Tomokazu Souma, MD, PhD

Medical Instructor in the Department of Medicine
Affiliate of the Regeneration Next Initiative
Email address tomokazu.souma@duke.edu

Education and Training

  • Post-doctoral Fellowship, Feinberg Cardiovascular Research Institute, Northwestern University, 2013 - 2014
  • Post-doctoral Fellowship, Department Of Medical Biochemistry, Tohoku University (Japan), 2012 - 2013
  • Ph.D., Tohoku University (Japan), 2012
  • M.D., Shimane University, 2004

Publications

Souma, Tomokazu, Michiaki Abe, Takashi Moriguchi, Jun Takai, Noriko Yanagisawa-Miyazawa, Eisuke Shibata, Yasutoshi Akiyama, et al. “Luminal alkalinization attenuates proteinuria-induced oxidative damage in proximal tubular cells..” J Am Soc Nephrol 22, no. 4 (April 2011): 635–48. https://doi.org/10.1681/ASN.2009111130.

PMID
21372211
Full Text

Abe, Michiaki, Tomokazu Souma, Yanagisawa-Miyazawa Noriko, Yasutoshi Akiyama, Takafumi Toyohara, Masayuki Tanemoto, Takaaki Abe, Hiroshi Sato, Masaaki Nakayama, and Sadayoshi Ito. “High glucose augments susceptibility of AT1R-induced NAD(P)H oxidase activation in mesangial cell.” In Endocrine Journal, 57:S400–S400. JAPAN ENDOCRINE SOC, 2010.

Scholars@Duke

Miyazawa, Noriko, Michiaki Abe, Tomokazu Souma, Masayuki Tanemoto, Takaaki Abe, Masaaki Nakayama, and Sadayoshi Ito. “Methylglyoxal augments intracellular oxidative stress in human aortic endothelial cells..” Free Radic Res 44, no. 1 (January 2010): 101–7. https://doi.org/10.3109/10715760903321788.

PMID
19886746
Full Text

Abe, Michiaki, Takafumi Toyohara, Akiko Ishii, Takehiro Suzuki, Naoya Noguchi, Yasutoshi Akiyama, Hiromi O. Shiwaku, et al. “The HMG-CoA reductase inhibitor pravastatin stimulates insulin secretion through organic anion transporter polypeptides..” Drug Metab Pharmacokinet 25, no. 3 (2010): 274–82.

PMID
20610886
Scholars@Duke

Toyohara, Takafumi, Takehiro Suzuki, Ryo Morimoto, Yasutoshi Akiyama, Tomokazu Souma, Hiromi O. Shiwaku, Yoichi Takeuchi, et al. “SLCO4C1 transporter eliminates uremic toxins and attenuates hypertension and renal inflammation..” J Am Soc Nephrol 20, no. 12 (December 2009): 2546–55. https://doi.org/10.1681/ASN.2009070696.

PMID
19875811
Full Text

Souma, Tomokazu, Michiaki Abe, Yasutoshi Akiyama, Takafumi Toyohara, Shiwaku O. Hiromi, Takehiro Suzuki, Masayuki Tanemoto, Takaaki Abe, and Sadayoshi Ito. “Acidification Aggravates Fatty Acid-Bound Albumin-Induced Superoxide Production in Renal Proximal Tubular Cells Through Activation of Pyk2 Pathways.” In Hypertension, 54:E84–E84. LIPPINCOTT WILLIAMS & WILKINS, 2009.

Scholars@Duke

Souma, Tomokazu, Michiaki Abe, Yasutoshi Akiyama, Takafumi Toyohara, Takehiro Suzuki, Hiromi O. Shiwaku, Masayuki Tanemoto, Takaaki Abe, and Sadayoshi Ito. “Low luminal pH aggravates fatty acid bound albumin induced O-2(.-) production in renal proximal tubular cell.” In Faseb Journal, Vol. 23. FEDERATION AMER SOC EXP BIOL, 2009.

Scholars@Duke

Souma, Tomokazu, Michiaki Abe, Yasutoshi Akiyama, Takafumi Toyohara, Hiromi O. Shiwaku, Takehiro Suzuki, Masayuki Tanemoto, Takaaki Abe, and Sadayoshi Ito. “LOW LUMINAL PH AGGRAVATES FATTY ACID BOUND ALBUMIN INDUCED O2 center dot- PRODUCTION IN RENAL PROXIMAL TUBULAR CELL.” In Journal of Vascular Research, 46:99–99. KARGER, 2009.

Scholars@Duke

Souma, Tomokazu, Michiaki Abe, Yasutoshi Akiyama, Takafumi Toyohara, Hiromi O. Shiwaku, Takehiro Suzuki, Masayuki Tanemoto, Takaaki Abe, and Sadayoshi Ito. “LOW LUMINAL pH AGGRAVATES FATTY ACID BOUD ALBUMIN INDUCED O-2(center dot-) PRODUCTION IN RENAL PROXIMAL TUBULAR CELL.” In Journal of Physiological Sciences, 59:485–485, 2009.

Scholars@Duke

Bockenhauer, D., M. Cruwys, R. Kleta, L. F. Halperin, P. Wildgoose, T. Souma, N. Nukiwa, et al. “Antenatal Bartter's syndrome: why is this not a lethal condition?.” Qjm 101, no. 12 (December 2008): 927–42. https://doi.org/10.1093/qjmed/hcn119.

PMID
18829713
Full Text

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