Sudha Kaup Shenoy, PhD

Associate Professor in Medicine
Associate Professor in Cell Biology
Member of the Duke Cancer Institute
Campus mail 148-A CARL Bldg, Durham, NC 27710
Phone (919) 681-5061
Email address skshenoy@dm.duke.edu

Education and Training

  • Ph.D., Oklahoma State University at Stillwater, 1998

Publications

Ge, Lan, Sudha K. Shenoy, Robert J. Lefkowitz, and Kathryn DeFea. “Constitutive protease-activated receptor-2-mediated migration of MDA MB-231 breast cancer cells requires both beta-arrestin-1 and -2.” J Biol Chem 279, no. 53 (December 31, 2004): 55419–24. https://doi.org/10.1074/jbc.M410312200.

PMID
15489220
Full Text

Usui, Isao, Takeshi Imamura, Jie Huang, Hiroaki Satoh, Sudha K. Shenoy, Robert J. Lefkowitz, Christopher J. Hupfeld, and Jerrold M. Olefsky. “beta-arrestin-1 competitively inhibits insulin-induced ubiquitination and degradation of insulin receptor substrate 1.” Mol Cell Biol 24, no. 20 (October 2004): 8929–37. https://doi.org/10.1128/MCB.24.20.8929-8937.2004.

PMID
15456867
Full Text

Ahn, Seungkirl, Sudha K. Shenoy, Huijun Wei, and Robert J. Lefkowitz. “Differential kinetic and spatial patterns of beta-arrestin and G protein-mediated ERK activation by the angiotensin II receptor.” J Biol Chem 279, no. 34 (August 20, 2004): 35518–25. https://doi.org/10.1074/jbc.M405878200.

PMID
15205453
Full Text

Martin, Negin P., Robert J. Lefkowitz, and Sudha K. Shenoy. “Regulation of V2 vasopressin receptor degradation by agonist-promoted ubiquitination.” J Biol Chem 278, no. 46 (November 14, 2003): 45954–59. https://doi.org/10.1074/jbc.M308285200.

PMID
12960162
Full Text

Shenoy, Sudha K., and Robert J. Lefkowitz. “Multifaceted roles of beta-arrestins in the regulation of seven-membrane-spanning receptor trafficking and signalling.” Biochem J 375, no. Pt 3 (November 1, 2003): 503–15. https://doi.org/10.1042/BJ20031076.

PMID
12959637
Full Text

Wei, Huijun, Seungkirl Ahn, Sudha K. Shenoy, Sadashiva S. Karnik, László Hunyady, Louis M. Luttrell, and Robert J. Lefkowitz. “Independent beta-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2.” Proc Natl Acad Sci U S A 100, no. 19 (September 16, 2003): 10782–87. https://doi.org/10.1073/pnas.1834556100.

PMID
12949261
Full Text

Shenoy, Sudha K., and Robert J. Lefkowitz. “Trafficking patterns of beta-arrestin and G protein-coupled receptors determined by the kinetics of beta-arrestin deubiquitination.” J Biol Chem 278, no. 16 (April 18, 2003): 14498–506. https://doi.org/10.1074/jbc.M209626200.

PMID
12574160
Full Text

SHENOY, S. K. “Multifaceted roles of β-arrestins in the regulation of seven-transmembrane-spanning receptor trafficking and signaling.” Biochem J. 375 (2003): 503–15.

Scholars@Duke

Lin, Fang-Tsyr, Wei Chen, Sudha Shenoy, Mei Cong, Sabrina T. Exum, and Robert J. Lefkowitz. “Phosphorylation of beta-arrestin2 regulates its function in internalization of beta(2)-adrenergic receptors.” Biochemistry 41, no. 34 (August 27, 2002): 10692–99. https://doi.org/10.1021/bi025705n.

PMID
12186555
Full Text

Pages