Susanna Naggie, MD

Professor of Medicine
Vice Dean for Clinical Research
Member in the Duke Clinical Research Institute
Campus mail 300 West Morgan St, Suite 800, Durham, NC 27701
Phone (919) 684-2584
Email address susanna.naggie@duke.edu

Dr. Susanna Naggie completed her medical education at Johns Hopkins School of Medicine and her internal medicine training at Duke University Medical Center (DUMC), where she also served as a Chief Resident in Internal Medicine.  She completed her Infectious Diseases (ID) fellowship training at Duke and then joined the faculty in the Division of ID. She is an Associate Professor of Medicine with Tenure and currently holds joint appointments at the Duke Clinical Research Institute (DCRI, Director of ID Research), and at the Durham Veterans Affairs Medical Center (DVAMC). Dr. Naggie has dedicated her academic career to the care of patients with HIV and viral hepatitis, with a research program focused on understanding the mechanisms of accelerated liver fibrogenesis in this population and the extrahepatic health outcomes attributed to HCV in persons with HIV infection. In addition to her investigator-initiated research program, Dr. Naggie is also involved in multiple clinical trials and clinical registries with a particular focus on HIV and liver disease. She is the prior co-Chair of the AASLD/IDSA HCV Guidance Committee and is currently Chair of the AIDS Clinical Trials Group Viral Hepatitis Transformative Science Group Committee and a member of the DHHS Guidelines for the Use of Antiretroviral Agents in Adults and Adolescents Living with HIV and the CDC/NIH/IDSA-HIVMA Opportunistic Infections Guideline Committee. For the past two years Dr. Naggie has served as the Medical Director of the Duke Department of Medicine Clinical Research Unit.

Education and Training

  • Fellow in Infectious Diseases, Medicine, Duke University, 2007 - 2009
  • Chief Medical Resident - VAMC, Medicine, Duke University, 2006 - 2007
  • Medical Resident, Medicine, Duke University, 2002 - 2005
  • M.D., Johns Hopkins University, 2002

Publications

Naggie, Susanna, and Charles Hicks. “Protease inhibitor-based antiretroviral therapy in treatment-naive HIV-1-infected patients: the evidence behind the options.” J Antimicrob Chemother 65, no. 6 (June 2010): 1094–99. https://doi.org/10.1093/jac/dkq130.

PMID
20418273
Full Text

Rallón, Norma I., Susanna Naggie, José M. Benito, José Medrano, Clara Restrepo, David Goldstein, Kevin V. Shianna, et al. “Association of a single nucleotide polymorphism near the interleukin-28B gene with response to hepatitis C therapy in HIV/hepatitis C virus-coinfected patients.” Aids 24, no. 8 (May 15, 2010): F23–29. https://doi.org/10.1097/QAD.0b013e3283391d6d.

PMID
20389235
Full Text

Kutty, Preeta K., Christopher W. Woods, Arlene C. Sena, Stephen R. Benoit, Susanna Naggie, Joyce Frederick, Sharon Evans, Jeffery Engel, and L Clifford McDonald. “Risk factors for and estimated incidence of community-associated Clostridium difficile infection, North Carolina, USA.” Emerg Infect Dis 16, no. 2 (February 2010): 197–204. https://doi.org/10.3201/eid1602.090953.

PMID
20113547
Full Text

Naggie, Susanna, Tsung Hseih, Jennifer Reckleff, Joe Castellano, and Charles B. Hicks. “Treatment and CD4+ T cell count recovery among antiretroviral therapy-naive patients with HIV/AIDS.” Clin Infect Dis 49, no. 10 (November 15, 2009): 1619–20. https://doi.org/10.1086/644776.

PMID
19857170
Full Text

Kutty, Preeta K., Stephen R. Benoit, Christopher W. Woods, Arlene C. Sena, Susanna Naggie, Joyce Frederick, John Engemann, et al. “Assessment of Clostridium difficile-associated disease surveillance definitions, North Carolina, 2005.” Infect Control Hosp Epidemiol 29, no. 3 (March 2008): 197–202. https://doi.org/10.1086/528813.

PMID
18241032
Full Text

Pham, M. Q., S. Naggie, M. Wier, H. J. Cha, and W. E. Bentley. “Human interleukin-2 production in insect (Trichoplusia ni) larvae: effects and partial control of proteolysis.” Biotechnol Bioeng 62, no. 2 (January 20, 1999): 175–82. https://doi.org/10.1002/(sici)1097-0290(19990120)62:2<175::aid-bit7>3.0.co;2-j.

PMID
10099527
Full Text

Naggie, S., and W. E. Bentley. “Appearance of protease activities coincides with p10 and polyhedrin-driven protein production in the baculovirus expression system: effects on yield.” Biotechnol Prog 14, no. 2 (March 1998): 227–32. https://doi.org/10.1021/bp980002b.

PMID
9548773
Full Text

Naggie, S., Y. C. Hu, T. R. Pulliam-Holoman, and W. E. Bentley. “Substrate (gelatin) gel electrophoretic method for analysis of protease activity in insect (Sf-9) cells.” Biotechnology Techniques 11, no. 5 (January 1, 1997): 297–300. https://doi.org/10.1023/A:1018411210412.

Full Text

Pages