Cardiology

Svati Hasmukh Shah, MD

Associate Professor of Medicine
Member in the Duke Clinical Research Institute
Member of Duke Molecular Physiology Institute
Campus mail DUMC Box 3445, Durham, NC 27710
Phone (919) 684-1808
Email address svati.shah@duke.edu
In Their Words

Education and Training

  • Fellow in Cardiology, Medicine, Duke University, 2001 - 2005
  • Medical Resident, Medicine, Children's Hospital Boston, 1998 - 2001
  • M.D., University of Washington, 1998
  • M.H.S., Johns Hopkins University, 1994

Grants

Publications

Christophersen, IE, Rienstra, M, Roselli, C, Yin, X, Geelhoed, B, Barnard, J, Lin, H, Arking, DE, Smith, AV, Albert, CM, Chaffin, M, Tucker, NR, Li, M, Klarin, D, Bihlmeyer, NA, Low, S-K, Weeke, PE, Müller-Nurasyid, M, Smith, JG, Brody, JA, Niemeijer, MN, Dörr, M, Trompet, S, Huffman, J, Gustafsson, S, Schurmann, C, Kleber, ME, Lyytikäinen, L-P, Seppälä, I, Malik, R, Horimoto, ARVR, Perez, M, Sinisalo, J, Aeschbacher, S, Thériault, S, Yao, J, Radmanesh, F, Weiss, S, Teumer, A, Choi, SH, Weng, L-C, Clauss, S, Deo, R, Rader, DJ, Shah, SH, Sun, A, Hopewell, JC, Debette, S, Chauhan, G, Yang, Q, Worrall, BB, Paré, G, Kamatani, Y, Hagemeijer, YP, Verweij, N, Siland, JE, Kubo, M, Smith, JD, Van Wagoner, DR, Bis, JC, Perz, S, Psaty, BM, Ridker, PM, Magnani, JW, Harris, TB, Launer, LJ, Shoemaker, MB, Padmanabhan, S, Haessler, J, Bartz, TM, Waldenberger, M, Lichtner, P, Arendt, M, Krieger, JE, Kähönen, M, Risch, L, Mansur, AJ, Peters, A, Smith, BH, Lind, L, Scott, SA, Lu, Y, Bottinger, EB, Hernesniemi, J, Lindgren, CM, Wong, JA, Huang, J, Eskola, M, Morris, AP, Ford, I, Reiner, AP, Delgado, G, Chen, LY, Chen, Y-DI, Sandhu, RK, Li, M, Boerwinkle, E, Eisele, L, Lannfelt, L, Rost, N, Anderson, CD, Taylor, KD, Campbell, A, Magnusson, PK, Porteous, D, Hocking, LJ, Vlachopoulou, E, Pedersen, NL, Nikus, K, Orho-Melander, M, Hamsten, A, Heeringa, J, Denny, JC, Kriebel, J, Darbar, D, Newton-Cheh, C, Shaffer, C, Macfarlane, PW, Heilmann-Heimbach, S, Almgren, P, Huang, PL, Sotoodehnia, N, Soliman, EZ, Uitterlinden, AG, Hofman, A, Franco, OH, Völker, U, Jöckel, K-H, Sinner, MF, Lin, HJ, Guo, X, METASTROKE Consortium of the ISGC, , Neurology Working Group of the CHARGE Consortium, , Dichgans, M, Ingelsson, E, Kooperberg, C, Melander, O, Loos, RJF, Laurikka, J, Conen, D, Rosand, J, van der Harst, P, Lokki, M-L, Kathiresan, S, Pereira, A, Jukema, JW, Hayward, C, Rotter, JI, März, W, Lehtimäki, T, Stricker, BH, Chung, MK, Felix, SB, Gudnason, V, Alonso, A, Roden, DM, Kääb, S, Chasman, DI, Heckbert, SR, Benjamin, EJ, Tanaka, T, Lunetta, KL, Lubitz, SA, Ellinor, PT, and AFGen Consortium, . "Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation." Nature Genetics 49, no. 6 (June 2017): 946-952.

