Susanna Naggie, MD

Associate Professor of Medicine
Member in the Duke Clinical Research Institute
Campus mail Dcri-2400 Pratt Street, Room 0311-BOX 3850, Durham, NC 27710
Phone (919) 684-2584
Email address susanna.naggie@duke.edu

Dr. Susanna Naggie completed her medical education at Johns Hopkins School of Medicine and her internal medicine training at Duke University Medical Center (DUMC), where she also served as a Chief Resident in Internal Medicine.  She completed her Infectious Diseases (ID) fellowship training at Duke and then joined the faculty in the Division of ID. She is an Associate Professor of Medicine with Tenure and currently holds joint appointments at the Duke Clinical Research Institute (DCRI, Director of ID Research), and at the Durham Veterans Affairs Medical Center (DVAMC). Dr. Naggie has dedicated her academic career to the care of patients with HIV and viral hepatitis, with a research program focused on understanding the mechanisms of accelerated liver fibrogenesis in this population and the extrahepatic health outcomes attributed to HCV in persons with HIV infection. In addition to her investigator-initiated research program, Dr. Naggie is also involved in multiple clinical trials and clinical registries with a particular focus on HIV and liver disease. She is the prior co-Chair of the AASLD/IDSA HCV Guidance Committee and is currently Chair of the AIDS Clinical Trials Group Viral Hepatitis Transformative Science Group Committee and a member of the DHHS Guidelines for the Use of Antiretroviral Agents in Adults and Adolescents Living with HIV and the CDC/NIH/IDSA-HIVMA Opportunistic Infections Guideline Committee. For the past two years Dr. Naggie has served as the Medical Director of the Duke Department of Medicine Clinical Research Unit.

Education and Training

  • Fellow in Infectious Diseases, Medicine, Duke University, 2007 - 2009
  • Chief Medical Resident - VAMC, Medicine, Duke University, 2006 - 2007
  • Medical Resident, Medicine, Duke University, 2002 - 2005
  • M.D., Johns Hopkins University, 2002

Publications

Naggie, Susanna, Meredith Clement, Sam Lusk, Anu Osinusi, Tiffany Himmel, Joseph E. Lucas, Will J. Thompson, et al. “Using Stepwise Pharmacogenomics and Proteomics to Predict Hepatitis C Treatment Response in Difficult to Treat Patient Populations..” Proteomics. Clinical Applications, July 30, 2018. https://doi.org/10.1002/prca.201800006.

PMID
30058111
Full Text

Naggie, Susanna, Marzena Swiderska-Syn, Steve Choi, Sam Lusk, Audrey Lan, Guido Ferrari, Wing-Kin Syn, Cynthia D. Guy, and Anna Mae Diehl. “Markers of Tissue Repair and Cellular Aging Are Increased in the Liver Tissue of Patients With HIV Infection Regardless of Presence of HCV Coinfection..” Open Forum Infectious Diseases 5, no. 7 (July 2018). https://doi.org/10.1093/ofid/ofy138.

PMID
29992177
Full Text

Clement, Meredith E., Lauren F. Collins, Julius M. Wilder, Michael Mugavero, Taryn Barker, and Susanna Naggie. “Hepatitis C Virus Elimination in the Human Immunodeficiency Virus-Coinfected Population: Leveraging the Existing Human Immunodeficiency Virus Infrastructure..” Infectious Disease Clinics of North America 32, no. 2 (June 2018): 407–23. https://doi.org/10.1016/j.idc.2018.02.005.

PMID
29778263
Full Text

Carlton-Smith, C., J. A. Holmes, S. Naggie, A. Lidofsky, G. M. Lauer, A. Y. Kim, R. T. Chung, and R. T. of the ACTG A5327 study group. “IFN-free therapy is associated with restoration of type I IFN response in HIV-1 patients with acute HCV infection who achieve SVR..” Journal of Viral Hepatitis 25, no. 5 (May 2018): 465–72. https://doi.org/10.1111/jvh.12836.

PMID
29193564
Full Text

Wilder, Julius M., Jia Yao, Makarushka Christina, Donna Evon, Michael W. Fried, Susanna Naggie, Andrew J. Muir, and Rae Jean Proeschold-Bell. “ASSOCIATIONS OF ALCOHOL CONSUMPTION MOTIVES WITH DEPRESSION AND PAIN AMONG INDIVIDUALS WITH HEPATITIS C.” In Gastroenterology, 154:S1121–22. W B SAUNDERS CO-ELSEVIER INC, 2018.

Scholars@Duke

Kleinstein, Sarah E., Patrick R. Shea, Luisa M. Stamm, Mark Sulkowski, David B. Goldstein, and Susanna Naggie. “Association of CYP2B6 Single-Nucleotide Polymorphisms Altering Efavirenz Metabolism With Hepatitis C Virus (HCV) Treatment Relapse Among Human Immunodeficiency Virus/HCV-Coinfected African Americans Receiving Ledipasvir/Sofosbuvir in the ION-4 Trial..” Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America, March 7, 2018. https://doi.org/10.1093/cid/cix1051.

PMID
29522085
Full Text

Okeke, Nwora Lance, Damian M. Craig, Michael J. Muehlbauer, Olga Ilkayeva, Meredith E. Clement, Susanna Naggie, and Svati H. Shah. “Metabolites predict cardiovascular disease events in persons living with HIV: a pilot case-control study..” Metabolomics : Official Journal of the Metabolomic Society 14, no. 3 (March 2018). https://doi.org/10.1007/s11306-018-1318-z.

PMID
30760970
Full Text

Clement, Meredith E., Li Lin, Ann Marie Navar, Nwora Lance Okeke, Susanna Naggie, and Pamela S. Douglas. “Lower likelihood of cardiac procedures after acute coronary syndrome in patients with human immunodeficiency virus/acquired immunodeficiency syndrome..” Medicine 97, no. 6 (February 2018). https://doi.org/10.1097/MD.0000000000009849.

PMID
29419696
Full Text

Collins, Lauren F., Austin Chan, Jiayin Zheng, Shein-Chung Chow, Julius M. Wilder, Andrew J. Muir, and Susanna Naggie. “Direct-Acting Antivirals Improve Access to Care and Cure for Patients With HIV and Chronic HCV Infection..” Open Forum Infectious Diseases 5, no. 1 (January 2018). https://doi.org/10.1093/ofid/ofx264.

PMID
29308413
Full Text

Morgan, Jake R., Arthur Y. Kim, Susanna Naggie, and Benjamin P. Linas. “The Effect of Shorter Treatment Regimens for Hepatitis C on Population Health and Under Fixed Budgets..” Open Forum Infectious Diseases 5, no. 1 (January 2018). https://doi.org/10.1093/ofid/ofx267.

PMID
29354660
Full Text

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