Susan Bailey Gurley, MD, PhD

Associate Professor of Medicine
Associate Professor in Pharmacology and Cancer Biology
Campus mail 2nd Floor, Rm 2018 MSRB II, 106 Research Drive, Durham, NC 27710
Phone (919) 684-9788
Email address susan.gurley@duke.edu

Mouse models of hypertension and diabetic nephropathy.
(1) Mouse models of diabetes complications (AMDCC)
(2) Role of angiotensin II and AT receptors in renal proximal tubule
(3) Role of ACE2 in hypertension, renal funciton

Education and Training

  • Fellow In Nephrology, Medicine, Duke University, 2002 - 2005
  • Medical Resident, Medicine, Duke University, 1998 - 2001
  • M.D., Washington University, 1998
  • Ph.D., University of Mississippi, 1994

Publications

Scott-Emuakpor, J, Allot, E, Johnson, SA, Howard, LE, Macias, E, Freedland, SJ, and Gurley, SB. "Angiotensin receptor signaling and prostate tumor growth in mice." Journal of experimental therapeutics & oncology 11, no. 2 (September 2017): 107-115.

PMID
28976133
Scholars@Duke

Otaño-Rivera, V, Boakye, A, Grobe, N, Almutairi, MM, Kursan, S, Mattis, LK, Castrop, H, Gurley, SB, Elased, KM, Boivin, GP, and Di Fulvio, M. "A highly efficient strategy to determine genotypes of genetically-engineered mice using genomic DNA purified from hair roots." Laboratory animals 51, no. 2 (April 2017): 138-146.

PMID
27166392
Full Text

Hall, RK, Haines, C, Gorbatkin, SM, Schlanger, L, Shaban, H, Schell, JO, Gurley, SB, Colón-Emeric, CS, and Bowling, CB. "Incorporating Geriatric Assessment into a Nephrology Clinic: Preliminary Data from Two Models of Care." Journal of the American Geriatrics Society 64, no. 10 (October 2016): 2154-2158.

PMID
27377350
Full Text

Clotet, S, Soler, MJ, Rebull, M, Gimeno, J, Gurley, SB, Pascual, J, and Riera, M. "Gonadectomy prevents the increase in blood pressure and glomerular injury in angiotensin-converting enzyme 2 knockout diabetic male mice. Effects on renin-angiotensin system." Journal of hypertension 34, no. 9 (September 2016): 1752-1765.

PMID
27379538
Full Text

Zhang, J, Rudemiller, NP, Patel, MB, Wei, Q, Karlovich, NS, Jeffs, AD, Wu, M, Sparks, MA, Privratsky, JR, Herrera, M, Gurley, SB, Nedospasov, SA, and Crowley, SD. "Competing Actions of Type 1 Angiotensin II Receptors Expressed on T Lymphocytes and Kidney Epithelium during Cisplatin-Induced AKI." Journal of the American Society of Nephrology : JASN 27, no. 8 (August 2016): 2257-2264.

PMID
26744488
Full Text

Chen, D, Stegbauer, J, Sparks, MA, Kohan, D, Griffiths, R, Herrera, M, Gurley, SB, and Coffman, TM. "Impact of Angiotensin Type 1A Receptors in Principal Cells of the Collecting Duct on Blood Pressure and Hypertension." Hypertension (Dallas, Tex. : 1979) 67, no. 6 (June 2016): 1291-1297.

PMID
27141055
Full Text

Ortiz-Melo, DI, and Gurley, SB. "Angiotensin converting enzyme 2 and the kidney." Current opinion in nephrology and hypertension 25, no. 1 (January 2016): 59-66. (Review)

PMID
26575394
Full Text

Domenig, O, Manzel, A, Grobe, N, Königshausen, E, Kaltenecker, CC, Kovarik, JJ, Stegbauer, J, Gurley, SB, van Oyen, D, Antlanger, M, Bader, M, Motta-Santos, D, Santos, RA, Elased, KM, Säemann, MD, Linker, RA, and Poglitsch, M. "Neprilysin is a Mediator of Alternative Renin-Angiotensin-System Activation in the Murine and Human Kidney." Scientific Reports 6 (January 2016): 33678-.

PMID
27649628
Full Text

Sparks, MA, Stegbauer, J, Chen, D, Gomez, JA, Griffiths, RC, Azad, HA, Herrera, M, Gurley, SB, and Coffman, TM. "Vascular Type 1A Angiotensin II Receptors Control BP by Regulating Renal Blood Flow and Urinary Sodium Excretion." Journal of the American Society of Nephrology : JASN 26, no. 12 (December 2015): 2953-2962.

PMID
25855778
Full Text

Rotroff, DM, Shahin, MH, Gurley, SB, Zhu, H, Motsinger-Reif, A, Meisner, M, Beitelshees, AL, Fiehn, O, Johnson, JA, Elbadawi-Sidhu, M, Frye, RF, Gong, Y, Weng, L, Cooper-DeHoff, RM, and Kaddurah-Daouk, R. "Pharmacometabolomic Assessments of Atenolol and Hydrochlorothiazide Treatment Reveal Novel Drug Response Phenotypes." CPT: pharmacometrics & systems pharmacology 4, no. 11 (November 2015): 669-679.

PMID
26783503
Full Text

Pages