PMID
28416818
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Guimarães, PO, Sun, J-L, Kragholm, K, Shah, SH, Pieper, KS, Kraus, WE, Hauser, ER, Granger, CB, Kristin Newby, L, MURDOCK Horizon 1 Cardiovascular Study Investigators Durham, and NC, . "Corrigendum to 'Association of Standard Clinical and Laboratory Variables with Red Blood Cell Distribution Width (RDW)'[Am. Heart J. (2016) 22-28]." American Heart Journal 188 (June 2017): 196-null.

PMID
28577677
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Mirowsky, JE, Devlin, RB, Diaz-Sanchez, D, Cascio, W, Grabich, SC, Haynes, C, Blach, C, Hauser, ER, Shah, S, Kraus, W, Olden, K, and Neas, L. "A novel approach for measuring residential socioeconomic factors associated with cardiovascular and metabolic health." Journal of Exposure Science & Environmental Epidemiology 27, no. 3 (May 2017): 281-289.

PMID
27649842
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Stitziel, NO, Khera, AV, Wang, X, Bierhals, AJ, Vourakis, AC, Sperry, AE, Natarajan, P, Klarin, D, Emdin, CA, Zekavat, SM, Nomura, A, Erdmann, J, Schunkert, H, Samani, NJ, Kraus, WE, Shah, SH, Yu, B, Boerwinkle, E, Rader, DJ, Gupta, N, Frossard, PM, Rasheed, A, Danesh, J, Lander, ES, Gabriel, S, Saleheen, D, Musunuru, K, Kathiresan, S, and PROMIS and Myocardial Infarction Genetics Consortium Investigators, . "ANGPTL3 Deficiency and Protection Against Coronary Artery Disease." Journal of the American College of Cardiology 69, no. 16 (April 3, 2017): 2054-2063.

PMID
28385496
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Cheng, S, Shah, SH, Corwin, EJ, Fiehn, O, Fitzgerald, RL, Gerszten, RE, Illig, T, Rhee, EP, Srinivas, PR, Wang, TJ, Jain, M, American Heart Association Council on Functional Genomics and Translational Biology, Council on Cardiovascular and Stroke Nursing, Council on Clinical Cardiology, and and Stroke Council, . "Potential Impact and Study Considerations of Metabolomics in Cardiovascular Health and Disease: A Scientific Statement From the American Heart Association." Circulation. Cardiovascular Genetics 10, no. 2 (April 2017). (Review)

PMID
28360086
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Luo, N, Craig, D, Ilkayeva, O, Muehlbauer, M, Kraus, WE, Newgard, CB, Shah, SH, and Rajagopal, S. "Plasma acylcarnitines are associated with pulmonary hypertension." Pulmonary Circulation 7, no. 1 (March 2017): 211-218.

PMID
28680580
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de Denus, S, Rouleau, JL, Mann, DL, Huggins, GS, Cappola, TP, Shah, SH, Keleti, J, Zada, YF, Provost, S, Bardhadi, A, Phillips, MS, Normand, V, Mongrain, I, and Dubé, M-P. "A pharmacogenetic investigation of intravenous furosemide in decompensated heart failure: a meta-analysis of three clinical trials." March 2017.

PMID
26927285
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Voora, D, Coles, A, Lee, KL, Hoffmann, U, Wingrove, JA, Rhees, B, Huang, L, Daniels, SE, Monane, M, Rosenberg, S, Shah, SH, Kraus, WE, Ginsburg, GS, and Douglas, PS. "An age- and sex-specific gene expression score is associated with revascularization and coronary artery disease: Insights from the Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE) trial." American Heart Journal 184 (February 2017): 133-140.

PMID
28224927
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Wang, H, Pun, PH, Kwee, L, Craig, D, Haynes, C, Chryst-Ladd, M, Svetkey, LP, Patel, UD, Hauser, ER, Pollak, MR, Kraus, WE, and Shah, SH. "Apolipoprotein L1 Genetic Variants Are Associated with Chronic Kidney Disease but Not with Cardiovascular Disease in a Population Referred for Cardiac Catheterization." Cardiorenal Medicine 7, no. 2 (February 2017): 96-103.

