Thomas William LeBlanc, MD

Associate Professor of Medicine
Associate Professor in Population Health Sciences
Member of the Duke Cancer Institute
Campus mail 2424 Erwin Road, Suite 602, Durham, NC 27705
Phone (919) 668-2115
Email address thomas.leblanc@duke.edu

I am a medical oncologist, palliative care physician, and patient experience researcher.  My clinical practice focuses on the care of patients with hematologic malignancies, with a particular emphasis on myeloid conditions and acute leukemias including acute myeloid leukemia (AML), acute lymphocytic leukemia (ALL), myelodysplastic syndromes (MDS), and myeloproliferative neoplasms (MPNs / MPDs, CML).  

As founding Director of the Duke Cancer Patient Experience Research Program (CPEP), my research investigates common issues faced by people with cancer, including issues of symptom burden, quality of life, psychological distress, prognostic understanding, and treatment decision-making. This work aims to improve patients' experiences living with serious illnesses like blood cancers, including the integration of specialist palliative care services to provide an extra layer of support along with their comprehensive cancer care. More broadly, our team in CPEP conducts various studies of patient experience and outcomes issues in oncology, including retrospective chart review studies, comparative effectiveness work, prospective observational studies and registries, and qualitative research, along with efforts to facilitate the integration of patient-generated health data (PGHD) into routine cancer care processes, such as with electronic patient-reported outcome measures (ePROs) and other mobile health interventions (mHealth). 

This work has led to recognition as an "Inspirational Leader under 40" by the American Academy of Hospice and Palliative Medicine (AAHPM), "Fellow" status from the Academy in 2016, the 2018 international "Clinical Impact Award" from the European Association for Palliative Care, and the AAHPM "Early Career Investigator" award in 2020. I served as 2017-18 Chair of the ASCO Ethics Committee, and currently Chair the Scientific Review Committee of the NIH/NINR-funded Palliative Care Research Cooperative Group (PCRC; www.palliativecareresearch.org). I have served on various national guideline panels for AML and for palliative/supportive care issues in oncology, and was inducted as a Fellow of the American Society of Clinical Oncology (FASCO) in 2021. To date I have published over 150 Medline-indexed articles, and several chapters in prominent textbooks of oncology and palliative medicine.

Education and Training

  • Fellow, Medical Oncology, Duke University School of Medicine, 2012 - 2013
  • Fellowship, Hospice And Palliative Medicine, Duke University School of Medicine, 2011 - 2012
  • Chief Medical Resident, Duke University School of Medicine, 2010 - 2011
  • Resident, Duke University School of Medicine, 2007 - 2009
  • Intern, Duke University School of Medicine, 2006 - 2007
  • M.D., Duke University, 2006

Publications

Leblanc, Thomas W., Susan Morris, Michael Hooks, Susan C. Locke, and Areej El-Jawahri. “Patient Experiences with Liposomal Daunorubicin and Cytarabine (CPX-351) Versus Conventional Induction Regimens: An Analysis of Patient-Reported Outcomes Data from a Prospective Trial.” In Blood, 136:29–30. American Society of Hematology, 2020. https://doi.org/10.1182/blood-2020-139727.

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Pabon, Cindy M., Zhiguo Li, Therese Hennig, Carlos De Castro, Jadee Neff, Mitchell E. Horwitz, Thomas W. Leblanc, et al. “Morphologic Leukemia-Free State in Acute Myeloid Leukemia Is Sufficient for Successful Allogeneic Hematopoietic Stem Cell Transplant.” In Blood, 136:24–25. American Society of Hematology, 2020. https://doi.org/10.1182/blood-2020-133901.

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Amonoo, Hermioni L., Areej El-Jawahri, Thomas W. LeBlanc, Alison R. Kavanaugh, Jason A. Webb, Lara Traeger, Annemarie D. Jagielo, et al. “Post-Traumatic Stress Disorder (PTSD) Symptoms in Patients with Acute Myeloid Leukemia (AML).” In Blood, 136:44–45. American Society of Hematology, 2020. https://doi.org/10.1182/blood-2020-133857.

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Tabah, Ashley, Russell L. Knoth, David Huggar, Ronda Copher, Zhun Cao, Craig Lipkin, and Thomas W. Leblanc. “Annual Healthcare Resource Utilization and Costs in US Patients Diagnosed with Relapsed Acute Myeloid Leukemia.” In Blood, 136:13–14. American Society of Hematology, 2020. https://doi.org/10.1182/blood-2020-136762.

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El-Jawahri, Areej, Thomas W. Leblanc, Alison R. Kavanaugh, Jason A. Webb, Vicki Jackson, Toby Campbell, Nina R. O’Connor, et al. “Multi-Site Randomized Trial of Integrated Palliative and Oncology Care for Patients with Acute Myeloid Leukemia (AML).” In Blood, 136:26–27. American Society of Hematology, 2020. https://doi.org/10.1182/blood-2020-138883.

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Ryan, Kellie, Hannah Le, Svea K. Wahlstrom, Kathleen Beusterien, Oliver Will, Martine C. Maculaitis, and Thomas W. Leblanc. “How Do Progression-Free Survival and Toxicity Risks Influence Oncologist and Patient Preferences for Novel Agents in Chronic Lymphocytic Leukemia?” In Blood, 136:52–53. American Society of Hematology, 2020. https://doi.org/10.1182/blood-2020-138952.

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Vaughn, Dagny M., P Connor Johnson, Annemarie D. Jagielo, Matthew J. Reynolds, Alison R. Kavanaugh, Jason A. Webb, Amir T. Fathi, et al. “Factors Associated with High Healthcare Utilization at the End-of-Life (EOL) for Patients with Acute Myeloid Leukemia.” In Blood, 136:24–25. American Society of Hematology, 2020. https://doi.org/10.1182/blood-2020-139777.

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Sandhu, Sahil, Zoe King, Michelle Wong, Sean Bissell, Jessica Sperling, Megan Gray, William Ratliff, Kris Herring, and Thomas W. LeBlanc. “Implementation of Electronic Patient-Reported Outcomes in Routine Cancer Care at an Academic Center: Identifying Opportunities and Challenges.” Jco Oncol Pract 16, no. 11 (November 2020): e1255–63. https://doi.org/10.1200/OP.20.00357.

PMID
32926662
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Resick, Judith M., Caroline Sefcik, Robert M. Arnold, Thomas W. LeBlanc, Marie Bakitas, Margaret Quinn Rosenzweig, Thomas J. Smith, et al. “Primary Palliative Care for Patients with Advanced Hematologic Malignancies: A Pilot Trial of the SHARE Intervention.” J Palliat Med, October 19, 2020. https://doi.org/10.1089/jpm.2020.0407.

PMID
33074775
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