Thomas William LeBlanc, MD

Associate Professor of Medicine
Associate Professor in Population Health Sciences
Member of the Duke Cancer Institute
Campus mail 2424 Erwin Road, Suite 602, Durham, NC 27705
Phone (919) 668-2115
Email address

I am a medical oncologist, palliative care physician, and patient experience researcher.  My clinical practice focuses on the care of patients with hematologic malignancies, with a particular emphasis on myeloid conditions and acute leukemias including acute myeloid leukemia (AML), acute lymphocytic leukemia (ALL), myelodysplastic syndromes (MDS), and myeloproliferative neoplasms (MPNs / MPDs, CML).  

As founding Director of the Duke Cancer Patient Experience Research Program (CPEP), my research investigates common issues faced by people with cancer, including issues of symptom burden, quality of life, psychological distress, prognostic understanding, and treatment decision-making. This work aims to improve patients' experiences living with serious illnesses like blood cancers, including the integration of specialist palliative care services to provide an extra layer of support along with their comprehensive cancer care. More broadly, our team in CPEP conducts various studies of patient experience and outcomes issues in oncology, including retrospective chart review studies, comparative effectiveness work, prospective observational studies and registries, and qualitative research, along with efforts to facilitate the integration of patient-generated health data (PGHD) into routine cancer care processes, such as with electronic patient-reported outcome measures (ePROs) and other mobile health interventions (mHealth). 

This work has led to recognition as an "Inspirational Leader under 40" by the American Academy of Hospice and Palliative Medicine (AAHPM), "Fellow" status from the Academy in 2016, the 2018 international "Clinical Impact Award" from the European Association for Palliative Care, and the AAHPM "Early Career Investigator" award in 2020. I served as 2017-18 Chair of the ASCO Ethics Committee, and currently Chair the Scientific Review Committee of the NIH/NINR-funded Palliative Care Research Cooperative Group (PCRC; I have served on various national guideline panels for AML and for palliative/supportive care issues in oncology, and was inducted as a Fellow of the American Society of Clinical Oncology (FASCO) in 2021. To date I have published over 150 Medline-indexed articles, and several chapters in prominent textbooks of oncology and palliative medicine.

Education and Training

  • Fellow, Medical Oncology, Duke University School of Medicine, 2012 - 2013
  • Fellowship, Hospice And Palliative Medicine, Duke University School of Medicine, 2011 - 2012
  • Chief Medical Resident, Duke University School of Medicine, 2010 - 2011
  • Resident, Duke University School of Medicine, 2007 - 2009
  • Intern, Duke University School of Medicine, 2006 - 2007
  • M.D., Duke University, 2006


Navari, Rudolph M., Kathryn J. Ruddy, Thomas W. LeBlanc, Rebecca Clark-Snow, Rita J. Wickham, Gary Binder, Tammy Coberly, Ravi Potluri, Luke M. Schmerold, and Eric J. Roeland. “Impact of Addition of Carboplatin AUC ≥ 4 to Antiemetic Guidelines for Triple Antiemetic Prophylaxis: A Gap in Quality of Care, Guideline Adoption, and Avoiding Acute Care.” Jco Oncol Pract 16, no. 2 (February 2020): e132–38.

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Yuen, Eva Y. N., Alexandra K. Zaleta, Shauna McManus, Joanne S. Buzaglo, Thomas W. LeBlanc, Kathryn Hamilton, and Kevin Stein. “Unintentional weight loss, its associated burden, and perceived weight status in people with cancer.” Support Care Cancer 28, no. 1 (January 2020): 329–39.

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Marmor, Meghan, Andrea Jonas, Alicia Mirza, Elika Rad, Hongnei Wong, Rebecca A. Aslakson, and Rebecca A. AAHPM Research Committee Writing Group. “Opportunities to Improve Utilization of Palliative Care Among Adults With Cystic Fibrosis: A Systematic Review.” J Pain Symptom Manage 58, no. 6 (December 2019): 1100-1112.e1.

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Morris, Heather, Meredith T. Moorman, Melissa C. Mackey, Harry P. Erba, Thomas W. LeBlanc, David A. Rizzieri, Ian Barak, Zhiguo Li, and Tanya Zapolskaya. “Incidence of Invasive Fungal Infections in Acute Leukemia Patients Utilizing Micafungin Prophylaxis Compared to Second-Generation Azole Prophylaxis.” In Blood, 134:5105–5105. American Society of Hematology, 2019.

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LeBlanc, Thomas W., Roland B. Walter, Loriana Hernandez-Aldama, Kate Sully, Timothy J. Bell, Chloe Johnson, Francois Peloquin, et al. “Treatment Decision Making in AML: Factors of Importance to Clinicians, AML Patients and Their Family.” In Blood, 134:3498–3498. American Society of Hematology, 2019.

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Zaleta, Alexandra K., Pierre Gardan, Shauna McManus, Melissa F. Miller, Kelly Clark, Nicole E. Nicksic, Hildy Dillon, et al. “Cancer-Related Distress and Unmet Needs Among Acute Myeloid Leukemia Survivors.” In Blood, 134:4787–4787. American Society of Hematology, 2019.

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