PMID
28611783
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Marouli, E, Graff, M, Medina-Gomez, C, Lo, KS, Wood, AR, Kjaer, TR, Fine, RS, Lu, Y, Schurmann, C, Highland, HM, Rüeger, S, Thorleifsson, G, Justice, AE, Lamparter, D, Stirrups, KE, Turcot, V, Young, KL, Winkler, TW, Esko, T, Karaderi, T, Locke, AE, Masca, NGD, Ng, MCY, Mudgal, P, Rivas, MA, Vedantam, S, Mahajan, A, Guo, X, Abecasis, G, Aben, KK, Adair, LS, Alam, DS, Albrecht, E, Allin, KH, Allison, M, Amouyel, P, Appel, EV, Arveiler, D, Asselbergs, FW, Auer, PL, Balkau, B, Banas, B, Bang, LE, Benn, M, Bergmann, S, Bielak, LF, Blüher, M, Boeing, H, Boerwinkle, E, Böger, CA, Bonnycastle, LL, Bork-Jensen, J, Bots, ML, Bottinger, EP, Bowden, DW, Brandslund, I, Breen, G, Brilliant, MH, Broer, L, Burt, AA, Butterworth, AS, Carey, DJ, Caulfield, MJ, Chambers, JC, Chasman, DI, Chen, Y-DI, Chowdhury, R, Christensen, C, Chu, AY, Cocca, M, Collins, FS, Cook, JP, Corley, J, Galbany, JC, Cox, AJ, Cuellar-Partida, G, Danesh, J, Davies, G, de Bakker, PIW, de Borst, GJ, de Denus, S, de Groot, MCH, de Mutsert, R, Deary, IJ, Dedoussis, G, Demerath, EW, den Hollander, AI, Dennis, JG, Di Angelantonio, E, Drenos, F, Du, M, Dunning, AM, Easton, DF, Ebeling, T, Edwards, TL, Ellinor, PT, Elliott, P, Evangelou, E, Farmaki, A-E, Faul, JD, Feitosa, MF, Feng, S, Ferrannini, E, Ferrario, MM, Ferrieres, J, Florez, JC, Ford, I, Fornage, M, Franks, PW, Frikke-Schmidt, R, Galesloot, TE, Gan, W, Gandin, I, Gasparini, P, Giedraitis, V, Giri, A, Girotto, G, Gordon, SD, Gordon-Larsen, P, Gorski, M, Grarup, N, Grove, ML, Gudnason, V, Gustafsson, S, Hansen, T, Harris, KM, Harris, TB, Hattersley, AT, Hayward, C, He, L, Heid, IM, Heikkilä, K, Helgeland, Ø, Hernesniemi, J, Hewitt, AW, Hocking, LJ, Hollensted, M, Holmen, OL, Hovingh, GK, Howson, JMM, Hoyng, CB, Huang, PL, Hveem, K, Ikram, MA, Ingelsson, E, Jackson, AU, Jansson, J-H, Jarvik, GP, Jensen, GB, Jhun, MA, Jia, Y, Jiang, X, Johansson, S, Jørgensen, ME, Jørgensen, T, Jousilahti, P, Jukema, JW, Kahali, B, Kahn, RS, Kähönen, M, Kamstrup, PR, Kanoni, S, Kaprio, J, Karaleftheri, M, Kardia, SLR, Karpe, F, Kee, F, Keeman, R, Kiemeney, LA, Kitajima, H, Kluivers, KB, Kocher, T, Komulainen, P, Kontto, J, Kooner, JS, Kooperberg, C, Kovacs, P, Kriebel, J, Kuivaniemi, H, Küry, S, Kuusisto, J, La