Thomas William LeBlanc, MD

Associate Professor of Medicine
Associate Professor in Population Health Sciences
Member of the Duke Cancer Institute
Campus mail 2424 Erwin Road, Suite 602, Durham, NC 27705
Phone (919) 668-2115
Email address

I am a medical oncologist, palliative care physician, and patient experience researcher.  My clinical practice focuses on the care of patients with hematologic malignancies, with a particular emphasis on myeloid conditions and acute leukemias including acute myeloid leukemia (AML), acute lymphocytic leukemia (ALL), myelodysplastic syndromes (MDS), and myeloproliferative neoplasms (MPNs / MPDs, CML).  

As founding Director of the Duke Cancer Patient Experience Research Program (CPEP), my research investigates common issues faced by people with cancer, including issues of symptom burden, quality of life, psychological distress, prognostic understanding, and treatment decision-making. This work aims to improve patients' experiences living with serious illnesses like blood cancers, including the integration of specialist palliative care services to provide an extra layer of support along with their comprehensive cancer care. More broadly, our team in CPEP conducts various studies of patient experience and outcomes issues in oncology, including retrospective chart review studies, comparative effectiveness work, prospective observational studies and registries, and qualitative research, along with efforts to facilitate the integration of patient-generated health data (PGHD) into routine cancer care processes, such as with electronic patient-reported outcome measures (ePROs) and other mobile health interventions (mHealth). 

This work has led to recognition as an "Inspirational Leader under 40" by the American Academy of Hospice and Palliative Medicine (AAHPM), "Fellow" status from the Academy in 2016, the 2018 international "Clinical Impact Award" from the European Association for Palliative Care, and the AAHPM "Early Career Investigator" award in 2020. I served as 2017-18 Chair of the ASCO Ethics Committee, and currently Chair the Scientific Review Committee of the NIH/NINR-funded Palliative Care Research Cooperative Group (PCRC; I have served on various national guideline panels for AML and for palliative/supportive care issues in oncology, and was inducted as a Fellow of the American Society of Clinical Oncology (FASCO) in 2021. To date I have published over 150 Medline-indexed articles, and several chapters in prominent textbooks of oncology and palliative medicine.

Education and Training

  • Fellow, Medical Oncology, Duke University School of Medicine, 2012 - 2013
  • Fellowship, Hospice And Palliative Medicine, Duke University School of Medicine, 2011 - 2012
  • Chief Medical Resident, Duke University School of Medicine, 2010 - 2011
  • Resident, Duke University School of Medicine, 2007 - 2009
  • Intern, Duke University School of Medicine, 2006 - 2007
  • M.D., Duke University, 2006


LeBlanc, Matthew Roger, Sheryl Zimmerman, Mariam Kayle, Thomas William LeBlanc, Kathryn Elizabeth Hudson, and Sophia Kustas Smith. “Fatigue trajectories in long-term non-Hodgkin lymphoma survivors.” In Journal of Clinical Oncology, Vol. 38, 2020.


LeBlanc, Thomas William, Roland B. Walter, Loriana Hernandez, Lucy Morgan, Timothy Bell, Charlotte Panter, Francois Peloquin, et al. “A fork in the road: A mixed methods study exploring why older adults with acute myeloid leukemia choose different treatment paths.” In Journal of Clinical Oncology, Vol. 38, 2020.


Pelcovits, Ari, Dominic Decker, Dana Guyer, Thomas William LeBlanc, Adam J. Olszewski, and Pamela Egan. “Impact of palliative care on end-of-life outcomes in hematologic malignancies.” In Journal of Clinical Oncology, Vol. 38, 2020.


Salinger, Maggie R., Nathan A. Boucher, Thomas W. LeBlanc, Kevin C. Oeffinger, Kathryn Pollak, Jesse D. Troy, and Arif H. Kamal. “Why palliative care is the answer to the serious illness question in payment reform.” Am J Manag Care 26, no. 4 Spec No. (April 2020): SP127–28.

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El-Jawahri, Areej, Ashley M. Nelson, Tamryn F. Gray, Stephanie J. Lee, and Thomas W. LeBlanc. “Palliative and End-of-Life Care for Patients With Hematologic Malignancies.” J Clin Oncol 38, no. 9 (March 20, 2020): 944–53.

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Loh, Kah Poh, Huiwen Xu, Anthony Back, Paul R. Duberstein, Supriya Gupta Mohile, Ronald Epstein, Colin McHugh, et al. “Patient-hematologist discordance in perceived chance of cure in hematologic malignancies: A multicenter study.” Cancer 126, no. 6 (March 15, 2020): 1306–14.

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Robles, Joanna M., Jesse D. Troy, Kristin M. Schroeder, Paul L. Martin, and Thomas W. LeBlanc. “The Effect of Limited-English Proficiency on Hematopoietic Stem Cell Transplantation Outcomes: A Retrospective Cohort Study of Hispanic Pediatric Transplant Patients at a Single Institution.” In Biology of Blood and Marrow Transplantation, 26:S195–96. ELSEVIER SCIENCE INC, 2020.


Schwartzberg, Lee, Kathryn J. Ruddy, Rudolph M. Navari, Thomas W. LeBlanc, Rebecca Clark-Snow, Rita Wickham, Gary Binder, et al. “Abstract P5-14-07: Avoidable acute care involving chemotherapy-induced nausea and vomiting (CINV) among patients with breast cancer receiving anthracycline + cyclophosphamide (AC) with NEPA prophylaxis relative to other antiemetics: An external control arm analysis.” In Poster Session Abstracts. American Association for Cancer Research, 2020.

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Wilson, Jennifer G., Diana P. English, Clark G. Owyang, Erica A. Chimelski, Corita R. Grudzen, Hong-Nei Wong, Rebecca A. Aslakson, and Rebecca A. AAHPM Research Committee Writing Group. “End-of-Life Care, Palliative Care Consultation, and Palliative Care Referral in the Emergency Department: A Systematic Review.” J Pain Symptom Manage 59, no. 2 (February 2020): 372-383.e1.

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