Syed Yousuf Zafar, MD

Associate Professor of Medicine
Associate Professor in the Sanford School of Public Policy
Affiliate, Duke Global Health Institute
Member of the Duke Cancer Institute
Member in the Duke Clinical Research Institute
Campus mail Duke Box 3505, Durham, NC 27710
Phone (919) 684-8111
Email address yousuf.zafar@duke.edu

Dr. Zafar is a health services researcher with a focus in improving care delivery for patients with advanced cancer. He has obtained advanced training in health services research and has participated in single-institution, multi-institution and national studies focusing on access to care, cost of care, and comparative effectiveness of care delivery between health systems. His primary area of interest is in the cost of cancer care. He has conducted institutional and national studies on how treatment-related costs impact cancer patients' experience. His current work in this arena is focused on patient preferences regarding cost-related communication and decision-making.

A second field of interest is palliative care. Dr. Zafar has collaborated with national and international palliative care leaders to improve the design and delivery of palliative care in cancer clinical trials. Methodologically, this work has centered around systematic literature reviews, iterative surveys, and prospective clinical trials.

Dr. Zafar is a member of the American Society of Clinical Oncology’s Health Disparities and Clinical Practice Guideline Committees. He is a member of the Alliance for Clinical Trials in Oncology's Health Disparities and Health Outcomes Committees. Dr. Zafar's work has been funded by the American Cancer Society, the HealthWell Foundation, the Duke Cancer Prevention and Control Program, the Duke Clinical Research Institute, and the CALGB Foundation.

In Their Words

Education and Training

  • Fellow in Hematology-Oncology, Medicine, Duke University, 2005 - 2008
  • Resident, Medicine, University of Cincinnati, 2002 - 2005
  • M.D., University of Toledo, 2002

Publications

Altomare, I, Irwin, B, Zafar, SY, Houck, K, Maloney, B, Greenup, R, and Peppercorn, J. "Physician Experience and Attitudes Toward Addressing the Cost of Cancer Care." Journal of oncology practice 12, no. 3 (March 2016): e281-248.

PMID
26883407
Full Text

Zafar, SY. "Abstract IA09: Intervening on the financial toxicity of cancer care." March 2016.

Full Text

Roe, MT, Cyr, DD, Eckart, D, Schulte, PJ, Morse, MA, Blackwell, KL, Ready, NE, Zafar, SY, Beaven, AW, Strickler, JH, Onken, JE, Winters, KJ, Houterloot, L, Zamoryakhin, D, Wiviott, SD, White, HD, Prabhakaran, D, Fox, KAA, Armstrong, PW, Ohman, EM, and TRILOGY ACS Investigators, . "Ascertainment, classification, and impact of neoplasm detection during prolonged treatment with dual antiplatelet therapy with prasugrel vs. clopidogrel following acute coronary syndrome." European heart journal 37, no. 4 (January 2016): 412-422.

PMID
26637834
Full Text

Kircher, SM, Meeker, CR, Nimeiri, H, Geynisman, DM, Zafar, SY, Shankaran, V, de Souza, J, and Wong, Y-N. "The Parity Paradigm: Can Legislation Help Reduce the Cost Burden of Oral Anticancer Medications?." Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 19, no. 1 (January 2016): 88-98.

PMID
26797241
Full Text

Deming, D, Uboha, N, Zafar, SY, Rosenberg, S, Bassetti, M, Glasgow, S, Borden, EC, and Lubner, S. "Adjuvant Chemotherapy for Stage II Rectal Cancer." Seminars in oncology 42, no. 6 (December 2015): e99-107. (Review)

PMID
26615141
Full Text

Zafar, SY, Chino, F, Ubel, PA, Rushing, C, Samsa, G, Altomare, I, Nicolla, J, Schrag, D, Tulsky, JA, Abernethy, AP, and Peppercorn, JM. "The utility of cost discussions between patients with cancer and oncologists." The American journal of managed care 21, no. 9 (September 2015): 607-615.

PMID
26618364
Scholars@Duke

Nipp, RD, Currow, DC, Cherny, NI, Strasser, F, Abernethy, AP, and Zafar, SY. "Best supportive care in clinical trials: review of the inconsistency in control arm design." British journal of cancer 113, no. 1 (June 11, 2015): 6-11. (Review)

PMID
26068397
Full Text

Kutner, JS, Blatchford, PJ, Taylor, DH, Ritchie, CS, Bull, JH, Fairclough, DL, Hanson, LC, LeBlanc, TW, Samsa, GP, Wolf, S, Aziz, NM, Currow, DC, Ferrell, B, Wagner-Johnston, N, Zafar, SY, Cleary, JF, Dev, S, Goode, PS, Kamal, AH, Kassner, C, Kvale, EA, McCallum, JG, Ogunseitan, AB, Pantilat, SZ, Portenoy, RK, Prince-Paul, M, Sloan, JA, Swetz, KM, Von Gunten, CF, and Abernethy, AP. "Safety and benefit of discontinuing statin therapy in the setting of advanced, life-limiting illness: a randomized clinical trial." JAMA internal medicine 175, no. 5 (May 2015): 691-700.

PMID
25798575
Full Text

Zafar, SY, Ubel, PA, Tulsky, JA, and Pollak, KI. "Cost-related health literacy: a key component of high-quality cancer care." Journal of oncology practice 11, no. 3 (May 2015): 171-173.

PMID
25829522
Full Text

Zafar, SY, McNeil, RB, Thomas, CM, Lathan, CS, Ayanian, JZ, and Provenzale, D. "Population-based assessment of cancer survivors' financial burden and quality of life: a prospective cohort study." Journal of oncology practice 11, no. 2 (March 2015): 145-150.

PMID
25515717
Full Text

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