Bianca, M, Laakso, M, Lakka, TA, Lange, EM, Lange, LA, Langefeld, CD, Langenberg, C, Larson, EB, Lee, I-T, Lehtimäki, T, Lewis, CE, Li, H, Li, J, Li-Gao, R, Lin, H, Lin, L-A, Lin, X, Lind, L, Lindström, J, Linneberg, A, Liu, Y, Liu, Y, Lophatananon, A, Luan, J, Lubitz, SA, Lyytikäinen, L-P, Mackey, DA, Madden, PAF, Manning, AK, Männistö, S, Marenne, G, Marten, J, Martin, NG, Mazul, AL, Meidtner, K, Metspalu, A, Mitchell, P, Mohlke, KL, Mook-Kanamori, DO, Morgan, A, Morris, AD, Morris, AP, Müller-Nurasyid, M, Munroe, PB, Nalls, MA, Nauck, M, Nelson, CP, Neville, M, Nielsen, SF, Nikus, K, Njølstad, PR, Nordestgaard, BG, Ntalla, I, O'Connel, JR, Oksa, H, Loohuis, LMO, Ophoff, RA, Owen, KR, Packard, CJ, Padmanabhan, S, Palmer, CNA, Pasterkamp, G, Patel, AP, Pattie, A, Pedersen, O, Peissig, PL, Peloso, GM, Pennell, CE, Perola, M, Perry, JA, Perry, JRB, Person, TN, Pirie, A, Polasek, O, Posthuma, D, Raitakari, OT, Rasheed, A, Rauramaa, R, Reilly, DF, Reiner, AP, Renström, F, Ridker, PM, Rioux, JD, Robertson, N, Robino, A, Rolandsson, O, Rudan, I, Ruth, KS, Saleheen, D, Salomaa, V, Samani, NJ, Sandow, K, Sapkota, Y, Sattar, N, Schmidt, MK, Schreiner, PJ, Schulze, MB, Scott, RA, Segura-Lepe, MP, Shah, S, Sim, X, Sivapalaratnam, S, Small, KS, Smith, AV, Smith, JA, Southam, L, Spector, TD, Speliotes, EK, Starr, JM, Steinthorsdottir, V, Stringham, HM, Stumvoll, M, Surendran, P, 't Hart, LM, Tansey, KE, Tardif, J-C, Taylor, KD, Teumer, A, Thompson, DJ, Thorsteinsdottir, U, Thuesen, BH, Tönjes, A, Tromp, G, Trompet, S, Tsafantakis, E, Tuomilehto, J, Tybjaerg-Hansen, A, Tyrer, JP, Uher, R, Uitterlinden, AG, Ulivi, S, van der Laan, SW, Van Der Leij, AR, van Duijn, CM, van Schoor, NM, van Setten, J, Varbo, A, Varga, TV, Varma, R, Edwards, DRV, Vermeulen, SH, Vestergaard, H, Vitart, V, Vogt, TF, Vozzi, D, Walker, M, Wang, F, Wang, CA, Wang, S, Wang, Y, Wareham, NJ, Warren, HR, Wessel, J, Willems, SM, Wilson, JG, Witte, DR, Woods, MO, Wu, Y, Yaghootkar, H, Yao, J, Yao, P, Yerges-Armstrong, LM, Young, R, Zeggini, E, Zhan, X, Zhang, W, Zhao, JH, Zhao, W, Zheng, H, Zhou, W, EPIC-InterAct Consortium, , CHD Exome+ Consortium, , ExomeBP Consortium, , T2D-Genes Consortium, , GoT2D Genes Consortium, , Global Lipids Genetics Consortium, , ReproGen Consortium, , MAGIC Investigators, , Rotter, JI, Boehnke, M, Kathiresan, S, McCarthy, MI, Willer, CJ, Stefansson, K, Borecki, IB, Liu, DJ, North, KE, Heard-Costa, NL, Pers, TH, Lindgren, CM, Oxvig, C, Kutalik, Z, Rivadeneira, F, Loos, RJF, Frayling, TM, Hirschhorn, JN, Deloukas, P, and Lettre, G. "Rare and low-frequency coding variants alter human adult height." Nature 542, no. 7640 (February 2017): 186-190.

PMID
28146470
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