gina, Dongsoon Bae, Kristen Nickens, Travis J. O’Brien, Steven R. Patierno, and Susan Ceryak. “Polo-like kinase 1 enhances survival and mutagenesis after genotoxic stress in normal cells through cell cycle checkpoint bypass.” Carcinogenesis 31, no. 5 (May 2010): 785–93. https://doi.org/10.1093/carcin/bgq014.

PMID
20089605
Full Text

Wang, Bi-Dar, Christina Leah B. Kline, Danielle M. Pastor, Thomas L. Olson, Bryan Frank, Truong Luu, Arun K. Sharma, et al. “Prostate apoptosis response protein 4 sensitizes human colon cancer cells to chemotherapeutic 5-FU through mediation of an NF kappaB and microRNA network.” Mol Cancer 9 (April 30, 2010): 98. https://doi.org/10.1186/1476-4598-9-98.

PMID
20433755
Full Text

Beaver, Laura M., Erik J. Stemmy, Arnold M. Schwartz, Jesse M. Damsker, Stephanie L. Constant, Susan M. Ceryak, and Steven R. Patierno. “Lung inflammation, injury, and proliferative response after repetitive particulate hexavalent chromium exposure.” Environ Health Perspect 117, no. 12 (December 2009): 1896–1902. https://doi.org/10.1289/ehp.0900715.

PMID
20049209
Full Text

Bianco, Fernando J., Benjamin R. McHone, Kristopher Wagner, Andre King, Jacqueline Burgess, Steve Patierno, and Thomas W. Jarrett. “Prevalence of erectile dysfunction in men screened for prostate cancer.” Urology 74, no. 1 (July 2009): 89–93. https://doi.org/10.1016/j.urology.2008.03.036.

PMID
19428072
Full Text

Lal, Madhu A., Dongsoon Bae, Tura C. Camilli, Steven R. Patierno, and Susan Ceryak. “AKT1 mediates bypass of the G1/S checkpoint after genotoxic stress in normal human cells.” Cell Cycle 8, no. 10 (May 15, 2009): 1589–1602. https://doi.org/10.4161/cc.8.10.8547.

PMID
19377290
Full Text

O’Brien, Travis J., Preston Witcher, Bradford Brooks, and Steven R. Patierno. “DNA polymerase zeta is essential for hexavalent chromium-induced mutagenesis.” Mutat Res 663, no. 1–2 (April 26, 2009): 77–83. https://doi.org/10.1016/j.mrfmmm.2009.01.012.

PMID
19428373
Full Text

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